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People in the early stages of CKD usually do not feel sick at all. People whose kidney disease has gotten worse may:

  • need to urinate more often or less often
  • feel tired
  • lose their appetite or experience nausea and vomiting
  • have swelling in their hands or feet
  • feel itchy or numb
  • get drowsy or have trouble concentrating
  • have darkened skin
  • have muscle cramps
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