• Co-investigator for a randomised, un-blinded controlled trial on intravenous levetiracetam versus phenytoin in acute convulsive status epilepticus in the emergency department (EcLIPSE trial).
• Principal Investigator previously at Alder Hey Children’s Hospital for the Fenfluramine in Dravet syndrome study by Zogenix pharmaceuticals.
• Principal Investigator previously at Alder Hey Children’s Hospital for the study ‘Epileptic encephalopathy Longitudinal Omics Study’ – led by Professor Pal, Kings College, London.
• Principal Investigator previously at Alder Hey Children’s Hospital for the study ‘Reading difficulties in children with benign rolandic epilepsy’ – initiated by Lancaster University.
• I have participated in and have recruited a number of patients into several research studies (ICISS, SANAD2, VIPS, PUDDLS, Drooling reduction study, Enceph-UK and CHiMES).

Publications

• Congenital trigeminal anaesthesia: a rare preventable cause of visual loss in children. Iyer A, et al. BMJ Case Report. 3 July 2012.
• VGKC-complex antibody mediated encephalitis presenting with psychiatric features and neuroleptic malignant syndrome - further expanding the phenotype. Iyer A, et al. Dev Med Child Neurol. 2012; 54: 575-6.
• Late-onset sensorineural hearing loss due to congenital cytomegalovirus infection: could head injury be a trigger? Iyer A, et al. Acta Paediatr. 2013; 102: e2-3.
• Transitional services for adolescents with epilepsy in the UK: A survey. Iyer A, Appleton R. Seizure 2013; 22:433-7.
• Management of reflex anoxic seizures in children. Iyer A, Appleton R. Arch Dis Child. 2013; 98: 714-7.
• Spontaneous spinal epidural haematoma mimicking meningitis in a 2-year-old child--a case report and literature review. Jumani DB, Littlewood R, Iyer A, et al. Child’s Nerv Syst. 2013; 29:1795-8.
• A review of the current literature and a guide to the early diagnosis of autoimmune disorders associated with neuromyelitis optica. Iyer A, et al. Autoimmunity 2014; 47(3):154-161.
• Transverse myelitis associated with an itchy rash and hyperCKemia – Neuromyelitis Optica associated with Dermatitis Herpetiformis. Iyer A et al. JAMA Neurology 2014;71(5):630-633.
• Doing challenging research studies in a patient-centred way: a qualitative study to inform a randomised controlled trial in the paediatric emergency care setting.Woolfall K, Young B, Frith L, Appleton R, Iyer A, Messahel S, Hickey H, Gamble C. BMJ Open. 2014 May 15;4(5).
• Pharmacotherapy of focal epilepsy. Iyer A, Marson A. Expert Opin Pharmacother. 2014 Aug;15(11):1543-51.
• Sampling the upper respiratory tract for enteroviral infection is important in the investigation of an acute neurological illness in children. Varghese R, Iyer A, Hunter K, Cargill JS, Cooke RP. Eur J Paediatr Neurol. 2015 Jul;19(4):494-5. PMID: 25868937.
• Anti-N-Methyl-D-Aspartate Receptor Encephalitis In A Young Child With Histological Evidence On Brain Biopsy Of Coexistent Herpes Simplex Virus Type 1 Infection. Ellul MA, Griffiths MJ, Iyer A, Avula S, Defres S, Baborie A, Vincent A, Martin NG, Sadarangani M, Pollard AJ, Solomon T, Kneen R. Pediatr Infect Dis J. 2016 Mar;35(3):347-9.
• Epilepsy: addressing the transition from pediatric to adult care. Rajendran S, Iyer A. Adolesc Health Med Ther.2016 Jun 27;7:77-87.
• Improving outcomes in infantile spasms: role of pharmacotherapy. Iyer A, Appleton R, Paediatrics Drugs. 2016 Oct; 18(5):357-66.
• Consensus-based guidelines for Video EEG monitoring in the pre-surgical evaluation of children with epilepsy in the UK. Pressler RM, Seri S, Kane N, Marland T, Goyal S, Iyer A, Warren E, Notghi L, Bill P, Thornton R, Appleton R, Doyle S, Ruston S, Worley A, Boyd SG; CESS Clinical Neurophysiology working group. Seizure.2017 Aug;50:6-11.
• Emergency treatment with levetiracetam or phenytoin in status epilepticus in children-the EcLiPSE study: study protocol for a randomised controlled trial. Lyttle MD, Gamble C, Messahel S, Hickey H, Iyer A, Woolfall K, Humphreys A, Bacon NEA, Roper L, Babl FE, Dalziel SR, Ryan M, Appleton RE; supported by Paediatric Emergency Research in the United Kingdon and Ireland (PERUKI) Trials. 2017 Jun 19;18(1):283.
• Reading comprehension difficulties in children with rolandic epilepsy. Currie NK, Lew AR, Palmer TM, Basu H, De Goede C, Iyer A, Cain K. Dev Med Child Neurol. 2017 Dec 14.