Kev Ntsuas SGPT (ALT): Nws Ntsuas Dab Tsi, Nws Qhia Tsis Tau Koj Dab Tsi, thiab Yuav Nyeem Koj Daim Ntawv Qhia Li Cas

Tus yuam sij takeaways

• SGPT thiab ALT yog tib qho kev kuajSGPT yog lub npe hauv chav kuaj Indian qub rau alanine aminotransferase.
• SGPT qhia txog kev raug mob ntawm cov hlwb siab, tsis yog nws qhov ua rau: rog siab, kab mob siab viral, cawv, tshuaj thiab tshuaj ntxiv tuaj yeem ua rau nws nce siab.
• Ib qho SGPT ib txwm ua rau peb ntseeg siab tab sis tsis yog qhov xaus lus.: mob fibrosis thiab cirrhosis feem ntau khiav nrog cov enzymes ib txwm lossis ze li qub.
• Tus lej nkaus xwb txhais tau tias me me: SGPT raug txhais ua ke nrog SGOT (AST), ALP, GGT, bilirubin, albumin, suav cov platelet thiab kev thaij duab.
• Cov qib siv sib txawv ntawm cov chaw kuaj mob: ib txwm nyeem koj tus nqi tawm tsam qhov ntau ntawm koj daim ntawv qhia.

Ib nrais muag

Kuj hu ua

• Kev kuaj ALT, alanine aminotransferase
• Kev kuaj ntshav SGPT, cov qib SGPT
• Ib feem ntawm "LFT", "kev kuaj siab", "qhia txog daim siab"
• Feem ntau hais hauv Is Nrias teb tias yog "kev kuaj mob siab enzyme" lossis "kev kuaj mob jaundice", SGPT yog ib feem ntawm cov vaj huam sib luag no, tsis yog tag nrho cov vaj huam sib luag.

Kev xeem SGPT yog dab tsi

Alanine aminotransferase yog ib qho enzyme uas nyob hauv cov hlwb siab, nrog rau cov me me hauv lub raum, lub plawv thiab cov leeg nqaij pob txha. Cov enzyme no pab hloov cov pawg amino thaum lub sijhawm ua cov amino acid metabolism. Thaum cov hlwb siab o, ntxhov siab lossis tuag, alanine aminotransferase tawm thiab cov ntshav nce siab.

Vim tias cov enzyme no yog ib qho tshwj xeeb rau daim siab, SGPT yog ib qho cim qhia txog kev raug mob ntawm daim siab. Txawm li cas los xij, SGPT ntsuas kev raug mob , tsis yog kev ua haujlwm . Kev ua haujlwm ntawm daim siab pom tau zoo dua los ntawm albumin, prothrombin time/INR thiab bilirubin.

Leej twg yuav tsum tau txais qhov kev xeem no

• Cov neeg uas muaj cov tsos mob qhia tias muaj kab mob siabmob daj ntseg, zis dub, quav dawb paug, xeev siab tas li, mob plab sab xis sab saud, qaug zog lossis khaus uas tsis paub meej.
• Cov neeg noj tshuaj uas paub tias cuam tshuam rau lub siabtshuaj kho mob ntsws, tshuaj methotrexate, qee yam tshuaj tiv thaiv qaug dab peg, tshuaj tiv thaiv kab mob kis, qee yam tshuaj tua kab mob fungal thiab tshuaj tua kab mob. Tus kws sau ntawv yuav teem sijhawm saib xyuas.
• Cov neeg noj cov tshuaj AYUSH, cov tshuaj ntsuab lossis cov tshuaj pab kom lub cev muaj zog/ua kom lub cev muaj zogcov no yog ib qho ua rau muaj kev puas tsuaj rau daim siab los ntawm tshuaj hauv Is Nrias teb.
• Cov neeg uas muaj cov yam ntxwv ntawm kev pheej hmoo ntawm kev hloov pauv hauv lub cevmob ntshav qab zib hom 2, ntshav siab, roj hauv lub cev ntau dhau, rog hauv nruab nrab. Cov neeg Esxias Qab Teb muaj kab mob siab metabolic thaum lawv lub cev hnyav qis dua lwm cov pej xeem.
• Cov neeg uas paub lossis xav tias muaj kab mob siab B lossis C, ua ib feem ntawm kev saib xyuas uas tus kws kho mob siab lossis kws kho mob txiav txim siab.
• Cov neeg uas haus dej cawv tsis tu ncua lossis haus cawv ntau dhau.
• Cov neeg uas muaj rog rog tsis tau pom ntawm ultrasound.

Kev kuaj mob SGPT tsis tu ncua rau ib tus neeg uas muaj mob zoo thiab tsis muaj yam ua rau muaj kev pheej hmoo tsis yog ib qho kev pom zoo thoob ntiaj teb; feem ntau nws suav nrog cov pob khoom kuaj mob Is Nrias teb, thiab qhov txawv txav me me hauv qhov chaw ntawd xav tau kev txhais lus zoo dua li kev ceeb toom.

Vim li cas thiaj ua qhov kev xeem SGPT

• Txhawm rau nrhiav kev raug mob ntawm cov hlwb siab thaum muaj cov tsos mob lossis cov yam ua rau muaj kev pheej hmoo.
• Yuav pab piav qhia txog teeb meem ntawm daim siabTus qauv ntawm SGPT piv rau ALP thiab GGT pab cais kev raug mob ntawm daim siab los ntawm cov teeb meem cholestatic (cov kua tsib ntws).
• Yuav tsum tau saib xyuas lub sijhawm: cov qauv ntawm kev rov ua dua cov kev xeem muaj txiaj ntsig ntau dua li kev nyeem ib zaug xwb.
• Txhawm rau saib xyuas kev nyab xeeb ntawm cov tshuaj thaum lub sijhawm kho mob uas tuaj yeem cuam tshuam rau lub siab.
• Yuav taug qab cov lus teb nyob rau hauv cov mob xws li mob siab ntev lossis mob siab autoimmune, nrog rau lwm yam kev kuaj mob.

Tej yam uas qhov kev xeem SGPT tsis tuaj yeem ntes tau lossis tsis suav nrog

Qhov no yog qhov feem ntau cov ntawv ceeb toom tsis hais tawm, thiab nws tseem ceeb dua li tus lej nws tus kheej.

• SGPT tsis tuaj yeem qhia koj qhov ua rau. Kab mob siab los ntawm cov kab mob sib kis, kab mob siab metabolic, cawv, tshuaj, tshuaj noj ntxiv, kab mob siab autoimmune, kab mob celiac, kab mob thyroid thiab kev raug mob ntawm cov leeg nqaij tuaj yeem ua rau SGPT nce siab.
• SGPT tsis tuaj yeem zam tau qhov mob cirrhosis lossis mob fibrosis uas mob heev lawm. Cov enzyme feem ntau poob qis mus rau qhov qub thaum cov qhov txhab loj zuj zus thiab cov hlwb ua haujlwm ploj mus. SGPT ib txwm tsis yog pov thawj ntawm lub siab noj qab haus huv.
• SGPT tsis tuaj yeem ntsuas qib rog lossis fibrosis. Nws tsis hais dab tsi txog qhov muaj steatosis, o, lossis caws pliav ntau npaum li cas. Qhov ntawd yuav tsum tau siv duab thaij, elastography, cov qhab nia tsis phais, lossis qee zaum biopsy.
• SGPT tsis tuaj yeem kuaj pom mob qog noj ntshav hauv siab lossis cov qog nqaij hlav hauv siab. Mob qog nqaij hlav hauv siab tuaj yeem tshwm sim nrog cov enzymes ib txwm muaj. Yuav tsum tau thaij duab.
• SGPT tsis tuaj yeem ntsuas kev ua haujlwm ntawm lub siab. Lub siab uas tsis ua haujlwm tsim cov protein lossis cov bilirubin ntshiab tseem yuav qhia tau tias muaj cov enzyme nce me ntsis.
• SGPT tsis tuaj yeem tshem tawm qhov kev thaiv ntawm cov kua tsib lossis kab mob gallstone. ALP, GGT, bilirubin thiab ultrasound teb cov lus nug ntawd.
• SGPT tsis yog tsuas yog rau lub siab xwb. Kev raug mob ntawm cov leeg pob txha, kev tawm dag zog hnyav, thiab qee yam mob ntawm cov leeg nqaij tuaj yeem ua rau nws loj hlob yam tsis muaj kab mob siab.

Yog tias qhov tshwm sim zoo li qub txhais tau tias cov enzyme tsis tau nce siab hauv cov qauv ntawd thaum lub sijhawm ntawd. Qhov no tsis tau txhais hais tias kab mob siab tau raug tshem tawm. Yog tias koj cov tsos mob tseem muaj txawm tias SGPT zoo li qub, rov qab mus ntsib koj tus kws kho mob dua li xav tias lub siab tau raug tshem tawm lawm.

Kev ntsuam xyuas sib txuas tab sis sib txawv

Tsis muaj ib qho kev kuaj twg uas yog "thawj zaug" thoob plaws ntiaj teb. Yog tias qhov teeb meem uas tshwm sim yog mob daj ntseg, bilirubin thiab kev kuaj ultrasound ntawm cov biliary feem ntau ua rau. Yog tias qhov teeb meem yog daim siab rog uas muaj feem yuav muaj teeb meem metabolic, cov enzymes ntxiv rau kev ntsuam xyuas kev pheej hmoo ntawm fibrosis ua rau. Yog tias qhov teeb meem yog mob sab xis sab saud uas qhia txog pob zeb hauv lub zais zis, kev kuaj ultrasound ua rau.

Yuav npaj li cas

Cov lus qhia npaj ua haujlwm tau thiab txawv ntawm cov chaw kuaj mob thiab cov tsev kho mob. Cov lus qhia sau ntawm koj lub chaw kuaj mob muaj qhov tseem ceeb dua txhua yam ntawm nplooj ntawv no.

• Kev yoo mov: Feem ntau SGPT tsis tas yuav tsum yoo mov. Tej zaum yuav tsum yoo mov yog tias kuaj cov roj lipid lossis cov piam thaj hauv kev yoo mov tib lub sijhawm.
• Tshuaj thiab tshuaj ntxiv: nqa ib daim ntawv teev tag nrho, suav nrog kev siv paracetamol, kev kho mob ntsws, statins, tshuaj tua kab mob, tshuaj tua kab mob, AYUSH thiab cov tshuaj ntsuab, hmoov protein thiab cov tshuaj ntxiv rau hauv gym. Tsis txhob tsum cov tshuaj uas tau muab rau koj kom "txhim kho" qhov tshwm sim, nrog tus kws kho mob tham ua ntej.
• Dej Cawv: Qhia rau koj tus kws kho mob txog kev haus dej cawv tsis ntev los no es tsis txhob zais nws; kev haus dej cawv tsis ntev los no cuam tshuam rau kev txhais lus.
• Strenuous exercise: Kev tawm dag zog hnyav lossis kev khiav ntev ua ntej hnub lossis ob hnub ua ntej tuaj yeem ua rau SGPT thiab SGOT nce siab. Hais txog qhov no, thiab xav txog kev tsis txhob tawm dag zog hnyav dhau ua ntej.

Yog koj muaj mob ntshav qab zib uas tab tom kho mob kom txo cov piam thaj (glycolysis)

Yog tias tau thov kom yoo mov rau lwm yam kev kuaj mob hauv tib qho kev kuaj mob, nug tus kws kho mob seb yuav siv sijhawm insulin lossis sulfonylurea li cas, thiab nqa cov khoom noj uas muaj qabzib. Kev yoo mov ntev ntev tsis muaj kev saib xyuas ntawm cov tshuaj no yuav ua rau muaj kev pheej hmoo ntawm hypoglycemia.

Yog koj xeeb tub

Tsis tas yuav yoo mov rau SGPT. Qhia rau lub chaw kuaj mob tias koj cev xeeb tub, vim tias muaj ntau qhov txiaj ntsig hauv pawg neeg no txhais tau txawv thaum cev xeeb tub.

Yog tias koj muaj CKD, lub plawv tsis ua haujlwm lossis kev txwv cov kua dej

Tsis txhob haus dej ntau dhau qhov koj tau teev tseg raws li cov lus qhia dav dav txog "hydration". Ua raws li qhov koj pab neeg kho mob tau teev tseg.

Cov me nyuam

Kev ntsuas ntshav rau menyuam yaus siv cov ntim me me thiab cov qib ntsuas raws li menyuam yaus xav tau. Kev yoo mov ntev tsis haum rau cov menyuam yaus tshwj tsis yog tus kws kho mob menyuam yaus qhia tshwj xeeb.

Muaj dab tsi tshwm sim thaum lub sijhawm xeem thiab nws siv sijhawm ntev npaum li cas

Tus kws kho mob ntshav yuav ntxuav daim tawv nqaij, muab ib txoj hlab ntshav (tourniquet) thiab rho ib qho ntshav me me los ntawm cov hlab ntsha hauv caj npab. Kev rho ntshav nws tus kheej siv sijhawm tsawg dua ib feeb. Yog tias suav nrog kev sau npe, kev mus ntsib kws kho mob feem ntau siv sijhawm li 5 txog 15 feeb. Yuav nias rau ntawm qhov chaw ntawd thiab muab ib daim ntaub qhwv me me rau.

Feem ntau cov chaw kuaj mob yuav muab cov txiaj ntsig SGPT rau tib hnub ua haujlwm lossis hnub ua haujlwm tom ntej, vim tias kev ntsuas yog ib qho kev ntsuas tsis siv neeg. Kev ua tiav raws sijhawm nyob ntawm chav tsev, lub sijhawm kawg ntawm kev sau thiab seb cov qauv puas tau coj mus rau qhov chaw sau lossis chaw kuaj mob loj.

Nkag siab txog koj daim ntawv qhia SGPT

SGPT yog qhia ua units per litre (U/L) lossis international units per litre (IU/L). Cov nqi siv rau kev ntsuas sib txawv nyob ntawm txoj kev ntsuas, chav kuaj mob, poj niam txiv neej thiab hnub nyoog, thiab qee lub chav kuaj mob siv cov nqi qis dua li lwm lub. Siv cov nqi uas luam tawm rau ntawm koj daim ntawv qhia. Tsis txhob muab koj tus nqi piv rau lwm qhov nqi los ntawm lwm lub chav kuaj mob lossis lub vev xaib.

Cov ntsiab cai dav dav uas koj tus kws kho mob siv tau:

• Qhov siab me me: feem ntau yog kab mob siab rog (metabolic), cawv, tshuaj lossis tshuaj ntxiv. Feem ntau kho tau los ntawm kev txheeb xyuas qhov ua rau muaj kab mob, rov kuaj dua thiab kev ntsuam xyuas qhov muaj feem yuav mob fibrosis.
• Qhov siab cim: ua rau muaj feem yuav muaj kab mob siab kis thoob plaws (xws li kab mob siab A thiab kab mob siab E, ob qho tib si pom muaj nyob rau hauv Is Nrias teb), kev raug mob siab los ntawm tshuaj, kev raug mob ischemic lossis kab mob siab autoimmune. Cov no xav tau kev soj ntsuam sai sai.
• Tus qauv tseem ceeb dua li tus duab ib leeg: SGPT tseem ceeb qhia tias muaj kev raug mob rau daim siab; ALP thiab GGT tseem ceeb qhia tias muaj cov txheej txheem cholestatic.
• Qhov sib txawv tseem ceeb: Tus neeg mob uas muaj mob hnyav zuj zus tuaj, qhov uas SGPT poob qis tsis yog xov xwm zoo.
• Tsawg SGPT feem ntau tsis muaj teeb meem kev kho mob ntawm nws tus kheej.

Cov lej tshwj xeeb xws li 75, 90, 110 lossis 200 U/L tsis tuaj yeem suav tias yog "me me" lossis "loj heev" yog tias cais ua ib qho xwb. Tus nqi tib yam muaj lub ntsiab lus sib txawv heev rau ib tus neeg uas muaj mob kub taub hau ob hnub thiab mob daj ntseg, rau ib tus neeg uas tau txais kev kho mob tiv thaiv kab mob ntsws, thiab rau ib tus neeg uas tsis muaj tsos mob uas muaj roj ntau hauv siab thaum kuaj ultrasound. Tsuas yog tus kws kho mob uas tau thov kom kuaj, nrog koj keeb kwm, kev kuaj mob thiab lwm tus neeg hauv pawg neeg, thiaj li txhais tau nws. Cov txiaj ntsig sib txawv nyob ntawm tus neeg mob qhov xwm txheej.

Lus Cim Txog Lub Npe: yam uas yav tas los hu ua NAFLD tam sim no hu ua MASLD (metabolic dysfunction-associated steatotic liver disease), NASH tam sim no yog MASH , lub ntsiab lus yog steatotic liver disease , thiab MetALD piav qhia txog kev sib koom ua ke ntawm metabolic thiab cawv uas cuam tshuam nrog (multi-society Delphi consensus, 2023). Cov ntawv qhia qub tseem yuav siv cov lus dhau los.

Thaum cov txiaj ntsig SGPT tuaj yeem ua rau yuam kev

Cov ua rau muaj SGPT cuav lossis dag ntxias

• Kev tawm dag zog hnyav lossis kev raug mob ntawm cov leeg: cov leeg pob txha muaj alanine aminotransferase; kev cob qhia hnyav, kev poob lossis kev txhaj tshuaj intramuscular tuaj yeem tsa nws yam tsis muaj kab mob siab.
• Kev rhuav tshem cov ntshav ntawm cov qauv thaum lub sijhawm sau lossis thauj mus los tuaj yeem cuam tshuam nrog ntau cov analytes.
• Haus dej cawv tsis ntev los no los yog noj tshuaj ntxiv tshiab tej zaum yuav ua rau muaj kev nce siab ib ntus uas daws tau thaum rov kuaj dua.
• Kab mob Celiac, cov kab mob thyroid thiab cov kab mob leeg tuaj yeem ua rau muaj qhov siab me me tas li uas yuam kev rau kab mob siab thawj zaug.

Cov ua rau muaj SGPT cuav lossis qis qis

• Kev tsim cov cirrhosis: cov enzymes feem ntau rov qab zoo li qub thaum cov hepatocyte hnyav poob qis, yog li SGPT ib txwm muaj peev xwm nyob ua ke nrog cov kab mob hnyav.
• Kab mob siab B lossis C uas nyob ntev hauv theem tsis ua haujlwmcov enzymes ib txwm muaj txawm tias muaj kev kis kab mob thiab tej zaum yuav muaj fibrosis.
• Kab mob hloov pauv: cov enzymes hauv cov kab mob siab ntev thiab MASLD nce thiab nqis, yog li ib qho nqi ib txwm yuav poob rau hauv lub qhov rais ntsiag to.
• Tsis muaj vitamin B6 (pyridoxine) thiab kev ntxuav ntshav mus ntev tuaj yeem txo qis kev ua ub no uas ntsuas tau.
• Cov kev txwv siab tshaj plaws ntawm kev ntsuam xyuas sib txawv: qee lub chaw kuaj mob siv cov kev txiav tawm siab dua, yog li tus nqi cim qhia tias yog ib txwm muaj hauv ib lub chaw kuaj mob yuav raug cim siab hauv lwm qhov.

Kev Pheej Hmoo thiab Kev Nyab Xeeb

Kev kuaj ntshav ntawm cov hlab ntsha

Kev siv cov hlab ntsha venepuncture niaj hnub muaj kev pheej hmoo tsawg tab sis muaj tseeb tiag: mob ib ntus, mob ntshav liab, qaug zog lossis tsaus muag, thiab tsis tshua muaj cov ntshav me me lossis kev kis kab mob hauv zos. Cov neeg uas noj tshuaj anticoagulants lossis muaj teeb meem ntshav yuav mob ntshav ntau dua thiab yuav tsum qhia rau tus kws kho mob ntshav.

Kev kuaj ntshav capillary lossis menyuam yaus

Kev kuaj pob taws lossis ntiv tes rau cov menyuam mos thiab cov menyuam yaus me ua rau tsis xis nyob ib ntus thiab mob me ntsis; cov ntim kuaj me me, thiab qee zaum yuav tsum tau kuaj dua yog tias cov qauv tsis txaus lossis cov ntshav tsis txaus.

Tsis muaj kev siv tshuaj sib piv, tshuaj tua kab mob, lossis tshuaj loog hauv kev kuaj SGPT.

Cov xwm txheej tshwj xeeb

Cev xeeb tub

Kev hloov me me tuaj yeem tshwm sim thaum cev xeeb tub, tab sis cov transaminases uas siab dhau yuav tsum tsis txhob raug tso tseg tias yog kev hloov pauv cev xeeb tub ib txwm muaj. Intrahepatic cholestasis ntawm cev xeeb tub, pre-eclampsia nrog kev koom tes ntawm daim siab, HELLP syndrome, hyperemesis gravidarum thiab mob siab viral hepatitis (suav nrog hepatitis E, uas tuaj yeem hnyav thaum cev xeeb tub hauv Is Nrias teb) txhua yam yuav tsum tau kuaj xyuas kev yug menyuam.

Cov me nyuam

Cov menyuam yaus cov ntshav siab txawv ntawm cov neeg laus. Qhov uas ib tug menyuam yaus cov ntshav siab nce siab tas li ua rau muaj kev xav txog cov teeb meem ntawm kev zom zaub mov, kev hloov pauv caj ces, kev tiv thaiv kab mob tsis pub nws nkag mus rau hauv lub cev thiab cov leeg nqaij nrog rau kab mob siab steatotic, thiab yuav tsum tau soj ntsuam los ntawm kws kho mob menyuam yaus lossis kws kho mob plab hnyuv rau menyuam yaus.

Cov laus

Kev siv tshuaj ntau dhau ua rau muaj feem yuav raug mob siab vim yog tshuaj. Kev nce ntawm cov enzyme yuav tsis ntau txawm tias muaj mob hnyav, yog li ntawd, cov duab thiab cov cim qhia kev ua haujlwm muaj qhov hnyav ntxiv.

Cov neeg mob ntshav qab zib

Kab mob siab steatosis feem ntau tshwm sim nrog rau ntshav qab zib hom 2, thiab kev pheej hmoo ntawm fibrosis siab dua. Cov qib enzyme tsis sib raug zoo nrog fibrosis, yog li kev ntsuam xyuas fibrosis yog coj los ntawm tus kws kho mob es tsis yog los ntawm SGPT ib leeg.

Cov neeg uas muaj CKD lossis tab tom ntxuav dialysis

Cov theem transaminase feem ntau qis dua rau cov neeg uas ntxuav ntshav, yog li ntawd, SGPT "ib txwm" tsis ua rau neeg ntseeg siab dua, thiab feem ntau siv cov qauv qis dua rau kev ntsuam xyuas ntxiv.

Cov neeg uas muaj teeb meem plawv tsis ua haujlwm

Kev txhaws ntawm daim siab thiab cov zis tsawg tuaj yeem ua rau SGPT thiab SGOT nce siab yam tsis muaj kab mob siab thawj zaug. Yuav tsum xav txog qhov xwm txheej ntawm lub plawv thaum txhais lus.

Kev xeem SGPT hauv Is Nrias teb

• Terminology: Cov chaw soj nstuam hauv Is Nrias teb tau tshaj tawm dav dav SGPT thiab SGOT es tsis yog ALT thiab AST. Cov kev xeem zoo ib yam; tsuas yog lub npe sib txawv xwb. Ob qho tib si feem ntau tshwm sim rau ntawm tib daim ntawv luam tawm LFT.
• Kab mob siab A thiab kab mob siab E tseem yog cov ua rau muaj kab mob siab hepatitis mob hnyav nrog cov transaminases siab hauv Is Nrias teb, tshwj xeeb tshaj yog rau cov tub ntxhais hluas, thiab kab mob siab E muaj kev pheej hmoo ntxiv thaum cev xeeb tub.
• Kev kho mob ntsws yog ib qho ua rau mob siab vim yog tshuaj vim yog tus kab mob ntsws. Kev saib xyuas thiab kev txiav txim siab txog koob tshuaj yog nyob ntawm tus kws kho mob, tsis txhob tsum ATT ntawm koj tus kheej.
• AYUSH, tshuaj ntsuab thiab cov tshuaj ntxiv rau hauv lub gym yog ib qho ua rau lub siab raug mob uas tau lees paub thiab tsis tau tshaj tawm hauv kev xyaum Is Nrias teb. Qhia txhua yam koj noj, suav nrog cov khoom muag ua "ntuj" lossis "kev tshem tawm lub siab". Cov lus thov tias cov khoom kho lossis thim rov qab kab mob siab kuj raug ua txhaum ntawm Txoj Cai Tshuaj thiab Kev Kho Mob Khawv Koob (Kev Tshaj Tawm Tsis Zoo), 1954.
• Kab mob siab metabolic thaum BMI qis dua: Cov neeg Esxias Qab Teb muaj teeb meem metabolic dysfunction thiab mob siab steatotic ntawm qhov hnyav ntawm lub cev qis dua thiab qhov siab dua li cov neeg European dawb, yog li ntawd, qhov hnyav "zoo li qub" tsis suav nrog MASLD.
• Cov kab mob Hemoglobinopathies thiab cov ntshav tsis txaus hlau yog ib qho uas pom ntau hauv Is Nrias teb. Cov no tsis cuam tshuam ncaj qha rau SGPT tab sis cuam tshuam rau lwm yam kev kuaj uas feem ntau raug xaj hauv tib qho kev mus ntsib, xws li HbA1c, uas qhov kev ntseeg tau txo qis hauv thalassemia tus cwj pwm thiab lwm yam haemoglobin variants.
• Cov ntaub ntawv tiv thaiv: Yog tias koj book lossis tau txais cov ntawv qhia los ntawm lub portal online lossis app, koj cov ntaub ntawv kev noj qab haus huv yog cov ntaub ntawv tus kheej raws li Digital Personal Data Protection Act, 2023.

Tus nqi thiab kev pov hwm hauv Is Nrias teb

Kev kuaj SGPT/ALT uas ib leeg yog ib qho ntawm cov kev kuaj ntshav pheej yig tshaj plaws muaj nyob hauv Is Nrias teb, thiab feem ntau nws pheej yig dua thaum xaj hauv LFT vaj huam sib luag dua li kev kuaj ib zaug ntxiv. Cov nqi sib txawv ntawm cov nroog, ntawm cov chaw kuaj mob hauv tsev kho mob thiab cov chaw sau khoom uas ib leeg, thiab ntawm tus nqi ib leeg thiab pob khoom. Txhua tus nqi uas tau hais hauv online tsuas yog qhia xwb, paub meej tias tus nqi tam sim no ncaj qha nrog lub chaw kuaj mob ua ntej teem caij.

Cov yam uas cuam tshuam rau tus nqi:

• Txawm hais tias SGPT raug xaj ib leeg lossis hauv LFT lossis pob khoom kuaj mob
• Chaw kuaj mob hauv tsev kho mob piv rau cov saw hlau kuaj mob ib leeg piv rau chaw sau khoom
• Lub nroog thiab thaj chaw
• Cov nqi sau nqi tsev
• Kev ua haujlwm ceev lossis tom qab sijhawm ua haujlwm
• Kev lees paub ntawm lub chaw kuaj mob
• Txawm qhov kev xeem yog ib feem ntawm tsoomfwv lossis tus tswv ntiav haujlwm txoj kev npaj

Kev Pov Hwm: kev kuaj mob sab nraud feem ntau tsis them los ntawm kev pov hwm kev noj qab haus huv tus qauv tshwj tsis yog txuas nrog kev nkag mus lossis them los ntawm OPD lossis tus neeg caij tsheb kuaj mob. Thaum qhov kev kuaj mob ua tiav thaum lub sijhawm nkag mus hauv tsev kho mob, nws feem ntau suav nrog hauv qhov kev tshawb nrhiav. Tshawb xyuas koj cov nqe lus ntawm txoj cai thiab cov kev cai ua ntej kev tso cai.

Cov lus dab neeg thiab qhov tseeb

Lus nug cov lus nug

SGPT puas zoo ib yam li ALT?

Yog. SGPT (serum glutamic pyruvic transaminase) yog lub npe qub rau alanine aminotransferase. Cov chaw kuaj mob hauv Is Nrias teb feem ntau luam tawm SGPT, thaum cov ntawv qhia thoob ntiaj teb siv ALT. Cov enzyme, qhov kev ntsuam xyuas thiab lub ntsiab lus kho mob zoo ib yam, yog li tsis tas yuav rov ua qhov kev xeem yog tias koj daim ntawv qhia siv cov ntawv cim sib txawv.

SGPT siab txhais li cas?

Yog tias SGPT siab txhais tau tias cov hlwb siab tawm cov enzyme, qhia txog kev khaus lossis raug mob. Nws tsis qhia lub npe ua rau muaj qhov no. Kab mob siab steatotic, cawv, tshuaj, tshuaj ntxiv, kab mob siab viral, kab mob siab autoimmune thiab kev raug mob ntawm cov leeg nqaij yog qhov ua tau. Koj tus kws kho mob muab qhov tseem ceeb no nrog koj keeb kwm, kev kuaj mob, lwm yam kev kuaj siab thiab qee zaum kev thaij duab.

Kuv puas yuav tsum tau yoo mov ua ntej kuaj SGPT?

Feem ntau SGPT tsis tas yuav tsum yoo mov. Feem ntau yuav tsum yoo mov vim tias cov lipid profile lossis cov piam thaj hauv kev yoo mov raug sau rau tib lub sijhawm. Ua raws li cov lus qhia sau los ntawm koj lub chaw kuaj mob. Yog tias koj muaj ntshav qab zib noj tshuaj txo cov piam thaj, nug koj tus kws kho mob seb yuav noj tshuaj li cas ua ntej yoo mov.

Kuv yuav tau txais kuv qhov txiaj ntsig SGPT sai npaum li cas?

SGPT yog ib qho kev kuaj mob uas siv tshuab ua haujlwm tas li, thiab feem ntau cov chaw kuaj mob yuav tshaj tawm nws rau tib hnub ua haujlwm lossis hnub ua haujlwm tom ntej. Lub sijhawm tiag tiag nyob ntawm seb koj chav kuaj puas tau sau cov qauv, seb puas tau ua cov qauv ntawm qhov chaw lossis thauj mus rau chav kuaj mob hauv nruab nrab, thiab seb puas tau thov kom ua sai.

Puas yog SGPT tsuas yog kho tau los ntawm kev noj zaub mov thiab kev tawm dag zog xwb?

Nws nyob ntawm seb ua li cas. Hauv cov kab mob siab rog (metabolic), kev hloov pauv tas li hauv kev noj zaub mov thiab kev ua ub ua no feem ntau ua rau cov enzymes txo qis hauv ntau lub hlis. Hauv cov kab mob siab viral, kab mob siab autoimmune lossis kev raug mob los ntawm tshuaj, kev hloov pauv hauv lub neej ib leeg tsis txaus. Txhua yam kev hloov tshuaj yuav tsum yog tus kws kho mob txiav txim siab.

Puas yog SGPT siab yam tsis muaj tsos mob?

Yog, thiab qhov no yog ib qho uas tshwm sim ntau. Feem ntau pom muaj SGPT siab me ntsis ntawm daim ntawv kuaj mob rau ib tus neeg uas xav tias zoo tag nrho. Yog tias tsis muaj tsos mob tsis ua rau qhov tshwm sim tsis tseem ceeb; feem ntau nws txhais tau tias yuav tsum rov kuaj dua, nrhiav qhov ua rau thiab ntsuas qhov kev pheej hmoo ntawm fibrosis yog qhov tsim nyog.

Qhov kev kuaj twg qhia kuv seb kuv puas muaj qhov caws pliav hauv siab?

SGPT tsis tuaj yeem ntsuas qhov fibrosis. Kev ntsuas qhov tawv ntawm daim siab los ntawm kev siv elastography, cov qhab nia fibrosis uas tsis yog kev phais siv cov ntshav ntsuas, thiab qee zaum siv biopsy ntawm daim siab. Transient thiab shear-wave elastography yog cov txheej txheem sib txawv nrog cov qib sib txawv, thiab kev xaiv yog koj tus kws kho mob ua.

Vim li cas kuv tus SGPT siab tom qab kuv tawm dag zog hauv gym?

Cov leeg nqaij pob txha muaj alanine aminotransferase, yog li kev cob qhia hnyav, kev ua siab ntev lossis kev raug mob ntawm cov leeg nqaij tuaj yeem ua rau SGPT thiab SGOT nce ntxiv yam tsis muaj kab mob siab. Cov hmoov protein thiab cov tshuaj noj ua ntej kev tawm dag zog kuj tuaj yeem pab tau. Qhia rau koj tus kws kho mob txog koj qhov kev cob qhia thiab cov tshuaj noj ua ntej yuav kuaj mob siab ntxiv.

Puas yuav tsum kuaj SGPT thaum cev xeeb tub?

Yuav kuaj SGPT thaum cev xeeb tub yog tias muaj mob daj ntseg, khaus, mob plab sab saud, ntuav tas li, ntshav siab lossis xav tias muaj mob preeclampsia. Cov transaminases uas nce siab thaum cev xeeb tub tsis yog qhov kev hloov pauv ib txwm muaj thiab yuav tsum tau kuaj mob thaum cev xeeb tub, vim tias cov mob xws li cholestasis thaum cev xeeb tub thiab HELLP syndrome yuav tsum tau kho sai.

Qhov chaw

• Rinella ME et al. Cov lus pom zoo ntawm ntau lub zej zog Delphi txog kev muab lub npe tshiab rau cov kab mob siab rog (qhia txog SLD, MASLD, MASH thiab MetALD), 2023.
• Cov lus qhia kho mob ntawm American College of Gastroenterology: kev ntsuam xyuas cov tshuaj lom neeg tsis zoo hauv siab.
• Cov lus qhia txog kev kho mob ntawm European Association for the Study of the Liver txog kev siv tshuaj los kho mob siab thiab kev kuaj mob uas tsis yog kev phais rau kev ntsuam xyuas qhov hnyav ntawm kab mob siab.
• Cov ntaub ntawv qhia txog lub koom haum kev noj qab haus huv thoob ntiaj teb txog kab mob siab A, B, C thiab E.
• Cov lus pom zoo ntawm Lub Koom Haum Indian National Association for Study of the Liver (INASL) txog kev raug mob siab los ntawm tshuaj thiab kab mob siab metabolic/steatotic hauv cov neeg mob Is Nrias teb.
• Chav Haujlwm Saib Xyuas Kab Mob Ntsws Nruab Nrab, Ministry of Health and Family Welfare, cov lus qhia txog kev saib xyuas kev ua xua rau daim siab thaum lub sijhawm kho mob ntsws.
• Txoj Cai Lij Choj Txog Tshuaj thiab Kev Kho Mob Khawv Koob (Kev Tshaj Tawm Tsis Zoo), 1954; Txoj Cai Tiv Thaiv Cov Ntaub Ntawv Tus Kheej Digital, 2023.