Succimer - Uses, Dosage, Side Effects and More

Succimer, tseem hu ua DMSA (dimercaptosuccinic acid), yog ib yam tshuaj chelating uas feem ntau siv los kho cov hlau hnyav lom, tshwj xeeb tshaj yog cov hlau txhuas lom rau cov menyuam yaus. Nws ua haujlwm los ntawm kev khi rau cov hlau hnyav hauv lub cev, ua rau lawv tawm los ntawm cov zis. Succimer yog ib yam tshuaj tseem ceeb hauv kev kho mob lom, pab txo cov teebmeem tsis zoo ntawm kev sib sau ua ke ntawm cov hlau hauv lub cev.

Kev siv ntawm Succimer

Succimer tau pom zoo rau ntau yam kev siv kho mob, suav nrog:

• Lead Poisoning: Qhov qhia tseem ceeb rau succimer yog kev kho mob ntawm kev lom los ntawm cov hlau lead, tshwj xeeb tshaj yog rau cov menyuam yaus uas muaj cov ntshav txhuas ntau dua 45 micrograms ib deciliter.
• Kev lom los ntawm Mercury: Nws kuj tseem siv tsis tau daim ntawv lo rau hauv cov rooj plaub ntawm kev lom mercury, txawm hais tias qhov no tsis tshua muaj.
• Kev Lom Zem Arsenic: Succimer tuaj yeem siv tau zoo hauv kev kho mob arsenic lom.
• Lwm Cov Khoom Lom Hnyav Hlau: Nws yuav siv tau tawm ntawm daim ntawv lo rau lwm cov hlau hnyav, nyob ntawm seb kev txiav txim siab hauv kev kho mob.

Nws Ua Haujlwm Li Cas?

Succimer ua haujlwm los ntawm chelation, ib qho txheej txheem uas cov tshuaj khi rau cov hlau hnyav hauv cov ntshav. Thaum khi, cov hlau no yuav tsis ua haujlwm thiab yooj yim dua raum tawm. Hauv cov lus yooj yim dua, xav txog succimer zoo li lub hlau nplaum uas nyiam cov hlau tsis zoo, pab lub cev ntxuav lawv tawm los ntawm cov zis, yog li txo lawv cov teebmeem lom.

Dosage thiab Administration

Cov tshuaj succimer ntau npaum li cas nyob ntawm tus neeg mob lub hnub nyoog thiab qhov hnyav ntawm kev lom:

• Cov Neeg Laus: Tus nqi noj ib txwm yog 10 mg/kg noj txhua 8 teev (peb zaug hauv ib hnub) rau 5 hnub, tom qab ntawd txhua 12 teev (ob zaug hauv ib hnub) rau 14 hnub tag nrho, tsis pub tshaj 500 mg ib koob tshuaj lossis 2.5 g/hnub.
• Cov me nyuam: Rau cov menyuam yaus, cov tshuaj noj zoo sib xws: 10 mg/kg noj txhua 8 teev (peb zaug hauv ib hnub) rau 5 hnub, tom qab ntawd txhua 12 teev (ob zaug hauv ib hnub) rau 14 hnub tag nrho, tsis pub tshaj 500 mg ib koob tshuaj lossis 2.5 g/hnub.

Succimer muaj nyob rau hauv daim ntawv tshuaj ntsiav thiab yuav tsum tau noj nrog dej. Nws yog ib qho tseem ceeb kom ua raws li cov lus qhia ntawm tus kws kho mob txog kev noj tshuaj thiab lub sijhawm kho mob.

Cov Kev Mob Tshwm Sim ntawm Succimer

Cov kev mob tshwm sim ntawm succimer feem ntau suav nrog:

• xeev siab
• Ntuav
• Zawv plab
• mob plab
• Qhib

Cov kev mob tshwm sim hnyav, txawm tias tsis tshua muaj, tuaj yeem suav nrog:

• Kev tsis haum tshuaj (o, ua pa nyuaj)
• Lub siab ua haujlwm txawv txav
• Cov teeb meem ntshav (xws li thrombocytopenia)

Cov neeg mob yuav tsum tshaj tawm cov tsos mob txawv txawv rau lawv tus kws kho mob tam sim ntawd.

Tshuaj Kev Sib Thoob

Succimer tej zaum yuav cuam tshuam nrog qee cov tshuaj, suav nrog:

• Antacids: Cov no tuaj yeem txo qhov kev nqus ntawm succimer, ua rau nws tsis muaj txiaj ntsig zoo.
• Lwm yam Chelating Agents: Siv succimer nrog lwm cov chelators tuaj yeem ua rau muaj kev pheej hmoo ntawm cov kev mob tshwm sim.
• Cov Tshuaj Uas Cuam Tshuam Rau Kev Ua Haujlwm ntawm Lub Siab: Vim tias succimer raug metabolized hauv lub siab, cov tshuaj uas cuam tshuam rau cov enzymes hauv siab yuav hloov nws cov txiaj ntsig.

Qhia rau koj tus kws kho mob txog txhua yam tshuaj thiab cov tshuaj ntxiv uas koj noj kom tsis txhob muaj kev sib cuam tshuam.

Cov txiaj ntsig ntawm Succimer

Cov txiaj ntsig kho mob ntawm kev siv succimer suav nrog:

• Kev kho mob zoo: Nws yog ib qho kev kho mob uas tau ua pov thawj rau cov hlau lead thiab lwm yam kev lom hlau hnyav.
• Oral Administration: Tsis zoo li qee cov neeg sawv cev chelating uas xav tau kev txhaj tshuaj, succimer noj tau, ua rau nws yooj yim dua rau cov neeg mob, tshwj xeeb tshaj yog cov menyuam yaus.
• Safety Profile: Thaum siv raws li qhia, succimer muaj qhov profile kev nyab xeeb zoo piv rau lwm cov neeg sawv cev chelating.

Contraindications rau kev siv Succimer

Yuav tsum tsis txhob noj cov tshuaj Succimer hauv qee cov pej xeem, suav nrog:

• Cov poj niam cev xeeb tub: Kev nyab xeeb ntawm succimer thaum cev xeeb tub tsis tau tsim.
• Cov tib neeg uas muaj kab mob siab heev: Vim tias succimer metabolized hauv lub siab, cov neeg uas muaj teeb meem siab yuav tsum tsis txhob siv nws.
• Kev tsis haum: Cov neeg mob uas paub tias ua xua rau succimer lossis ib qho ntawm nws cov khoom xyaw yuav tsum tsis txhob siv cov tshuaj no.

Ceev faj thiab Kev Ceeb Toom

Ua ntej pib siv succimer, cov neeg mob yuav tsum paub txog cov hauv qab no:

• Kev kuaj lub siab ua haujlwm: Tej zaum yuav tsum tau saib xyuas lub siab ua haujlwm tas li thaum lub sijhawm kho mob.
• Kev co: Kev haus dej kom txaus yog ib qho tseem ceeb los pab cov raum tso tawm cov hlau uas khi rau hauv.
• Kev tsis haum: Ceev faj txog cov cim qhia tias koj ua xua rau tshuaj, tshwj xeeb tshaj yog thaum thawj ob peb koob tshuaj.
• Tsis tau pom zoo rau cov menyuam yaus hnub nyoog qis dua 1 xyoos vim muaj cov ntaub ntawv tsawg.

FAQ

• Succimer siv rau dab tsi? Succimer feem ntau yog siv los kho cov tshuaj lom txhuas thiab lwm yam tshuaj lom hlau hnyav.
• Yuav noj succimer li cas? Succimer noj tau hauv daim ntawv tshuaj ntsiav, feem ntau nrog dej.
• Cov kev mob tshwm sim ntawm succimer yog dab tsi? Cov kev mob tshwm sim feem ntau muaj xws li xeev siab, ntuav, thiab mob plab. Cov kev mob tshwm sim loj heev tuaj yeem tshwm sim tab sis tsis tshua muaj.
• Puas siv tau succimer rau menyuam yaus? Yog, succimer tau pom zoo rau kev siv rau menyuam yaus, tshwj xeeb tshaj yog rau kev lom los ntawm cov hlau lead.
• succimer ua haujlwm li cas? Succimer khi rau cov hlau hnyav hauv lub cev, cia lawv raug tso tawm los ntawm cov zis.
• Puas muaj kev sib cuam tshuam ntawm cov tshuaj nrog succimer? Yog, succimer tuaj yeem cuam tshuam nrog antacids thiab lwm yam tshuaj uas cuam tshuam rau kev ua haujlwm ntawm daim siab.
• Puas yog succimer muaj kev nyab xeeb thaum cev xeeb tub? Tsis pom zoo kom siv Succimer thaum cev xeeb tub vim tsis muaj cov ntaub ntawv txaus txog kev nyab xeeb.
• Kuv yuav ua li cas yog tias kuv tsis noj tshuaj? Yog tias koj tsis nco qab noj ib koob tshuaj, noj sai li sai tau thaum koj nco qab tsuas yog tias nws yuav luag txog lub sijhawm noj koob tshuaj tom ntej; tsis txhob noj ob zaug xwb.
• Kev kho mob nrog succimer ntev npaum li cas? Feem ntau, 19 hnub (5 hnub ntawm TID, 14 hnub ntawm BID), nrog rau qhov ua tau rov ua dua cov chav kawm tom qab 2 lub lis piam yog tias cov tshuaj lead tseem siab.
• Kuv puas noj tau succimer nrog lwm yam tshuaj? Nco ntsoov nrog koj tus kws kho mob tham ua ntej noj succimer nrog lwm yam tshuaj kom tsis txhob muaj kev sib cuam tshuam.

Hom Lub Npe

Succimer raug muag hauv Chemet.

xaus

Succimer yog ib yam tshuaj tseem ceeb heev rau kev kho mob ntawm cov hlau hnyav lom, tshwj xeeb yog cov hlau txhuas. Nws lub peev xwm los chelate cov hlau tsis zoo thiab pab txhawb lawv cov zis ua rau nws yog ib qho cuab yeej tseem ceeb hauv kev lom tshuaj. Txawm hais tias feem ntau muaj kev nyab xeeb, nws yog ib qho tseem ceeb uas yuav tsum siv succimer nyob rau hauv kev saib xyuas ntawm kws kho mob kom saib xyuas cov kev mob tshwm sim thiab kev sib cuam tshuam. Ib txwm sab laj nrog koj tus kws kho mob kom tau txais cov lus qhia thiab kev kho mob.