Thioridazine - Siv, Li Noj, Cov Kev Mob Tshwm Sim thiab Ntau Ntxiv

Kev Taw Qhia: Thioridazine yog dab tsi?

Thioridazine yog ib hom tshuaj tiv thaiv kev puas siab puas ntsws uas feem ntau siv los kho tus mob schizophrenia thiab lwm yam kev puas siab puas ntsws. Nws yog ib hom tshuaj hu ua phenothiazines, uas ua haujlwm los ntawm kev cuam tshuam rau qhov sib npaug ntawm qee cov tshuaj hauv lub hlwb. Thioridazine paub txog nws cov khoom ua rau tsaug zog thiab feem ntau raug sau tseg thaum lwm yam kev kho mob tsis tau zoo.

Kev siv ntawm Thioridazine

Thioridazine feem ntau yog pom zoo rau kev kho mob schizophrenia, uas yog ib qho mob hlwb uas muaj kev xav tsis thoob, pom kev tsis meej, thiab xav tsis meej. Nws kuj tseem siv tau rau lwm yam mob, xws li kev ntxhov siab lossis kev ntxhov siab heev, tshwj xeeb tshaj yog rau cov neeg mob uas tsis teb zoo rau lwm yam tshuaj tiv thaiv kev puas siab puas ntsws, txawm tias tsis tshua muaj hnub no vim muaj cov lus ceeb toom dub.

Nws Ua Haujlwm Li Cas?

Thioridazine ua haujlwm los ntawm kev thaiv cov dopamine receptors hauv lub hlwb, tshwj xeeb tshaj yog D2 subtype. Dopamine yog ib qho neurotransmitter uas ua lub luag haujlwm tseem ceeb hauv kev xav, kev coj cwj pwm, thiab kev paub. Los ntawm kev txwv tsis pub dopamine ua haujlwm, Thioridazine pab txo cov tsos mob ntawm kev puas siab puas ntsws, xws li kev pom tsis tseeb thiab kev dag ntxias, ua rau lub hlwb ruaj khov thiab ua haujlwm tau zoo dua.

Dosage thiab Administration

Tus qauv tshuaj ntawm Thioridazine sib txawv raws li tus neeg mob thiab kev teb rau kev kho mob. Rau cov neeg laus, qhov pib koob tshuaj yog 50 mg txog 100 mg noj, feem ntau yog faib ua ntau koob tshuaj thoob plaws hnub. Qhov siab tshaj plaws txhua hnub yuav tsum tsis pub tshaj 800 mg (feem ntau capped ntawm ?600 mg / hnub vim muaj kev pheej hmoo QT). Kev siv rau menyuam yaus feem ntau yog zam vim muaj kev pheej hmoo ntawm lub plawv; keeb kwm dosed los ntawm qhov hnyav yog tias xav txog. Thioridazine muaj nyob rau hauv daim ntawv ntsiav tshuaj thiab yuav tsum tau noj nrog zaub mov kom txhim kho kev nqus.

Cov Kev Mob Tshwm Sim ntawm Thioridazine

Cov kev mob tshwm sim ntawm Thioridazine feem ntau muaj xws li:

• Tsaus ntuj
• Kauj taub hau
• qhov ncauj qhuav
• Qhov muag plooj tsis pom kev
• cem quav
• Late dyskinesia
• Cov tsos mob extrapyramidal (piv txwv li, parkinsonism)

Cov kev mob tshwm sim hnyav tuaj yeem suav nrog:

• Cov teeb meem plawv atherosclerosis (QT prolongation)
• Kev tsis haum tshuaj heev
• Neuroleptic malignant syndrome (ib yam mob uas ua rau tuag taus)
• Cov teeb meem ntshav (xws li agranulocytosis, saib xyuas los ntawm kev suav cov ntshav)

Cov neeg mob yuav tsum tshaj tawm cov tsos mob txawv txawv rau lawv tus kws kho mob tam sim ntawd.

Tshuaj Kev Sib Thoob

Thioridazine tuaj yeem cuam tshuam nrog ntau yam tshuaj thiab tshuaj, suav nrog:

• Lwm cov tshuaj tiv thaiv kev puas siab puas ntsws
• antidepressants
• Cov tshuaj uas cuam tshuam rau lub plawv dhia
• Cov tshuaj CYP2D6 uas muaj zog heev (piv txwv li, fluoxetine, paroxetine)
• Cawv thiab tshuaj ua si

Nws yog ib qho tseem ceeb kom qhia rau koj tus kws kho mob txog txhua yam tshuaj thiab cov tshuaj uas koj noj kom tsis txhob muaj kev cuam tshuam.

Cov txiaj ntsig ntawm Thioridazine

Thioridazine muaj ntau yam kev pab kho mob, xws li:

• Kev tswj hwm zoo ntawm cov tsos mob ntawm tus mob schizophrenia
• Cov teebmeem sedative uas tuaj yeem pab nrog kev ntxhov siab
• Keeb kwm zoo ntawm kev siv hauv kev kho mob puas siab puas ntsws

Rau qee tus neeg mob, Thioridazine yuav yog ib qho kev xaiv tsim nyog thaum lwm cov tshuaj antipsychotic tsis ua haujlwm.

Cov kev tsis sib haum xeeb ntawm Thioridazine

Qee tus neeg yuav tsum tsis txhob siv Thioridazine, xws li:

• Cov poj niam cev xeeb tub los yog pub niam mis
• Cov neeg mob uas muaj keeb kwm ntawm teeb meem plawv, tshwj xeeb tshaj yog arrhythmias
• Cov tib neeg uas muaj kab mob siab lossis mob raum hnyav
• Cov neeg uas muaj kev tsis haum tshuaj rau Thioridazine lossis lwm yam phenothiazines
• Siv ua ke nrog lwm cov tshuaj QT-prolonging; Keeb kwm ntawm QT ntev.

Lus Cim: Thioridazine raug rho tawm ntawm kev lag luam hauv Tebchaws Meskas xyoo 2005 vim muaj kev pheej hmoo ntawm lub plawv; tsis tau muaj nyob hauv ntau lub tebchaws. Kev sab laj nrog tus kws kho mob yog qhov tseem ceeb ua ntej pib siv cov tshuaj no.

Ceev faj thiab Kev Ceeb Toom

Ua ntej siv Thioridazine, cov neeg mob yuav tsum tau kuaj xyuas kom zoo. Kev saib xyuas lub plawv tsis tu ncua yuav tsum tau ua vim muaj kev pheej hmoo ntawm QT ntev. Yuav tsum tau kuaj ECG thiab kev saib xyuas tsis tu ncua rau QTc > 500 ms; tsis pom zoo rau cov menyuam yaus / cov hluas ib daim ntawv lo niaj hnub. Cov neeg mob uas muaj keeb kwm ntawm qaug dab peg, ntshav qab zib, lossis lwm yam teeb meem kev noj qab haus huv tseem ceeb yuav tsum tham txog cov mob no nrog lawv tus kws kho mob.

FAQ

1. Kuv yuav tsum ua li cas yog tias kuv tsis nco qab noj Thioridazine?

Yog koj tsis nco qab noj ib zaug, noj sai li sai tau thaum koj nco qab. Yog tias yuav luag txog lub sijhawm noj tshuaj tom ntej, hla qhov noj tshuaj uas koj tsis nco qab thiab ua raws li koj lub sijhawm ib txwm. Tsis txhob noj ob zaug.

2. Kuv puas haus tau cawv thaum noj Thioridazine?

Nws yog ib qho tsim nyog kom tsis txhob haus dej cawv, vim nws tuaj yeem ua rau cov teebmeem sedative ntawm Thioridazine ntau ntxiv thiab tej zaum yuav ua rau muaj kev phiv tshuaj txaus ntshai.

3. Nws siv sijhawm ntev npaum li cas rau Thioridazine ua haujlwm?

Tej tus neeg mob yuav pom tias lawv zoo dua li ob peb hnub, tiam sis tej zaum yuav siv sij hawm ob peb lub lis piam mam li pom tau tag nrho cov txiaj ntsig ntawm cov tshuaj no.

4. Thioridazine puas siv tau ntev?

Kev siv mus sij hawm ntev yuav tsum tau saib xyuas zoo los ntawm tus kws kho mob vim tias muaj tej yam tshwm sim tsis zoo, suav nrog kev txav mus los tsis zoo.

5. Thioridazine puas ua rau hnyav nce?

Qhov hnyav nce yog qhov tshwm sim ntawm Thioridazine, thiab cov neeg mob yuav tsum tham txog txhua yam kev txhawj xeeb nrog lawv tus kws kho mob.

6. Kuv yuav tsum ua li cas yog tias kuv ntsib cov kev mob tshwm sim?

Hu rau koj tus kws kho mob tam sim ntawd yog tias koj muaj cov kev mob tshwm sim loj heev lossis muaj cov tsos mob txawv txawv.

7. Siv tau Thioridazine rau menyuam yaus?

Thioridazine tsis raug siv rau cov menyuam yaus thiab cov hluas vim muaj kev pheej hmoo ntawm QT ntev (FDA lub thawv dub ceeb toom).

8. Thioridazine puas yuav cuam tshuam rau kuv lub peev xwm tsav tsheb?

Thioridazine tuaj yeem ua rau tsaug zog thiab kiv taub hau, yog li nws tseem ceeb heev uas yuav tsum ntsuam xyuas seb koj xav li cas ua ntej tsav tsheb lossis siv cov tshuab hnyav.

9. Kuv puas tso tseg tau Thioridazine tam sim ntawd?

Tsis txhob tsum tsis txhob noj Thioridazine sai sai yam tsis tau sab laj nrog koj tus kws kho mob, vim qhov no tuaj yeem ua rau muaj cov tsos mob rho tawm lossis rov qab los ntawm koj tus mob.

10. Puas muaj kev pheej hmoo ntawm kev quav tshuaj rau Thioridazine?

Thioridazine tsis suav tias yog kev quav tshuaj uas tsis muaj peev xwm ua phem, tab sis nws yuav tsum siv raws li tau teev tseg kom tsis txhob muaj teeb meem.

Hom Lub Npe

Thioridazine muaj ntau lub npe lag luam, suav nrog Mellaril thiab Thioridazine HCl.

xaus

Thioridazine muaj nqis keeb kwm tab sis feem ntau hloov vim muaj kev txhawj xeeb txog kev nyab xeeb hauv kev kho mob schizophrenia thiab lwm yam kev mob hlwb. Txawm hais tias nws muaj txiaj ntsig zoo, nws yog qhov tseem ceeb rau cov neeg mob kom paub txog cov kev mob tshwm sim, kev sib cuam tshuam ntawm cov tshuaj, thiab cov kev tsis pom zoo. Kev sib txuas lus tsis tu ncua nrog cov kws kho mob yog qhov tseem ceeb kom ntseeg tau tias siv cov tshuaj no kom muaj kev nyab xeeb thiab zoo.