Daclatasvir - Siv, Li Noj, Cov Kev Mob Tshwm Sim thiab Ntau Ntxiv

Kev Taw Qhia: Daclatasvir yog dab tsi?

Daclatasvir yog ib hom tshuaj tua kab mob uas siv los kho tus kab mob siab C (HCV). Nws yog ib hom tshuaj uas hu ua direct-acting antivirals (DAAs), uas tsom mus rau cov kauj ruam tshwj xeeb hauv lub neej ntawm HCV kom tiv thaiv tus kab mob kom rov ua dua. Daclatasvir feem ntau siv ua ke nrog lwm cov tshuaj tua kab mob kom txhim kho nws cov txiaj ntsig thiab txhim kho cov txiaj ntsig kev kho mob rau cov neeg mob uas muaj kab mob siab C.

Kev siv ntawm Daclatasvir

Daclatasvir tau txais kev pom zoo rau kev kho mob hepatitis C ntev rau cov neeg laus. Nws muaj txiaj ntsig zoo rau qee hom kab mob, suav nrog genotype 1, 2, 3, thiab 4. Cov tshuaj no feem ntau siv ua ke nrog lwm cov tshuaj tua kab mob, xws li sofosbuvir, los muab txoj hauv kev kom tshem tawm cov kab mob ntawm lub cev. Kev kho mob ua ke no tau pom tias ua rau muaj kev teb virologic (SVR) tas mus li, uas txhais tau tias tus kab mob tsis pom hauv cov ntshav tom qab kho.

Yuav ua li cas Nws Tej hauj lwm

Daclatasvir ua haujlwm los ntawm kev txwv tsis pub muaj ib hom protein hu ua NS5A, uas yog qhov tseem ceeb rau kev sib sau ua ke thiab kev sib kis ntawm tus kab mob hepatitis C. Los ntawm kev thaiv cov protein no, Daclatasvir tiv thaiv tus kab mob kom tsis txhob loj hlob thiab kis mus rau hauv lub cev. Hauv cov lus yooj yim dua, koj tuaj yeem xav txog Daclatasvir zoo li lub xauv uas haum rau hauv lub qhov tseem ceeb, tiv thaiv tus kab mob kom tsis txhob qhib lub qhov rooj rau kev kis kab mob thiab kev sib kis ntxiv.

Dosage thiab Administration

Tus qauv noj tshuaj Daclatasvir rau cov neeg laus feem ntau yog 60 mg noj ib zaug ib hnub, nrog lossis tsis noj mov. Rau cov menyuam yaus, qhov ntau npaum li cas yuav txawv raws li hnub nyoog thiab qhov hnyav, thiab nws yog ib qho tseem ceeb uas yuav tsum ua raws li cov lus qhia ntawm tus kws kho mob. Daclatasvir muaj nyob rau hauv daim ntawv ntsiav tshuaj, ua rau nws yooj yim rau kev siv. Nws yog ib qho tseem ceeb uas yuav tsum noj tshuaj tas li tib lub sijhawm txhua hnub kom tswj tau cov qib zoo hauv cov ntshav.

Cov Kev Mob Tshwm Sim ntawm Daclatasvir

Ib yam li txhua yam tshuaj, Daclatasvir tuaj yeem ua rau muaj kev phiv. Cov kev phiv feem ntau muaj xws li:

• nkees nkees
• Mob taub hau
• xeev siab
• Zawv plab
• insomnia

Kev mob tshwm sim hnyav, txawm tias tsawg dua, tuaj yeem suav nrog:

• Cov teeb meem hauv siab (siab siab enzymes)
• Kev tsis haum tshuaj (pob liab, khaus, o)
• Mob hnyav lossis qaug zog

Cov neeg mob yuav tsum tshaj tawm tej yam txawv txav los yog mob hnyav rau lawv tus kws kho mob tam sim ntawd.

Tshuaj Kev Sib Thoob

Daclatasvir muaj peev xwm sib cuam tshuam nrog ntau yam tshuaj, uas yuav cuam tshuam rau nws txoj kev ua haujlwm lossis ua rau muaj kev pheej hmoo ntawm cov kev mob tshwm sim. Kev sib cuam tshuam loj ntawm cov tshuaj suav nrog:

• Cov tshuaj tiv thaiv kev qaug dab peg (piv txwv li, carbamazepine, phenytoin)
• Rifampin (ib qho tshuaj tua kab mob)
• St. John's Wort (ib yam tshuaj ntsuab ntxiv)
• Qee cov tshuaj kho mob HIV (piv txwv li, cov tshuaj protease inhibitors)

Nws yog ib qho tseem ceeb rau cov neeg mob qhia lawv tus kws kho mob txog txhua yam tshuaj, tshuaj, thiab tshuaj ntsuab uas lawv noj kom tsis txhob muaj kev cuam tshuam.

Cov txiaj ntsig ntawm Daclatasvir

Kev siv Daclatasvir hauv kev kho mob hepatitis C muaj ntau yam zoo hauv kev kho mob:

• Cov nqi ua tau zoo heev: Daclatasvir, tshwj xeeb tshaj yog ua ke nrog lwm cov tshuaj tua kab mob, tau pom tias muaj cov nqi SVR siab.
• Lub sijhawm kho mob luv dua: Ntau tus neeg mob tuaj yeem kho tau hauv 12 lub lis piam ntawm kev kho mob.
• Cov kev mob tshwm sim tsawg dua: Piv rau cov kev kho mob hepatitis C qub, Daclatasvir feem ntau muaj cov kev mob tshwm sim zoo dua.
• Kev noj tshuaj: Kev yooj yim ntawm kev noj tshuaj ib zaug ib hnub ua rau kev ua raws li kev kho mob zoo dua.

Contraindications ntawm Daclatasvir

Ib txhia neeg yuav tsum tsis txhob siv Daclatasvir, xws li:

• Cov poj niam cev xeeb tub: Tsis tau nkag siab tag nrho txog cov teebmeem ntawm Daclatasvir rau kev loj hlob ntawm tus menyuam hauv plab, yog li nws raug qhia kom tsis txhob siv thaum cev xeeb tub.
• Cov neeg mob uas muaj kab mob siab hnyav: Cov neeg uas muaj kab mob cirrhosis lossis lub siab puas tsuaj loj heev yuav tsum tsis txhob siv Daclatasvir yam tsis tau kev saib xyuas los ntawm kws kho mob.

Ceev faj thiab Kev Ceeb Toom

Ua ntej pib siv Daclatasvir, cov neeg mob yuav tsum tau kuaj xyuas lawv lub siab kom paub tseeb tias lawv lub siab noj qab haus huv zoo. Nws tseem ceeb heev uas yuav tsum tham txog keeb kwm ntawm kab mob siab, kev ua xua, lossis lwm yam mob nrog tus kws kho mob. Kev saib xyuas tsis tu ncua thaum lub sijhawm kho mob yuav tsum tau ua kom ntseeg tau tias cov tshuaj ua haujlwm tau zoo thiab tswj hwm cov kev mob tshwm sim.

FAQ

1. Daclatasvir siv rau dab tsi? Daclatasvir siv los kho tus kab mob siab C ntev, feem ntau siv ua ke nrog lwm cov tshuaj tua kab mob.
2. Kuv yuav tsum noj Daclatasvir li cas? Noj Daclatasvir raws li koj tus kws kho mob tau hais, feem ntau yog 60 mg ib zaug ib hnub, nrog lossis tsis noj mov.
3. Cov kev phiv tshwm sim yog dab tsi? Cov kev mob tshwm sim feem ntau suav nrog qaug zog, mob taub hau, xeev siab, raws plab, thiab pw tsis tsaug zog.
4. Kuv puas noj tau Daclatasvir yog tias kuv cev xeeb tub? Tsis pom zoo rau cov poj niam cev xeeb tub vim muaj kev pheej hmoo rau tus menyuam hauv plab.
5. Daclatasvir ua haujlwm li cas? Daclatasvir tiv thaiv cov protein tseem ceeb rau kev tsim cov kab mob siab C, tiv thaiv nws kom tsis txhob loj hlob.
6. Puas muaj kev phiv loj heev? Cov kev mob tshwm sim loj heev tuaj yeem suav nrog teeb meem siab thiab kev ua xua. Qhia txog cov tsos mob hnyav rau koj tus kws kho mob.
7. Kuv yuav ua li cas yog tias kuv tsis noj tshuaj? Yog tias koj tsis noj tshuaj, noj sai li sai tau thaum koj nco qab. Yog tias nws nyob ze rau qhov koob tshuaj tom ntej, hla qhov koob tshuaj uas tsis tau thiab txuas ntxiv koj lub sijhawm.
8. Kuv puas haus tau cawv thaum noj Daclatasvir? Nws yog ib qho zoo kom tsis txhob haus dej cawv lossis tsis txhob haus, vim nws tuaj yeem ua rau lub siab tsis zoo.
9. Kuv yuav tsum noj Daclatasvir ntev npaum li cas? Feem ntau lub sijhawm kho mob yuav kav ntev li 12 lub lis piam, tab sis koj tus kws kho mob yuav txiav txim siab qhov ntev npaum li cas raws li koj tus mob.
10. Daclatasvir puas kho kuv tus kab mob siab C? Muaj ntau tus neeg mob uas muaj cov kab mob virologic teb tau zoo, uas txhais tau tias tsis pom tus kab mob tom qab kho tas, uas suav tias yog kev kho tau zoo.

Hom Lub Npe

Daclatasvir muaj ntau hom tshuaj, xws li:

• Daklinza
• Daclahep
• Daclinza

xaus

Daclatasvir yog ib yam tshuaj tseem ceeb heev rau kev tiv thaiv kab mob siab C ntev, muab cov kev kho mob zoo nrog rau kev nyab xeeb zoo. Nws lub peev xwm los tiv thaiv kev sib kis ntawm tus kab mob ua rau nws yog ib qho tseem ceeb hauv kev kho mob ua ke, ua rau muaj kev kho mob zoo. Cov neeg mob uas xav noj Daclatasvir yuav tsum sab laj nrog lawv tus kws kho mob kom nkag siab txog nws cov txiaj ntsig, cov kev mob tshwm sim, thiab qhov tseem ceeb ntawm kev ua raws li kev kho mob uas tau sau tseg.