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    Bone Marrow Transplantation (Autologous And Allogeneic)
    Banner - Cancer Institute Apollo Hospital - Bangalore

    Bone Tumours Treatment in Bangalore

    Bone Marrow, a spongy mass of tissue found in the centre of bones, is responsible for producing healthy Erythrocytes (Red Blood Cells), Leukocytes (White Blood Cells), and Thrombocytes (Platelets). Bone marrow is one of the most essential elements in the human body to sustain life in general and for the proper functioning of the body. Sometimes, diseases and disorders may affect the bone marrow causing it to make abnormal cells or in abnormal amounts. In other cases, certain cancer treatments, such as radiation therapy, may destroy or damage healthy bone marrow, making it lose the ability to produce healthy blood cells.

    In such cases, bone marrow transplantation is necessary. Apollo Hospitals, Karnataka, offers all-inclusive diagnostic, treatment, and surgical expertise and support to cure a wide range of blood disorders associated with bone marrow and/or post-cancer treatment rehabilitation with corrective surgeries caused by certain treatments.

    How does Bone Marrow Transplantation work?

    In bone marrow transplantation (BMT), healthy blood-forming cells are taken from a donor or from the patient itself to replace the damaged bone marrow in the patient. Before transplantation, the blood from the donor is screened and matched with the donor’s blood type and various other factors to avoid any complications. The blood-forming cells thus retrieved are infused into the bloodstream of the patient, where those cells may begin to grow and produce healthy WBCs, RBCs, and platelets.

    Does Bone Marrow Transplantation hurt?

    Although the donated blood cells are received through intravenous administration, the process itself doesn’t hurt. The patient may stay awake or sleep during the procedure and may feel that it is like taking medicine or other solutions through the IV.

    Types of Bone Marrow Transplantation

    Bone marrow transplantation is usually performed in two ways as may be suitable for the patient depending on the individual condition and needs.

    1. Autologous Transplantation

    In autologous bone marrow transplantation, the bone marrow is collected from the patient himself, which is then harvested for later use. The bone marrow cells are usually collected when cancer is in remission or has been stabilised. Patients undergo conditioning therapy before transplantation, where the patient’s bone marrow may get destroyed. This damaged bone marrow is replaced by the stored cells, which are inserted into the patient through an IV channel. These bone marrow cells may then grow into new bone marrow cells to replace the ones destroyed by chemotherapy.

    1. Allogeneic Transplantation

    In allogeneic bone marrow transplantation, the bone marrow cells are received from a donor who is a good genetic match for the patient. Before transplantation, extensive DNA testing and analysis are performed to ensure that the donor’s bone marrow will be a good match for the patient. The patient may receive conditioning therapy before the allogeneic transplantation of bone marrow cells, and then the cells are infused into the patient’s bloodstream, just like a blood transfusion.

    For allogeneic transplantation, siblings of the patients are the best match for the patient. However, if the patient doesn’t have any siblings, bone marrow from an unrelated donor may also be utilised. In such a case, each donor is thoroughly evaluated to find the perfect match for the patient. Even if the donor may not be a perfect match for the patient, bone marrow transplantation may be the best option for treatment for the patient.

    How to Prepare for Bone Marrow Transplantation?

    There are many steps involved before a bone marrow transplantation is done, which include screening and testing of both the patient and the donor. Pre-transplantation tests and screening are performed with utmost importance at Apollo Hospitals, Karnataka, as it may significantly affect the patient receiving the bone marrow cells.

    First, the patient may be tested thoroughly to determine if he is fit to receive the transplant. Then conditioning therapy may be performed to ensure the patient’s physical condition is in a state to accept the transplant and to destroy any remnant cancer cells. This step may be performed using high-dose chemotherapy, and sometimes radiation therapy may also be accompanied for destroying any residual cancer cells.

    The duration of time required for transplantation therapy may vary depending on the individual conditions of the patient. After this therapy is complete, the patient is ready to receive a bone marrow transplant.

    Apollo Hospitals, Karnataka, is a centre of excellence for cancer and various blood disorder care for patients of all ages. We are committed to providing the highest quality of diagnostic, treatment, and patient care services, along with a special focus on rehabilitation to ensure holistic management of diseases and disorders. We at Apollo Hospitals, Karnataka, adopt a multidisciplinary approach consisting of Oncologists, Pathologists, Radiologists, Haematologists, and other medical specialists and professionals to provide a one-stop, comprehensive solution for all kinds of blood disorders and cancer.

    We use state-of-the-art, high-end surgical and diagnostic equipment for diagnostic and treatment purposes of numerous cancer and blood disorders so that treatment is as pain-free as possible. Physiotherapy experts and psychotherapy specialists work in close collaboration with the patients to help them recover smoothly and lead a healthy life afterwards.

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