Testosterone

Isingeniso: Kuyini i-Testosterone?

I-Testosterone iyi-hormone ebalulekile ekhiqizwa kakhulu emasendeni kwabesilisa kanye nangobuningi obuncane emaqanda kwabesifazane. Idlala indima ebalulekile ekuthuthukisweni kwezici zomzimba zabesilisa, njengemisipha, ukuqina kwamathambo, kanye nezinwele zomzimba. Ngaphandle kwendima yayo ekuthuthukisweni kocansi, i-testosterone ibalulekile empilweni iyonke, ithonya isimo sengqondo, amazinga amandla, ngisho nokusebenza kwengqondo.

Ukusetshenziswa kwe-Testosterone

I-Testosterone ivunyelwe ukusetshenziswa kwezokwelapha eziningana, okuhlanganisa:

• I-Hypogonadism: Isimo lapho umzimba ungakhiqizi khona i-testosterone eyanele, okuholela ezimpawini ezifana nokukhathala, ukucindezeleka kanye nokuncipha kwesifiso sobulili.
• Ukuthomba Okubambezelekile: Kubafana abangakaqali ukuthomba lapho beneminyaka eyi-14, i-testosterone ingasiza ekuqaliseni ukuthuthukiswa kwezici zobulili zesibili.
• I-Hormone Replacement Therapy (HRT): Kwabesilisa abanamazinga aphansi e-testosterone ngenxa yokuguga noma ezinye izinkinga zempilo.
• Izinhlobo Ezithile Zomdlavuza Webele: Isetshenziswe ngokomlando ekwelapheni umdlavuza webele osezingeni eliphezulu kwabesifazane (akuvamile manje ngenxa yezinketho ezingcono kakhulu).

Isebenza kanjani?

I-Testosterone isebenza ngokubopha kuma-receptor e-androgen ezicutshini ezahlukahlukene emzimbeni wonke. Lokhu kubopha kubangela uchungechunge lwezinqubo zebhayoloji eziholela ekuthuthukisweni kwezici zesilisa kanye nokugcinwa kwemisebenzi ehlukahlukene yomzimba. Kalula nje, i-testosterone isebenza njengesihluthulelo esivula amandla okukhula nokuthuthuka emisipheni, emathanjeni, nakwezinye izicubu.

Isilinganiso nokuphathwa

Umthamo we-testosterone uyahlukahluka kuye ngesimo eselashwayo kanye nohlobo lwe-testosterone esetshenziswayo. Izinhlobo ezivamile zifaka:

• I-Testosterone Ejovwayo: Ngokuvamile inikezwa njalo ngemva kwesonto elilodwa kuya kwamabili, ngemithamo esukela ku-50 kuya ku-400 mg, kuye ngezidingo zomuntu ngamunye.
• Ama-Patches e-Transdermal: Kusetshenziswa nsuku zonke, kunikeza umthamo ozinzile we-testosterone, ngokuvamile cishe u-2 kuya ku-4 mg ngosuku.
• AmaGel: Isetshenziswa esikhumbeni nsuku zonke, ngemithamo evame ukuba phakathi kuka-25 no-100 mg ngosuku.

Imithamo yezingane inqunywa ngumhlinzeki wezempilo ngokusekelwe ezidingweni ezithile zengane.

Imiphumela Engemihle Ye-Testosterone

Imiphumela emibi evamile yokwelashwa kwe-testosterone ingafaka:

• Izinduna noma isikhumba esinamafutha
• Ukulahlekelwa izinwele noma ukwanda kwezinwele zomzimba
• Ukushintshashintsha kwemizwa noma ukucasuka
• I-apnea yokulala
• Inani lamaseli abomvu egazi elandayo

Imiphumela emibi kakhulu ingabandakanya:

• Izinkinga zenhliziyo (isb., ukuhlaselwa yinhliziyo, isifo sohlangothi)
• Ukulimala kwesibindi
• Ukwanda kwe-prostate; ukusheshisa ukukhula komdlavuza we-prostate okhona
• Ama-clots egazi

Ukusebenzisana kwezidakamizwa

I-Testosterone ingasebenzisana nemithi eminingana nezinto, okuhlanganisa:

• Ama-anticoagulants: Njenge-warfarin, engandisa ingozi yokopha.
• I-insulin: I-Testosterone ingase yehlise amazinga kashukela egazini, okudinga ukulungiswa komthamo we-insulin.
• I-Corticosteroids: Ukusetshenziswa ngasikhathi sinye kungandisa ingozi yokuvuvukala.

Njalo yazisa umhlinzeki wakho wezempilo ngayo yonke imithi kanye nezithasiselo ozithathayo.

Izinzuzo ze-Testosterone

Izinzuzo zezokwelapha zokwelashwa kwe-testosterone zifaka:

• Amazinga wamandla athuthukisiwe kanye nesimo sengqondo
• Ukwanda kwemisipha namandla
• I-libido ethuthukisiwe nomsebenzi wocansi
• Ukuqina kwamathambo okungcono, kunciphisa ingozi yokuqhekeka kwamathambo
• Ukusebenza kwengqondo okuthuthukisiwe kanye nenkumbulo

Izimo ze-Testosterone

Abantu abathile kufanele bagweme ukwelashwa kwe-testosterone, okuhlanganisa:

• Abesifazane abakhulelwe, njengoba kungalimaza ukukhula kwengane.
• Abantu abanomdlavuza we-prostate noma webele.
• Labo abanesifo esibi sesibindi noma sezinso.
• Amadoda anezibalo eziphezulu zamaseli abomvu egazi (i-polycythemia).

Ukuqapha Nezexwayiso

Ngaphambi kokuqala ukwelashwa kwe-testosterone, iziguli kufanele zihlolwe ngokuphelele, okuhlanganisa:

• Ukuhlolwa kwegazi ukuhlola amazinga ama-hormone kanye nempilo iyonke.
• Ukuqapha impilo ye-prostate, ikakhulukazi kwabesilisa asebekhulile.
• Ukulandelela njalo ukuhlola ukusebenza kahle kanye nemiphumela emibi yokwelashwa.

Imibuzo Evame Ukubuzwa

• Kuyini ukwelashwa kwe-testosterone? Ukwelashwa nge-testosterone kuhilela ukunikeza i-testosterone ukwelapha amazinga aphansi e-hormone, ukuthuthukisa izimpawu ezifana nokukhathala kanye nesifiso sokudla esiphansi.
• Ubani ongazuza ekwelashweni kwe-testosterone? Amadoda ane-hypogonadism noma amazinga aphansi e-testosterone, kanye nabanye besifazane abanezimo ezithile zezokwelapha, bangazuza.
• I-testosterone inikezwa kanjani? I-Testosterone inganikezwa ngemijovo, ama-patches, ama-gel, noma ama-pellet afakwe ngaphansi kwesikhumba.
• Yiziphi imiphumela emibi ye-testosterone? Imiphumela emibi evamile ihlanganisa induna, ukushintsha kwemizwa, kanye nokukhula kwezinwele okwandisiwe. Izingozi ezinkulu zifaka phakathi izinkinga zenhliziyo kanye nokulimala kwesibindi.
• Ingabe ukwelashwa kwe-testosterone kungathinta ukuzala? Yebo, ukwelashwa nge-testosterone kunganciphisa ukukhiqizwa kwesidoda, okungase kuthinte ukuzala kwabesilisa.
• Ingabe ukwelashwa kwe-testosterone kuphephile kubantu abadala? Kungaphephile kodwa kudinga ukuqapha ngokucophelela ngenxa yezingozi ezingaba khona njengesifo senhliziyo nezinkinga ze-prostate.
• Kuthatha isikhathi esingakanani ukubona imiphumela yokwelashwa kwe-testosterone? Iziguli eziningi ziyabona ukuthuthuka kwamandla kanye nemizwa zingakapheli amasonto ambalwa, kuyilapho izinguquko zomzimba zingathatha izinyanga eziningana.
• Ingabe abesifazane bangathatha i-testosterone? Yebo, kodwa akuvamile; i-testosterone ephansi ingasetshenziswa ngaphandle kwelebula lokuphazamiseka kwesifiso sobulili okungenamandla kwabesifazane asebedlulile esikhathini sokuya esikhathini, ngaphansi kokuqashwa okuseduze.
• Yini okufanele ngiyenze uma ngiphuthelwa umthamo? Uma uphuthelwa umthamo, thatha ngokushesha lapho ukhumbula. Uma kuseduze nomthamo olandelayo, yeqa umthamo futhi uqhubeke nohlelo lwakho.
• Ingabe izinguquko zendlela yokuphila zingasiza nge-testosterone ephansi? Yebo, ukugcina ukudla okunempilo, ukuvivinya umzimba njalo, kanye nokulawula ukucindezeleka kungaba nomthelela omuhle emazingeni e-testosterone.

Amagama Omkhiqizo

Amanye amagama amakhulu e-testosterone afaka phakathi (izibonelo; ukutholakala kuyahlukahluka ngokwesifunda, isib., i-Depo-Testosterone evamile ejovwayo, i-Testopel yama-pellets):

• I-AndroGel
• Fakaza
• I-Depo-Testosterone
• I-Axiron
• Fortesta
• I-Testopel

Isiphetho

I-Testosterone idlala indima ebalulekile empilweni nasenhlalakahleni yabesilisa. Ukuqonda ukusetshenziswa kwayo, izinzuzo, kanye nezingozi ezingaba khona kubalulekile kunoma ubani ocabanga ukwelashwa nge-testosterone. Njalo xhumana nomhlinzeki wezempilo ukuze unqume ukuthi i-testosterone iyafaneleka yini esimweni sakho esithile.