I-Lincomycin - Ukusetshenziswa, Isilinganiso, Imiphumela Engemihle Nokunye Okuningi

Isingeniso: Kuyini i-Lincomycin?

I-Lincomycin umuthi wama-antibiotic ongowesigaba se-lincosamide. Isetshenziswa kakhulu ukwelapha izifo ezahlukahlukene zamagciwane, ikakhulukazi lezo ezibangelwa amagciwane angenawo umoya kanye nezinto ezithile eziphilayo ezine-gram-positive. I-Lincomycin iyasebenza ekulweni nezifo esikhumbeni, endleleni yokuphefumula, kanye nezicubu ezithambile, okwenza kube inketho ebalulekile emkhakheni wezokwelapha. Itholakala kokubili ngezindlela zomlomo kanye nezokujova, okuvumela ukuguquguquka ekwelashweni ngokusekelwe ebunzimeni bokutheleleka.

Ukusetshenziswa kwe-Lincomycin

I-Lincomycin ivunyelwe ukusetshenziswa kwezokwelapha eziningana, okuhlanganisa:

• Amagciwane Esikhumba: Isebenza kahle ezimweni ezifana ne-cellulitis kanye namathumba abangelwa amagciwane asengozini.
• Ukutheleleka Ngepheshana Lokuphefumula: Isetshenziselwa ukwelapha i-pneumonia nezinye izifo emaphashini.
• Ukutheleleka Kwamathambo Namalunga: Kuyasiza ekwelapheni i-osteomyelitis kanye ne-septic arthritis.
• Ukutheleleka Kwezicubu Ezithambile: Isebenza kahle ekuthelelekeni kwemisipha kanye nezicubu ezixhumeneyo.
• Ukutheleleka Kwamazinyo: Ngezinye izikhathi kunikezwa amathumba amazinyo kanye nezinye izifo zomlomo.

Indlela Esebenza

I-Lincomycin isebenza ngokuvimbela ukwakheka kwamaprotheni ebhaktheriya. Kalula nje, ivimbela amabhaktheriya ekwenzeni amaprotheni adinga ukukhula nokwanda. Ngokuvimba ama-ribosome, okuyimishini yamaseli ebangela ukukhiqizwa kwamaprotheni, i-Lincomycin ivimbela ngempumelelo amabhaktheriya ekukhuleni, ivumela amasosha omzimba ukuba aqede ukutheleleka.

Isilinganiso nokuphathwa

Umthamo we-Lincomycin uyahlukahluka kuye ngohlobo kanye nobukhali bokutheleleka:

• Abantu abadala: Umthamo ojwayelekile womlomo ungama-500 mg njalo emahoreni ayi-6 kuya kwayi-8. Uma ungenwa yizifo ezinzima, umthamo ungandiswa ube yi-1,000 mg njalo emahoreni ayi-8.
• Izingane: Ezinganeni, umthamo uvame ukusekelwe esisindweni somzimba, ngokuvamile u-10 kuya ku-20 mg/kg/ngosuku uhlukaniswe ngemithamo emithathu.

I-Lincomycin inganikezwa ngomlomo ngesimo se-capsule noma ngomjovo ezimweni ezinzima kakhulu. Kubalulekile ukulandela imiyalelo yomhlinzeki wezempilo mayelana nomthamo kanye nokuphathwa.

Imiphumela Engemihle ye-Lincomycin

Imiphumela emibi evamile ingafaka:

• I-nausea
• Ukuvota
• Uhudo
• Ubuhlungu besisu

Imiphumela emibi kakhulu ingenzeka, njenge:

• Ukusabela okunamandla kwe-allergic: ukuqubuka, ukulunywa, ukuvuvukala
• Uhudo oluhlobene neClostridium difficile: ukutheleleka okukhulu kwamathumbu
• Izinkinga zesibindi: kuboniswa yi-jaundice noma umchamo omnyama

Iziguli kufanele zibike noma yiziphi izimpawu ezingajwayelekile noma ezinzima kumhlinzeki wazo wezempilo ngokushesha.

Ukusebenzisana kwezidakamizwa

I-Lincomycin ingasebenzisana nemithi eminingana, okuhlanganisa:

• Ama-Neuromuscular Blockers: I-Lincomycin ingathuthukisa imiphumela yale mithi, okuholela ekuphumuleni kwemisipha okwandisiwe.
• Amanye ama-antibiotics: Ukusebenzisa i-Lincomycin kanye nama-antibiotic athile kunganciphisa ukusebenza kwawo.
• Ama-anticoagulants: Kungase kube nengozi eyengeziwe yokopha uma kuthathwa ngemithi yokunciphisa igazi.

Ngaso sonke isikhathi wazisa umhlinzeki wakho wezempilo mayelana nayo yonke imithi nezithako zokudla ozithathayo ukuze ugweme ukusebenzisana okungenzeka.

Izinzuzo ze-Lincomycin

I-Lincomycin inezinzuzo eziningana zezokwelapha:

• Isebenza Kahle Ema-bacteria Amelana Namagciwane: Kuvame ukusetshenziswa lapho amanye ama-antibiotic ehluleka ngenxa yokumelana nemithi.
• Ukungena Okuhle Kwezicubu: I-Lincomycin ifinyelela ngempumelelo ezicutshini ezinegciwane, okwenza ifanelekele izifo ezijulile.
• Okunye Okungenziwa Yiziguli Ezingezwani Nomzimba: Kungaba inketho enhle ezigulini ezine-allergy ku-penicillin.

Ukuphikisana kwe-Lincomycin

Abantu abathile kufanele bagweme i-Lincomycin, okuhlanganisa:

• Abesifazane Abakhulelwe: Ngokuvamile akukhuthazwa ngesikhathi sokukhulelwa ngaphandle uma kudingeka ngempela.
• Iziguli Ezinesifo Sesibindi: Labo abanokukhubazeka kwesibindi bangase babe nobunzima bokusebenzisa umuthi.
• Umlando we-Colitis: Iziguli ezinomlando wezinkinga zesisu, ikakhulukazi i-colitis, kufanele ziyigweme ngenxa yengozi yohudo olukhulu.

Ukuqapha Nezexwayiso

Ngaphambi kokuqala i-Lincomycin, iziguli kufanele zicabangele okulandelayo:

• Umlando Wokungezwani Nomzimba: Yazisa udokotela wakho uma unomlando wokungezwani komzimba nama-antibiotic.
• Ukuhlolwa Kokusebenza Kwesibindi: Kungadingeka ukuqapha njalo labo abanezinkinga zesibindi.
• Ingozi ye-Clostridium Difficile: Qaphela izimpawu zokutheleleka kwe-C. difficile, ikakhulukazi uma unesifo sohudo esibi kakhulu.

Imibuzo Evame Ukubuzwa

• I-Lincomycin isetshenziselwani? I-Lincomycin isetshenziselwa ukwelapha izifo ezahlukahlukene zamagciwane, okuhlanganisa izifo zesikhumba, zokuphefumula, kanye nezicubu ezithambile.
• Ngingayithatha kanjani i-Lincomycin? Ingathathwa ngomlomo ngesimo se-capsule noma inikezwe ngomjovo, njengoba kuyalelwe umhlinzeki wakho wezempilo.
• Yimiphi imiphumela emibi evamile? Imiphumela emibi evamile ihlanganisa isicanucanu, ukuhlanza, isifo sohudo, nobuhlungu besisu.
• Ngingayithatha yini i-Lincomycin uma ngikhulelwe? Ngokuvamile akukhuthazwa ngesikhathi sokukhulelwa ngaphandle uma kudingeka. Xhumana nodokotela wakho.
• Yini okufanele ngiyenze uma ngiphuthelwa umthamo? Thatha umthamo ogejiwe ngokushesha nje lapho ukhumbula, kodwa weqe uma sekusondele isikhathi somthamo olandelayo. Ungaphindi.
• Ingabe i-Lincomycin iphephile ezinganeni? Yebo, kodwa umthamo uzolungiswa ngokusekelwe esisindweni sengane. Njalo landela iseluleko sikadokotela wezingane zakho.
• Ingabe i-Lincomycin ingabangela ukusabela kwe-allergy? Yebo, abanye abantu bangase babe nokusabela kokungezwani komzimba. Funa usizo lwezokwelapha uma ubona ukuqubuka noma ukuvuvukala.
• Isebenza kanjani i-Lincomycin? Ivimbela ukwakheka kwamaprotheni ebhaktheriya, ivimbele amagciwane ukuthi akhule futhi azalane.
• Ingabe kukhona ukusebenzisana kwezidakamizwa? Yebo, i-Lincomycin ingasebenzisana nama-neuromuscular blockers kanye nama-antibiotic athile. Yazisa udokotela wakho ngayo yonke imithi oyithathayo.
• Yini okufanele ngiyenze uma ngiba nesifo sohudo esibi kakhulu? Xhumana nomhlinzeki wakho wezempilo ngokushesha, njengoba kungase kubonise isimo esibucayi njengokutheleleka kwe-C. difficile.

Amagama Omkhiqizo

I-Lincomycin itholakala ngaphansi kwamagama emikhiqizo eminingana, okuhlanganisa:

• I-Lincocin
• I-Lincosamide
• I-Lincomycin Hydrochloride

Isiphetho

I-Lincomycin iyi-antibiotic enamandla edlala indima ebalulekile ekwelapheni izifo ezahlukahlukene zamagciwane, ikakhulukazi lapho amanye ama-antibiotic engasebenzi kahle. Ukuqonda ukusetshenziswa kwayo, imiphumela emibi, kanye nezinyathelo zokuqapha kungasiza iziguli ukuthi zisebenzise lo muthi ngokuphepha nangokuphumelelayo. Njalo xhumana nomhlinzeki wezempilo ukuze uthole iseluleko esiqondene nawe kanye nezinketho zokwelapha.