Soft Tissue Sarcoma

Soft Tissue Sarcoma

Treatment

  • Surgery is the mainstay of treatment of soft tissue sarcomas. Surgery generally involves wide local excision, i.e., removing cancer and some healthy tissue surrounding it. This is done to remove microscopic tumour deposits in the normal tissue.
    In case of very large tumours affecting the arms and legs, radiation and chemotherapy may be considered to shrink the tumour to avoid amputation.
  • Radiation therapy involves treating cancer with high-powered beams of energy.
    • It can be either administered before, during or after surgery.
    • Before surgery: Radiation before surgery can help shrink the tumour so that it's easier to remove.
    • During surgery: Intraoperative radiation (Brachytherapy) allows a higher dose of radiation to be delivered directly to the target area while sparing surrounding tissues.
    • Brachytherapy is used as a treatment in soft tissue sarcomas, which helps to reduce the duration of treatment and local site complications.
    • After Surgery: Postoperative radiation can help kill any remaining cancer cells and is indicated in all high-grade tumours and tumours larger than 5 cms.
  • Chemotherapy is a drug treatment that uses chemicals to kill cancer cells. Some forms of soft tissue sarcoma respond better to chemotherapy than do others.
  • Targeted therapy This may be used in selective patients.
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