• Age: Retinoblastoma is diagnosed most commonly in children below the age of 3 years. Congenital retinoblastomas are usually found during the first year of life, while other retinoblastomas tend to be diagnosed between 1- 3 years of age.
• Hereditary - The risk of retinoblastoma is much higher in children with a parent who had the congenital (heritable) form of retinoblastoma. This form mostly occurs as tumours in both the eyes (bilateral retinoblastoma).
• Insufficient consumption of fruits and vegetables by expecting mothers.
• Exposure to chemicals in gasoline or diesel exhaust during pregnancy
• When the father of the child has been exposed to radiation