Paediatrics Hodgkin's Lymphoma

Diagnosis

  • PET CT assesses whether it spread to regional nodes or distant metastases to other parts of the body. It provides functional and morphological details by utilising radiation derived from Isotope labelled Glucose molecules to detect cellular glucose uptake in cancer.
    • Lymph node biopsy - During an image-guided CT scan or a thoracoscopy, mediastinoscopy, or laparoscopy. They may remove the lymph nodes.
    • Bone marrow aspiration and biopsy - The removal of bone marrow and a small piece of bone by inserting a hollow needle into the hipbone or breastbone.
    • Blood Test - Complete blood count (CBC) and Liver and Renal function tests.
    • Pathology - The tissue and marrow samples collected are sent for further evaluation such as Histopathological examination (HPE), cytology and Immunohistochemistry (IHC), to determine the type of disease and its grading.
    • Immunohistochemistry - A laboratory test that uses antibodies to identify cancer cells based on the types of antigens or markers on the surface of the cells. This test helps diagnose specific types of lymphoma.
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