Mediastinal Tumor

Mediastinal Tumors

Treatment

  • Surgical resection- The most appropriate surgical approach for resection of a mediastinal mass depends upon the patient, the location and size of the lesion, the presumptive diagnosis, and the preference and experience of the surgeon performing the resection. Options for surgical resection include minimally invasive approaches include:
    • VATS through the chest or via subxiphoid approach, robot-assisted, trans-cervical resection)
    • Traditional open approaches (thoracotomy, median sternotomy, thoraco-sternotomy [clamshell], hemi-thoracosternotomy [hemi-clamshell] incisions).
  • VATS plays a major role in mediastinal tumors. It is a safe procedure. It can be done with either one to three keyhole incisions. The patient can be discharged after one day's stay. An advanced VATS is done when we excise larger tumors with vascular resections and reconstructions.
  • RATS has a cutting edge over conventional VATS, where the surgery is done in areas that are otherwise inaccessible owing to increased precision.
  • HITOC Hyperthermic Intrathoracic Chemotherapy is a local intraoperative perfusion of the thoracic cavity with chemotherapeutic agents after surgical cyto-reduction of malignant tumors. It is particularly carried out as an additive procedure in malignant pleural mesothelioma, Thymoma with pleural spread, and secondary pleural carcinomatosis in select patients.
  • Use of high-powered energy beams from sources of X-rays and protons to kill cancer cells. The machine moves around, directing radiation to precise points on the body.
    It is often used in combination with chemotherapy or when surgery is not an option.
  • Stereotactic Body Radiotherapy (SBRT) - It is a form of radiation therapy used in very early-stage cancer. SBRT is an intense radiation treatment that is very useful in the case of moving tumors. The patient can breathe normally while being treated as the robot follows the motion of the tumor and treats it.
  • High precision techniques like Intensity Modulated Radiotherapy (IMRT), Image guided Radiotherapy (IGRT), and Volumetric Modulated Arc therapy (VMAT/Rapid Arc) are useful in targeting the tumor accurately and avoiding normal tissue injury.
  • Chemotherapy- This depends on the histopathology of the mediastinal tumor.
  • Targeted therapy- This depends on the histopathology of the mediastinal tumor.
  • Immunotherapy- This depends on the histopathology of the mediastinal tumor.
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