• Sex- Men are at a higher risk
• Age- More common in people over the age of 60
• Smoking increases the risk of Ileal cancer
• Alcohol consumption increases the risk of Ileal cancer
• Diets high in red meat and salted or smoked foods increase the risk of Ileal cancer
• Inherited syndromes - People with certain inherited conditions like
• Familial Adenomatous Polyposis (FAP)
• Peutz-Jeghers syndrome (PJS)
• Hereditary NonpolyPosis Colon Cancer (HNPCC)
• Autoimmune Conditions - Autoimmune inflammatory bowel diseases like Crohn’s Disease and Celiac sprue increase the risk of small bowel cancers
• Immunosuppression- People who are immunosuppressed (post-organ transplant or in conditions like HIV) are at a higher risk of developing Ileal cancers.