Best Ewing sarcoma Doctors in Indore

Ewing sarcoma is a rare and aggressive form of cancer that primarily affects the young population, including adolescents and young adults (10-20 years of age). The disease is characterised by a unique genetic mutation, resulting from the fusion of the EWSR1 and FLI1 genes, which leads to the formation of an abnormal EWS-FLI1 protein. This mutation is spontaneous and not inherited. However, it is most commonly found in the hip bones, ribs, or long bones like the femur (thighbone), tibia (shinbone), or humerus (upper arm bone).

At Apollo Hospitals in Indore, a dedicated team of specialists and doctors, highly skilled in treating Ewing sarcoma, come together to provide expert care for this condition. In the following sections, we will explore the various types/stages of Ewing sarcoma.

Types/Stages of Ewing Sarcoma

Ewing sarcoma lacks distinct stages or types but can be broadly categorised based on its location into two primary types:

• Osseous Ewing sarcoma: Originating within the bones, this form commonly affects the pelvis, ribs, or long bones such as the femur or tibia.

• Extraosseous Ewing sarcoma: Beginning in the soft tissues surrounding the bones, such as the muscles, tendons, or nerves, this variant can occur in various locations, including the chest wall, trunk, or extremities.

Symptoms of Ewing Sarcoma

Here are some key symptoms that may suggest the onset of Ewing sarcoma:

• Pain or swelling in the affected area

• Unexplained fever

• Persistent fatigue

• Unintentional weight loss

• Nerve compression leads to numbness, tingling, or paralysis in the affected area

Tests to Diagnose Ewing Sarcoma

At Apollo Hospitals in Indore, the best doctors specialising in Ewing sarcoma treatment utilise various tests to diagnose the condition, including:

• Imaging Tests: X-rays, MRIs, or CT scans provide detailed images to reveal any abnormal growths or tumours within the body.

• Biopsy: Involves the extraction of a small tissue sample from the affected area, which is then analysed under a microscope to confirm the presence of cancer cells.

• Blood Tests: These can detect markers or signs indicating the presence of cancer, such as elevated levels of certain proteins or enzymes.

• Bone Scan: A radioactive tracer is injected into the bloodstream to highlight areas of abnormal bone growth or metastasis, aiding in the detection and staging of cancer.

• PET Scan: This evaluates tissue metabolic activity, detecting areas of heightened glucose uptake, indicative of cancer presence or disease spread.

Treatment or Surgery Options for Ewing Sarcoma at Apollo Hospitals, Indore

At Apollo Hospitals in Indore, a team of skilled doctors specialising in Ewing sarcoma treatment offers diverse treatment options for Ewing sarcoma, providing personalised and comprehensive care:

• Chemotherapy: Drugs are used to destroy rapidly dividing cancer cells.

• Radiation Therapy: High-energy radiation is used to annihilate cancer cells.

• Surgery: The tumour and affected bone or tissue are surgically removed.

• Targeted Therapy: This involves using drugs that target specific genetic mutations in cancer cells, such as the EWS-FLI1 fusion protein.

• High-dose chemotherapy with stem cell support: This involves using high-dose chemotherapy followed by the infusion of stem cells to replenish the bone marrow.

• CAR T-cell therapy: An investigational treatment for recurrent Ewing sarcoma, employs genetically engineered T cells to precisely target and eliminate cancer cells.

  At Apollo Hospitals, we strive to provide the best doctors and specialists specialising in Ewing sarcoma treatment who are dedicated to helping our patients fight this rare disease.