Best Ewing sarcoma Doctors in Chennai

Ewing sarcoma is a rare and aggressive form of cancer that primarily affects the young population, including adolescents and young adults (10-20 years of age). It is marked by a unique genetic mutation, resulting from the fusion of EWSR1 and FLI1 genes, which leads to the formation of an abnormal EWS-FLI1 protein. The mutation is spontaneous and not inherited. The exact causes of this disease are not fully understood, but it is known that the mutation can occur anywhere in the body. However, it is most commonly found in the hip bones, ribs, or long bones like the femur (thighbone), tibia (shinbone), or humerus (upper arm bone).

At Apollo Hospitals in Chennai, a dedicated team of specialists and doctors, highly skilled in treating Ewing sarcoma, come together to provide expert care for this condition. In the following sections, we will explore the various types/stages of Ewing sarcoma.

Types/Stages of Ewing Sarcoma

Ewing sarcoma does not have distinct stages or types. However, based on its location, it could be classified into two broad categories:

• Osseous Ewing sarcoma: This type originates in bones, which is the most common form, accounting for approximately 70% of cases.

• Extraosseous Ewing sarcoma: This type begins in the soft tissues surrounding the bones, such as cartilage or muscles.

Symptoms of Ewing Sarcoma

Here are some key symptoms that may suggest the onset of Ewing sarcoma:

• Pain or swelling in the affected area

• Unexplained fever

• Persistent fatigue

• Unintentional weight loss

• Lump or mass near the affected area

• Reduced range of motion in the affected limb

Tests to Diagnose Ewing Sarcoma

At Apollo Hospitals in Chennai, the best doctors specialising in Ewing sarcoma treatment utilise various tests to diagnose the condition, including:

• Imaging tests: X-rays, MRIs, or CT scans can detect abnormal growths and provide detailed images of the affected area.

• Biopsy: A tissue sample is extracted from the affected area for detailed analysis under a microscope to confirm the presence of cancer cells.

• Blood tests: These tests can identify markers or signs that indicate the presence of cancer.

• Bone Scan: This test uses a small amount of radioactive material to highlight bone abnormalities and detect the spread of cancer to the bones.

• Molecular testing: Genetic tests on the tumour sample can identify specific mutations, such as the EWS-FLI1 fusion gene.

• PET Scan: This imaging test reveals the metabolic activity of tissues and organs, helping to identify cancerous cells.

Treatment or Surgery Options for Ewing Sarcoma at Apollo Hospitals, Chennai

At Apollo Hospitals in Chennai, a team of experienced doctors specialising in Ewing sarcoma treatment offers a range of personalised care options:

• Chemotherapy: Drugs are used to destroy rapidly dividing cancer cells throughout the body.

• Radiation Therapy: High-energy radiation is used to target and destroy cancer cells.

• Surgery: The tumour and affected bone or tissue are surgically removed.

• Targeted Therapy: This involves using drugs that target specific genetic mutations in cancer cells, such as the EWS-FLI1 fusion protein, to minimise damage to healthy cells.

• Immunotherapy: This approach boosts the body’s immune system to recognise and attack cancer cells more effectively.

• Stem cell transplant: Following high-dose chemotherapy, a stem cell transplant restores bone marrow function, which is crucial for healthy blood cell production.

  At Apollo Hospitals, we strive to provide the best doctors and specialists specialising in Ewing sarcoma treatment who are dedicated to helping our patients fight this rare disease.