Nitroprusside - Uses, Dosage, Side Effects and More

Chiyambi: Kodi Nitroprusside ndi chiyani?

Nitroprusside ndi mankhwala amphamvu ochepetsa kuthamanga kwa magazi omwe amagwiritsidwa ntchito makamaka m'malo odzidzimutsa kuti athetse kuthamanga kwa magazi (kuthamanga kwa magazi) komanso kulephera kwa mtima. Imagwira ntchito pochepetsa mitsempha yamagazi, kulola magazi kuyenda mosavuta, zomwe zimathandiza kuchepetsa kuthamanga kwa magazi ndikuchepetsa ntchito pamtima. Nitroprusside nthawi zambiri imaperekedwa kudzera m'mitsempha kuchipatala chifukwa imagwira ntchito mwachangu komanso chifukwa chofuna kuyang'aniridwa mosamala.

Ntchito za Nitroprusside

Nitroprusside yavomerezedwa kuti igwiritsidwe ntchito m'njira zosiyanasiyana zachipatala, kuphatikizapo:

• Mavuto Othamanga Kwambiri: Kawirikawiri imagwiritsidwa ntchito pazochitika zoopsa pomwe kuthamanga kwa magazi kumafunika kuchepetsedwa mwachangu kuti tipewe mavuto monga sitiroko kapena matenda a mtima.
• Kulephera kwa Mtima: Nitroprusside ingathandize kuthana ndi zizindikiro za kulephera kwa mtima mwa kuchepetsa ntchito ya mtima komanso kukonza kuyenda kwa magazi.
• Kuthamanga kwa magazi kolamulidwa: Pa opaleshoni ina, ingagwiritsidwe ntchito kuyambitsa kuthamanga kwa magazi kolamulidwa, zomwe zimathandiza kuti pakhale matenda abwino ochitidwa opaleshoni.

Mmene Ntchito

Nitroprusside imagwira ntchito potulutsa nitric oxide, molekyulu yomwe imamasula minofu yosalala m'makoma a mitsempha yamagazi. Kupumula kumeneku kumapangitsa kuti mitsempha yamagazi ikule, zomwe zimachepetsa kukana kwa mitsempha yamagazi ndikuchepetsa kuthamanga kwa magazi. Mwachidule, zimathandiza mitsempha yamagazi kutseguka, zomwe zimapangitsa kuti magazi azitha kuyenda mosavuta kudzera mwa iyo.

Mlingo ndi Utsogoleri

Nitroprusside imaperekedwa kudzera m'mitsempha, ndipo mlingo umasiyana malinga ndi momwe wodwalayo alili komanso momwe wodwalayo amayankhira chithandizo.

Mlingo Woyenera wa Akuluakulu:

Mlingo woyambira ndi 0.3 mpaka 0.5 ma microgram pa kilogalamu imodzi pamphindi imodzi, zomwe zingasinthidwe kutengera momwe magazi amayendera. Mlingo waukulu sayenera kupitirira ma microgram 10 pa kilogalamu imodzi pamphindi imodzi.

Mlingo wa Ana:

Kwa ana, mlingo nthawi zambiri umawerengedwa kutengera kulemera, kuyambira pa 0.5 mpaka 3 micrograms pa kilogalamu imodzi pamphindi, ndi kuyang'aniridwa mosamala.

Ulamuliro:

Nitroprusside imaperekedwa kudzera mu IV line, ndipo kuyang'anira kuthamanga kwa magazi nthawi zonse ndikofunikira kuti tipewe kutsika kwa kuthamanga kwa magazi mwachangu.

Zotsatirapo za Nitroprusside

Zotsatira zoyipa za Nitroprusside zitha kukhala izi:

• mutu
• chizungulire
• nseru
• Flushing
• Palpitations

Zotsatira zoyipa zingaphatikizepo:

• Hypotension yayikulu: kuthamanga kwa magazi kotsika kwambiri
• Cyanide toxicity: makamaka pogwiritsa ntchito nthawi yayitali
• Methemoglobinemia: vuto lomwe hemoglobin silingathe kunyamula mpweya bwino

Kuyanjana kwa Mankhwala

Nitroprusside imatha kuyanjana ndi mankhwala angapo, kuphatikizapo:

• Mankhwala ena a antihypertensive: Kugwiritsa ntchito Nitroprusside pamodzi ndi mankhwala ena ochepetsa kuthamanga kwa magazi kungayambitse kutsika kwa magazi kwambiri.
• Sildenafil (Viagra): Izi zitha kuwonjezera zotsatira zochepetsa kuthamanga kwa magazi, zomwe zingayambitse mavuto ena.
• Okodzetsa: Zingawonjezere chiopsezo cha kuthamanga kwa magazi ngati zigwiritsidwa ntchito pamodzi.

Ubwino wa Nitroprusside

Ubwino wa Nitroprusside ndi monga:

• Kuyamba Kwachangu: Imagwira ntchito mwachangu, zomwe zimapangitsa kuti ikhale yoyenera pazochitika zadzidzidzi.
• Mlingo Wosinthika: Mlingo wa kuthira m'thupi ungasinthidwe mosavuta kuti ukwaniritse kuthamanga kwa magazi komwe mukufuna.
• Yogwira Ntchito M'milandu Yoopsa: Ndiwothandiza kwambiri pochiza matenda oopsa kwambiri komanso kulephera kwa mtima pamene njira zina zothandizira sizingathandize.

Zotsutsana za Nitroprusside

Anthu ena ayenera kupewa Nitroprusside, kuphatikizapo:

• Azimayi Oyembekezera: Zingawononge mwana wosabadwayo.
• Odwala Chiwindi: Kulephera kugwira ntchito kwa chiwindi kungawonjezere chiopsezo cha poizoni.
• Anthu omwe ali ndi hypersensitivity: Anthu omwe ali ndi vuto la Nitroprusside kapena chilichonse mwa zigawo zake sayenera kugwiritsa ntchito.

Kusamala ndi machenjezo

Musanagwiritse ntchito Nitroprusside, odwala ayenera kudziwa izi:

• Kuwunikira: Kuwunika kuthamanga kwa magazi nthawi zonse n'kofunika kwambiri panthawi ya chithandizo.
• Kuopsa kwa Cyanide: Kugwiritsa ntchito nthawi yayitali kungayambitse kuchuluka kwa cyanide, makamaka kwa odwala omwe ali ndi vuto la impso.
• Mayeso a Labu: Kuyezetsa magazi nthawi zonse kungakhale kofunikira kuti muwone ngati pali zotsatirapo zoyipa.

Ibibazo

• Kodi Nitroprusside imagwiritsidwa ntchito pa chiyani? Nitroprusside imagwiritsidwa ntchito pochiza kuthamanga kwa magazi kwambiri komanso kulephera kwa mtima, makamaka pazochitika zadzidzidzi.
• Kodi Nitroprusside imaperekedwa bwanji? Imaperekedwa kudzera m'mitsempha kuchipatala, zomwe zimathandiza kuti munthu achitepo kanthu mwachangu komanso kuti aziyang'aniridwa mosamala.
• Zotsatira zoyipa zomwe zimachitika nthawi zambiri ndi zotani? Zotsatirapo zoyipa zomwe zimachitika nthawi zambiri zimaphatikizapo mutu, chizungulire, komanso nseru.
• Kodi Nitroprusside ingayambitse zotsatirapo zoyipa kwambiri? Inde, zingayambitse hypotension yayikulu komanso poizoni wa cyanide ngati sizikuyang'aniridwa bwino.
• Ndani ayenera kupewa Nitroprusside? Azimayi oyembekezera komanso omwe ali ndi matenda a chiwindi kapena omwe ali ndi vuto la kusamvana ndi mankhwalawa ayenera kupewa.
• Kodi Nitroprusside imagwira ntchito bwanji? Imamasula mitsempha yamagazi mwa kutulutsa nitric oxide, yomwe imachepetsa kuthamanga kwa magazi.
• Kodi Nitroprusside ndi yotetezeka kwa ana? Inde, koma mlingo wake uyenera kuwerengedwa mosamala kutengera kulemera kwa mwana.
• Kodi ndingatani ndikaphonya mlingo? Nitroprusside nthawi zambiri imaperekedwa kuchipatala nthawi zonse, kotero kuphonya mlingo sikungatheke.
• Kodi ndingathe kumwa mankhwala ena ndi Nitroprusside? Mankhwala ena amatha kusokonezana ndi Nitroprusside, choncho funsani dokotala musanagwiritse ntchito mankhwala.
• Kodi Nitroprusside imatenga nthawi yayitali bwanji kuti igwire ntchito? Nitroprusside imagwira ntchito mwachangu kwambiri, nthawi zambiri mkati mwa mphindi zochepa kuchokera pamene yaperekedwa.

Mayina A Brand

Nitroprusside imapezeka m'mafakitale osiyanasiyana, kuphatikizapo:

• Nitropress
• Nipride

Kutsiliza

Nitroprusside ndi mankhwala ofunikira kwambiri pochiza matenda oopsa a mtima komanso kulephera kwa mtima, makamaka m'malo odzidzimutsa. Kuchita kwake mwachangu komanso mlingo wosinthika kumapangitsa kuti ikhale chida chofunikira kwa opereka chithandizo chamankhwala. Komabe, chifukwa cha zotsatirapo zake komanso kuyanjana kwake, ndikofunikira kugwiritsa ntchito Nitroprusside motsogozedwa ndi dokotala.