Prochlorperazine

Chiyambi: Kodi Prochlorperazine ndi chiyani?

Prochlorperazine ndi mankhwala omwe amagwiritsidwa ntchito makamaka pochiza nseru ndi kusanza kwambiri, komanso kuthana ndi zizindikiro za matenda amisala monga schizophrenia. Ndi m'gulu la mankhwala otchedwa phenothiazines, omwe amagwira ntchito posintha momwe mankhwala alili muubongo. Prochlorperazine imapezeka m'njira zosiyanasiyana, kuphatikizapo mapiritsi, ma suppositories, ndi jakisoni, zomwe zimapangitsa kuti ikhale njira yothandiza kwambiri kwa odwala omwe ali ndi zosowa zosiyanasiyana.

Kugwiritsa Ntchito Prochlorperazine

Prochlorperazine yavomerezedwa kuti igwiritsidwe ntchito m'njira zosiyanasiyana zachipatala, kuphatikizapo:

• Mseru ndi kusanza: Kawirikawiri amaperekedwa kuti achepetse nseru ndi kusanza komwe kumachitika chifukwa cha matenda osiyanasiyana, kuphatikizapo chemotherapy, opaleshoni, kapena mankhwala ena.
• Matenda a Maganizo: Prochlorperazine imagwiritsidwa ntchito pochiza zizindikiro za schizophrenia ndi matenda ena amisala, zomwe zimathandiza kuchepetsa kuona zinthu molakwika komanso kuganiza molakwika.
• Nkhawa: Sizimagwiritsidwa ntchito kawirikawiri chifukwa cha nkhawa yayikulu kwakanthawi kochepa koma sizikulimbikitsidwa nthawi zonse ndi malangizo apano.
• Vertigo: Zingakhalenso zothandiza pochiza vertigo ndi matenda ena ofanana.

Momwe Prochlorperazine Imagwirira Ntchito

Prochlorperazine imagwira ntchito potseka ma dopamine D2 receptors muubongo. Dopamine ndi neurotransmitter yomwe imagwira ntchito yofunika kwambiri pamalingaliro, khalidwe, komanso kumva nseru. Mwa kuletsa dopamine kugwira ntchito pa ma D2 receptors awa, Prochlorperazine imathandiza kuchepetsa nseru ndipo imatha kukhazikika mumaganizo mwa odwala omwe ali ndi matenda amisala. Mwachidule, imachepetsa zizindikiro za ubongo zomwe zimayambitsa nseru komanso zimathandiza kuthana ndi zizindikiro za matenda amisala.

Mlingo ndi Utsogoleri

Mlingo wa Prochlorperazine umasiyana malinga ndi vuto lomwe wodwalayo akulandira komanso zaka zake. Nazi malangizo okhazikika:

Akuluakulu:

• Pa nseru ndi kusanza: Mlingo woyambira ndi 5 mpaka 10 mg womwe umatengedwa pakamwa katatu kapena kanayi patsiku.
• Kwa matenda amisala: Mlingo woyamba ukhoza kukhala wokwera, pafupifupi 10 mg, womwe ungasinthidwe kutengera momwe mankhwalawa akuyendera.

Zachipatala:

Kwa ana azaka ziwiri kapena kuposerapo, mlingo nthawi zambiri umadalira kulemera kwa thupi, nthawi zambiri umakhala pakati pa 0.1 ndi 0.5 mg/kg patsiku, wogawidwa m'magawo angapo.

Kawirikawiri prochlorperazine sivomerezedwa kwa ana osakwana zaka ziwiri chifukwa cha chiopsezo chowonjezeka cha zotsatirapo zoyipa. Nthawi zonse tsatirani malangizo enieni a dokotala wanu potengera malangizo omwe alipo.

Prochlorperazine ikhoza kuperekedwa pakamwa ngati piritsi, ngati suppository, kapena kudzera mu jakisoni, kutengera kuopsa kwa zizindikiro ndi kuthekera kwa wodwalayo kumwa mankhwala.

Zotsatirapo za Prochlorperazine

Monga mankhwala ena onse, Prochlorperazine ingayambitse zotsatirapo zoyipa.

Zotsatira zoyipa zodziwika bwino ndi izi:

• kugona
• chizungulire
• pakamwa youma
• kusawona
• kudzimbidwa
• Kutha
• Kuthamanga kwa magazi (hypotension)

Zotsatira zoyipa zingaphatikizepo:

• Zizindikiro za extrapyramidal (monga mayendedwe osalamulirika a minofu kapena kunjenjemera kapena kuuma kwa minofu)
• Tardive dyskinesia (kusuntha kosafunikira)
• Zotsatira zoyipa kwambiri (zidzolo, kuyabwa, kutupa)
• Matenda a Neuroleptic Malignant (vuto losowa koma loopsa)

Odwala ayenera kuonana ndi othandizira awo azaumoyo ngati akumana ndi zovuta zina kapena zovuta.

Kuyanjana kwa Mankhwala

Prochlorperazine imatha kuyanjana ndi mankhwala ndi zinthu zingapo, zomwe zingawonjezere chiopsezo cha zotsatirapo zake kapena kuchepetsa mphamvu yake. Kuyanjana kwakukulu ndikuphatikizapo:

• Ma CNS Depressants ena: Mowa, benzodiazepines, ndi opioids zingapangitse munthu kugona tulo komanso kugona.
• Antidepressants: Mankhwala ena oletsa kuvutika maganizo angawonjezere chiopsezo cha serotonin syndrome akamwedwa ndi Prochlorperazine.
• Antihistamines: Kuphatikiza ndi mankhwala ena oletsa kutupa kungayambitse kutopa kwambiri komanso kuuma pakamwa.
• Mankhwala Otalikitsa Nthawi ya QT: Kuphatikiza ndi mankhwala omwe amakhudza kugunda kwa mtima (monga maantibayotiki ena kapena mankhwala oletsa kupweteka kwa mtima) kungapangitse chiopsezo cha kutalikitsa nthawi ya QT komanso mavuto akuluakulu a mtima.

Nthawi zonse dziwitsani dokotala wanu za mankhwala onse ndi zowonjezera zomwe mukumwa kuti mupewe kuyanjana ndi mankhwala ena.

Ubwino wa Prochlorperazine

Prochlorperazine imapereka zabwino zingapo zachipatala komanso zothandiza:

• Thandizo Logwira Ntchito: Ndi yothandiza kwambiri pochiza nseru ndi kusanza kwambiri, makamaka kwa odwala omwe akulandira chithandizo cha chemotherapy kapena opaleshoni.
• Utsogoleri Wosiyanasiyana: Imapezeka m'njira zosiyanasiyana; ikhoza kukonzedwa kuti igwirizane ndi zosowa za wodwala aliyense payekha, kaya ikufunika kumwa, jakisoni, kapena kuperekedwa kudzera m'matumbo.
• Kuyamba Kwachangu: Mankhwalawa nthawi zambiri amapereka mpumulo mwamsanga ku zizindikiro, zomwe zimapangitsa kuti akhale njira yabwino kwambiri m'malo ovuta.

Zotsutsana za Prochlorperazine

Anthu ena ayenera kupewa kugwiritsa ntchito Prochlorperazine, kuphatikizapo:

• Azimayi Oyembekezera: Zingayambitse mavuto kwa mwana wosabadwayo, makamaka mu trimester yoyamba.
• Odwala Chiwindi: Anthu omwe ali ndi vuto lalikulu la chiwindi sangagwire bwino ntchito ya mankhwalawa, zomwe zimapangitsa kuti zotsatira zake zikhale zovuta kwambiri.
• Anthu Omwe Ali ndi Matenda Enaake: Odwala omwe ali ndi mbiri ya ziwengo ku phenothiazines kapena omwe ali ndi mitundu ina ya glaucoma ayenera kupewa mankhwalawa.
• Odwala omwe ali ndi Pheochromocytoma: Matendawa amakhudza zotupa zomwe zimatha kukulirakulira ndi mankhwala a phenothiazine monga Prochlorperazine.
• Anthu omwe ali ndi vuto la kutsekeka kwa mafupa: Anthu omwe ali ndi maselo ochepa m'magazi ayenera kupewa izi chifukwa cha zoopsa zomwe zingawachitikire.

Kusamala ndi machenjezo

Odwala asanayambe kugwiritsa ntchito Prochlorperazine, ayenera kukambirana mbiri yawo yachipatala ndi dokotala wawo. Zofunikira zodzitetezera ndi izi:

• Kuyang'anira Nthawi Zonse: Odwala omwe amalandira chithandizo cha nthawi yayitali angafunike kuyang'aniridwa pafupipafupi kuti awone zotsatirapo zake, makamaka zizindikiro za extrapyramidal.
• Mayeso a Labu: Kuyezetsa magazi kungakhale kofunikira kuti muwone momwe chiwindi chikugwira ntchito komanso thanzi lonse panthawi ya chithandizo.
• Kupewa Mowa: Odwala ayenera kupewa kumwa mowa akamamwa Prochlorperazine chifukwa cha chiopsezo chowonjezeka cha kugona.

Ibibazo

• Kodi Prochlorperazine imagwiritsidwa ntchito pa chiyani? Prochlorperazine imagwiritsidwa ntchito pochiza nseru ndi kusanza kwambiri, kuthetsa matenda amisala, komanso nthawi zina nkhawa.
• Kodi ndiyenera kumwa Prochlorperazine bwanji? Ikhoza kumwedwa pakamwa, ngati suppository, kapena jakisoni, kutengera momwe mulili komanso upangiri wa dokotala.
• Zotsatira zoyipa zomwe zimachitika nthawi zambiri ndi zotani? Zotsatira zodziwika bwino zimaphatikizapo kugona, chizungulire, pakamwa pouma, komanso kusawona bwino.
• Kodi ndingathe kumwa mowa ndikumwa Prochlorperazine? Ayi, mowa uyenera kupewedwa chifukwa ungawonjezere kutopa ndi zotsatirapo zina.
• Kodi Prochlorperazine ndi yotetezeka panthawi ya mimba? Kawirikawiri prochlorperazine sivomerezedwa panthawi ya mimba.
• Kodi ndingatani ndikaphonya mlingo? Imwani mlingo womwe mwaphonya mwamsanga mukangokumbukira koma musaugwiritse ntchito ngati nthawi yanu yotsatira yayandikira. Musawonjezere kawiri.
• Kodi Prochlorperazine ingayambitse zizindikiro zosiya kumwa mankhwala? Inde, kusiya mwadzidzidzi mutagwiritsa ntchito kwa nthawi yayitali sikungayambitse zizindikiro zosiya kumwa monga nseru kapena kusokonezeka maganizo. Nthawi zonse funsani dokotala wanu kuti akuthandizeni kuchepetsa thupi.
• Kodi Prochlorperazine imagwira ntchito kwa nthawi yayitali bwanji? Kawirikawiri imayamba kugwira ntchito mkati mwa mphindi 30 mpaka 60 ikamwedwa pakamwa.
• Kodi ana angatenge Prochlorperazine? Inde, koma mlingo wake uyenera kusinthidwa mosamala kutengera kulemera ndi momwe mwanayo alili.
• Ndichite chiyani ngati ndikukumana ndi zotsatira zoyipa kwambiri? Lumikizanani ndi dokotala wanu nthawi yomweyo ngati mukukumana ndi zotsatirapo zoyipa monga kunjenjemera kapena ziwengo.

Mayina A Brand

Prochlorperazine imagulitsidwa pansi pa mayina angapo a makampani, kuphatikizapo:

• Phatikizani
• Stemetil
• Procomp
• Compro (ya mawonekedwe a suppository)

Kutsiliza

Prochlorperazine ndi mankhwala ofunika kwambiri pochiza nseru ndi kusanza kwambiri, komanso kuchiza matenda amisala. Kugwira ntchito kwake bwino, kugwiritsidwa ntchito kwake mosiyanasiyana, komanso kuyamba kwake mwachangu kumapangitsa kuti ikhale chisankho chabwino kwambiri m'malo osiyanasiyana azachipatala. Komabe, ndikofunikira kugwiritsa ntchito mankhwalawa motsogozedwa ndi dokotala, poganizira zotsatirapo zake komanso momwe angagwirizanire ndi mankhwala ena. Nthawi zonse funsani dokotala wanu musanayambe kapena kusiya kumwa mankhwala aliwonse.