Digoxin - Uses, Dosage, Side Effects and More

Chiyambi: Kodi Digoxin ndi chiyani?

Digoxin ndi mankhwala ochokera ku masamba a chomera cha foxglove (Digitalis lanata). Amagwiritsidwa ntchito makamaka pochiza matenda ena a mtima, makamaka kulephera kwa mtima ndi atrial fibrillation. Mwa kukulitsa mphamvu ya mtima komanso mphamvu ya kupindika, digoxin imathandiza kuthana ndi zizindikiro ndikukweza moyo wa odwala omwe ali ndi matendawa.

Ntchito za Digoxin

Digoxin yavomerezedwa kuti igwiritsidwe ntchito m'njira zosiyanasiyana zachipatala, kuphatikizapo:

• Kulephera kwa Mtima: Ikhoza kuperekedwa kwa odwala omwe ali ndi vuto la mtima, makamaka omwe ali ndi kachigawo kochepa kotulutsa magazi, kuti achepetse zizindikiro.
• Matenda a Atrial Fibrillation: Digoxin imagwiritsidwa ntchito poletsa kugunda kwa mtima mwa odwala omwe ali ndi vuto la atrial fibrillation, vuto lomwe limadziwika ndi kugunda kwa mtima kosakhazikika.
• Atrial Flutter: Mofanana ndi atrial fibrillation, digoxin ingathandize kuchepetsa kugunda kwa mtima mwa odwala omwe ali ndi atrial flutter.

Mmene Ntchito

Digoxin imagwira ntchito poletsa enzyme yotchedwa Na+/K+ ATPase, zomwe zimapangitsa kuti calcium yambiri m'maselo a mtima iwonjezeke. Kuwonjezeka kumeneku kumawonjezera mphamvu ya kupsinjika kwa mtima (zabwino za inotropic) ndikuchepetsa kugunda kwa mtima makamaka powonjezera kamvekedwe ka vagal ndikuchepetsa kayendedwe ka atrioventricular. Mwachidule, digoxin imathandiza mtima kupopa mwamphamvu komanso moyenera komanso kuwongolera kamvekedwe kake.

Mlingo ndi Utsogoleri

Mlingo wa digoxin umasiyana malinga ndi vuto lomwe wodwalayo akulandira, zaka zake, kulemera kwake, komanso momwe impso zake zimagwirira ntchito.

Mlingo Woyenera wa Akuluakulu:

• Pa vuto la mtima: Mlingo woyamba nthawi zambiri umakhala 0.5 mpaka 0.75 mg, kenako mlingo wokonza umakhala 0.125 mpaka 0.5 mg patsiku.
• Pa matenda a atrial fibrillation: Mlingo woyambirira ukhoza kukhala wofanana, ndipo mlingo wosamalira umasinthidwa kutengera momwe wodwalayo akumvera komanso momwe wodwalayo akulekerera.

Mlingo wa Ana:

Mlingo wa ana umaperekedwa payekhapayekha ndipo umadalira kulemera kwawo, nthawi zambiri umawerengedwa ngati 10-15 mcg/kg pa mlingo woyamba, kenako ndi mlingo wosamalira.

Digoxin ikhoza kuperekedwa pakamwa mu piritsi kapena mu mawonekedwe amadzimadzi kapena kudzera m'mitsempha kuchipatala.

Zotsatirapo za Digoxin

Zotsatira zoyipa za digoxin ndi izi:

• Mseru ndi kusanza
• kutsekula
• chizungulire
• kutopa
• Kusokonezeka kwa maso (monga, kusawona bwino, mawonekedwe achikasu ndi obiriwira)

Zotsatira zoyipa zingaphatikizepo:

• Kusokonezeka kwa kayimbidwe ka mtima (arrhythmias)
• Kwambiri thupi lawo siligwirizana
• Kusalinganika kwa ma electrolyte (makamaka kuchuluka kwa potaziyamu m'thupi)

Kuyanjana kwa Mankhwala

Digoxin imatha kuyanjana ndi mankhwala ndi zinthu zingapo, kuphatikizapo:

• Okodzetsa: Zingayambitse kuchepa kwa potaziyamu m'thupi, zomwe zimawonjezera chiopsezo cha poizoni wa digoxin.
• mankhwala: Maantibayotiki ena amatha kukhudza kuchuluka kwa digoxin m'thupi.
• Maantacid: Zingasokoneze kuyamwa kwa digoxin.
• Zoletsa za Calcium Channel Zosakhala za Dihydropyridine: Zingawonjezere mphamvu ya digoxin, zomwe zimapangitsa kuti pakhale chiopsezo chowonjezeka cha zotsatirapo zoyipa.

Ubwino wa Digoxin

Ubwino wa digoxin m'zachipatala ndi monga:

• Kugwira ntchito bwino kwa mtima ndi zizindikiro zake kwa odwala omwe ali ndi vuto la mtima.
• Kuwongolera bwino kugunda kwa mtima kwa odwala omwe ali ndi vuto la atrial fibrillation.
• Kugona m'chipatala kungachepe chifukwa cha mavuto okhudzana ndi mtima.

Zotsutsana za Digoxin

Anthu ena ayenera kupewa digoxin, kuphatikizapo:

• Odwala omwe amadziwika kuti ali ndi hypersensitivity ku digoxin kapena ma digitalis glycosides ena.
• Anthu omwe ali ndi mitundu ina ya kutsekeka kwa mtima kapena bradycardia yayikulu.

Digoxin ingagwiritsidwe ntchito panthawi ya mimba ngati yasonyezedwa kuchipatala, motsogozedwa mosamala.

Kusamala ndi machenjezo

Asanayambe kugwiritsa ntchito digoxin, odwala ayenera kuyesedwa labu kuti aone momwe impso zikugwira ntchito komanso kuchuluka kwa ma electrolyte. Kuwunika pafupipafupi ndikofunikira kuti apewe poizoni. Odwala ayenera kudziwitsa dokotala wawo za mankhwala onse omwe akumwa komanso matenda aliwonse omwe alipo.

Ibibazo

• Kodi ndiyenera kuchita chiyani ngati ndaphonya mlingo wa digoxin? Imwani nthawi yomweyo mukangokumbukira, koma musagwiritse ntchito ngati nthawi yanu yotsatira yayandikira. Musawonjezere kawiri.
• Kodi ndingathe kumwa digoxin ndi chakudya? Inde, digoxin ingatengedwe ndi chakudya kapena ayi, koma kusinthasintha kwake ndikofunikira kwambiri.
• Kodi digoxin imagwira ntchito kwa nthawi yayitali bwanji? Mungayambe kumva bwino patatha masiku ochepa, koma zingatenge nthawi kuti zotsatira zake zonse zitheke.
• Kodi digoxin ndi yotetezeka kwa odwala okalamba? Inde, koma angafunike kuchepetsa mlingo ndi kuyang'aniridwa mosamala chifukwa cha kuchuluka kwa mphamvu ya mankhwalawa.
• Ndiyenera kuchita chiyani ndikakumana ndi zotsatira zoyipa? Lumikizanani ndi dokotala wanu nthawi yomweyo, makamaka ngati muli ndi zizindikiro zoopsa.
• Kodi ndingasiye kumwa digoxin mwadzidzidzi? Ayi, musasiye kumwa digoxin popanda kufunsa dokotala wanu, chifukwa izi zingakuike vuto lanu pachiwopsezo.
• Kodi digoxin imakhudza kugunda kwa mtima wanga? Inde, digoxin imatha kuchepetsa kugunda kwa mtima wanu, zomwe zimathandiza pa matenda ena a mtima.
• Kodi ndingathe kumwa mowa ndikumwa digoxin? Ndi bwino kuchepetsa kumwa mowa, chifukwa ungakhudze ntchito ya mtima komanso kusokonezana ndi mankhwala.
• Kodi ndiyenera kukaonana ndi dokotala kangati ndili ndi digoxin? Kutsatira nthawi zonse ndikofunikira, makamaka poyambira kapena kusintha mlingo wanu.
• Kodi digoxin ndi yosokoneza bongo? Ayi, digoxin siionedwa kuti ndi yoledzeretsa, koma iyenera kugwiritsidwa ntchito monga momwe yalembedwera.

Mayina A Brand

Mayina ena akuluakulu a digoxin ndi awa:

• Lanoxin
• Digitek
• Kadixin

Kutsiliza

Digoxin imagwira ntchito yofunika kwambiri pothana ndi kulephera kwa mtima ndi matenda a mtima, zomwe zimathandiza kukonza magwiridwe antchito a mtima komanso moyo wabwino wa wodwala. Ngakhale kuti ndi yothandiza, imafunika kuyang'aniridwa mosamala chifukwa cha zotsatirapo zake komanso momwe zinthu zingagwirizanire. Nthawi zonse funsani dokotala wanu kuti akupatseni upangiri ndi njira zina zothandizira.