I-Zolpidem - Ukusetyenziswa, Idosi, Iziphumo Ezingalindelekanga kunye nokunye

Intshayelelo: Yintoni iZolpidem?

I-Zolpidem liyeza elinikwa ngugqirha elisetyenziselwa unyango lwexesha elifutshane lokungalali, ingakumbi kubantu abanengxaki yokulala okanye ukuhlala belele. Likwiqela lamayeza abizwa ngokuba yi-non-benzodiazepine sedative-hypnotics kwaye yaziwa ngokuqala kwayo ngokukhawuleza ukusebenza. I-Zolpidem idla ngokuthengiswa phantsi kwamagama eempawu ezifana ne-Ambien?, Stilnox?, kunye ne-Zolfresh?, kwaye ifumaneka kwiifomyula ezikhutshwa ngoko nangoko, ezikhutshwa ixesha elide, kunye nezisetyenziswa ngolwimi oluncinci.

Ukusetyenziswa kweZolpidem

I-Zolpidem imiselwe ngokukodwa:

• Unyango lwexesha elifutshane lokungalali
• Ubunzima bokulala (ukungalali kakuhle-ukungakwazi ukulala)
• Ubunzima bokulala (ukungalali kakuhle) - kunye neefom zokukhulula ixesha elide

Ayivunywanga ukusetyenziswa ixesha elide okanye ukunyanga ixhala okanye ezinye iimeko zengqondo.

Isebenza njani iZolpidem?

I-Zolpidem iphakamisa umsebenzi we-gamma-aminobutyric acid (GABA), i-neurotransmitter kwingqondo ekhuthaza ukuphumla nokulala. Isebenza ngokukhetha kwi-GABAA receptors, inceda:

• Khuthaza ukulala ngokukhawuleza
• Ukuphucula umgangatho wokulala
• Nciphisa ukuvuka ebusuku

Ngokungafaniyo ne-benzodiazepines yendabuko, i-zolpidem inomngcipheko ophantsi wokuxhomekeka kunye nemiphumo encinci ye-muscle yokuphumla okanye i-anticonvulsant xa isetyenziswe njengoko iyalelwe.

Isisombululo kunye noLawulo

Iipilisi Ezikhutshwa Ngoko nangoko (umz., Ambien?)

• Abantu abadala: Abafazi 5 mg; amadoda 5-10 mg ngexesha lokulala
• Abantu abadala okanye abakhubazekileyo besibindi: 5 mg ngexesha lokulala
• Ukuqala kwesenzo: ~15?30 imizuzu
• Ubude bexesha: ~iiyure ezi-6?8

Iipilisi Ezikhutshwa Ngokwandiswa (umz., i-Ambien CR?)

• Abantu abadala: Abafazi 6.25 mg; amadoda 6.25-12.5 mg ngexesha lokulala
• Ibonelela ngokulala okuzinzileyo ubusuku bonke

Iipilisi ezisetyenziswa ngolwimi olungaphantsi kolwimi / izitshizi zomlomo (umz., i-Edluar?, i-Intermezzo?)

Xa uvuka phakathi kobusuku (kusele iiyure ezi-4 zokulala) kodwa kunzima ukubuyela ebuthongweni. I-Intermezzo?: 1.75?3.5 mg yedosi ephantsi engaphantsi kolwimi. Yithathe kanye ngaphambi kokulala kwaye uqinisekise ukuba ulala iiyure ezi-7?8 ukuze uphephe ukozela ngosuku olulandelayo.

Iziphumo ezisecaleni zeZolpidem

Iziphumo eziPhakathi

• Ukulala
• Utywala
• intloko ebuhlungu
• Umlomo omile
• Uhudo
• Ukukhathala
• Ukuphazamiseka kosuku olulandelayo (umz., ukozela, ukunciphisa ukuphaphama)

Iimiphumo eziMbi kakhulu

• Iindlela ezintsonkothileyo zokulala (umz., ukuhamba ulele, ukuqhuba ulele, ukutya)
• Iingxaki zeMemori
• Umbono okanye ukudideka
• Ukwalana (ukudumba, irhashalala, ubunzima bokuphefumla)
• Ukudakumba okanye iingcinga zokuzibulala (kunqabile)

Xela ukuziphatha okungaqhelekanga okanye ukulahleka kwememori kugqirha wakho ngokukhawuleza.

Ukusebenzisana kweziyobisi

I-Zolpidem inokunxibelelana ne:

• Izinto zokudambisa uxinezeleko lwe-CNS (umz., utywala, ii-opioid, ii-antipsychotics, ii-antihistamines)? ukuthomalalisa ubuthongo okwandisiweyo
• Amayeza okudakumba (ingakumbi ii-SSRI kunye nee-SNRI)
• Ii-antifungals kunye ne-CYP3A4 inhibitors (umz., i-ketoconazole, i-cimetidine, i-fluconazole)? zinokunyusa amanqanaba e-zolpidem
• I-Rifampin okanye i-St. John's Wort inokunciphisa ukusebenza kwayo

Gwema utywala okanye ezinye izinto zokuthoba ngelixa uthatha iZolpidem.

Iinzuzo zeZolpidem

• Ibangela ukulala ngokukhawuleza
• Ukuphucula ixesha lokulala ngokupheleleyo
• Inciphisa ukuvuka ebusuku
• Ifumaneka kwiindlela ezininzi (ithebhulethi, ukhupho olwandisiweyo, ulwimi olungaphantsi)
• Iziphumo ezisezantsi ezishiyekileyo xa zithathwa njengoko kuchaziwe

Ukungqinelana

Gwema iZolpidem kwizigulane ezine:

• Imbali yokuziphatha okuntsokothileyo kokulala (umzekelo, ukulala, ukuqhuba ulala)
• Ukukhubazeka okukhulu kwesibindi
• I-hypersensitivity eyaziwayo kwiZolpidem
• I-apnea yokulala okanye iingxaki ezinzulu zokuphefumla

Izilumkiso kunye nezilumkiso

• Ayijoliswanga ekusetyenzisweni ixesha elide (iiveki ezingaphezu kwezine ukuya kwezintlanu)
• Umngcipheko wokuxhomekeka kunye nokuhoxiswa ngokusetyenziswa ixesha elide
• Sebenzisa isilumkiso kwizigulane ezikhulileyo ngenxa yomngcipheko wokuwa
• Kuphephe ukukhulelwa okanye ukuncancisa ngaphandle kokuba uyalelwe ngugqirha
• Musa ukuqhuba okanye ukusebenzisa oomatshini ngosuku olulandelayo ukuba uziva uyozela

Ukunciphisa idosi yokungasebenzi kakuhle kwesibindi ngokwenqaku le-Child-Pugh.

FAQs

Isebenza ngokukhawuleza kangakanani iZolpidem?

Kwimizuzu eli-15?30 emva kokuthatha idosi.

Ndingayithatha iZolpidem qho ebusuku?

Yenzelwe ukusetyenziswa ixesha elifutshane. Ukusetyenziswa ixesha elide kunokukhokelela ekuxhomekekeni okanye ekunyamezeleni.

Kuthekani ukuba ndivuka ezinzulwini zobusuku?

Sebenzisa i-Intermezzo? (idosi ephantsi ye-sublingual zolpidem) ukuba uyalelwe. Musa ukuthatha idosi yesibini eqhelekileyo.

Ndingasela utywala ngeZolpidem?

Hayi. Utywala bunyusa umngcipheko wokuthomalalisa kunye nokuziphatha okuyingozi.

Ngaba iZolpidem ipilisi yokulala?

Ewe, sisincedisi sokulala esimiselweyo esisetyenziselwa ukunyanga ukuphuthelwa.

Ngaba iZolpidem iyakhobokisa?

Kukho umngcipheko wokwakheka komkhwa, ngakumbi ngokusetyenziswa kwexesha elide.

Ngaba iZolpidem inokubangela ukulahleka kwenkumbulo?

Ewe, i-anterograde amnesia inokwenzeka, ingakumbi ukuba awulali ubusuku bonke okanye wenza imisebenzi enzima emva kokuyithatha.

Ngaba ikhuselekile kubantu abadala?

Sebenzisa ngononophelo; iidosi ezisezantsi ziyacetyiswa ukunciphisa umngcipheko wokuwa kunye nokudideka.

Ngaba iZolpidem ingasetyenziselwa ukuxhalaba?

Hayi, ayivunywanga ukuxhalaba. Ijolise ngokukodwa ekuphuthelweni.

Ndingakwazi ukusika ithebhulethi phakathi?

Kuphela ukuba ugqirha wakho uyala. Musa ukwahlula iipilisi zokukhululwa okwandisiweyo.

Amagama eBrand

I-Zolpidem ithengiswa phantsi kweempawu ezahlukeneyo kunye namagama aqhelekileyo:

• Ambien? / Ambien CR? (e-USA)
• Stilnox? (Kwilizwe liphela)
• I-Zolfresh?, iHypnite?, iZolpidem Tartrate (iimpawu eziqhelekileyo)
• Edluar?, Intermezzo? (Iipilisi zesiNgesi)

isiphelo

I-Zolpidem sisisombululo esisebenzayo kakhulu sexesha elifutshane sokungalali, esinika ukuqalisa ukulala ngokukhawuleza kunye nomgangatho ongcono wokulala. Nangona kunjalo, kufuneka ithathwe ngononophelo phantsi kweliso likagqirha ngenxa yokuba kunokwenzeka ukuba umntu axhomekeke kuye kwaye aziphathe ngendlela engaqhelekanga yokulala. Hlala ulandela imiyalelo kagqirha wakho ukuze ufumane iziphumo ezilungileyo nezikhuselekileyo.