Olanzapine

Intshayelelo: Yintoni iOlanzapine?

I-Olanzapine liyeza le-antipsychotic eliqhelekileyo elisetyenziselwa ukunyanga iimeko zempilo yengqondo ezifana ne-schizophrenia kunye ne-bipolar disorder. Inceda ukulawula iimpawu ezifana nokubona izinto ezingekhoyo, iinkohliso, ukuguquguquka kweemvakalelo, kunye nokuphazamiseka. Ngokulinganisa imichiza ethile engqondweni, i-Olanzapine idlala indima ebalulekileyo ekuphuculeni umgangatho wobomi kubantu abanezi ngxaki.

Ukusetyenziswa kwe-Olanzapine

I-Olanzapine ivunyiwe kusetyenziso oluninzi lwezonyango, kubandakanya:

• I-Schizophrenia: Inceda ukunciphisa iimpawu ezifana nemibono kunye nokucinga okungalungelelananga.
• Ukuxhuzula: I-Olanzapine iyasebenza ekunyangeni i-manic okanye iziqendu ezixubeneyo ezinxulumene ne-bipolar disorder.
• Uxinzelelo: Ingasetyenziswa njengonyango olongezelelweyo kwingxaki enkulu yokudakumba xa amanye amayeza engonelanga.
• Ukuphazamiseka: I-Olanzapine ingasetyenziselwa ukulawula ukuphazamiseka kwizigulane ezine-schizophrenia okanye i-bipolar disorder.

Ingaba isebenza kanjani

I-Olanzapine isebenza ngokuchaphazela i-neurotransmitters kwingqondo, ngakumbi i-dopamine kunye ne-serotonin. Ezi khemikhali zidlala indima ebalulekileyo ekulawuleni isimo sengqondo kunye nokuqonda. Ngokuvala ii-receptors ezithile kwezi neurotransmitters, i-Olanzapine inceda ukuzinzisa isimo sengqondo kunye nokunciphisa iimpawu zengqondo, isenza kube lula ukuba abantu basebenze kubomi bemihla ngemihla.

Isisombululo kunye noLawulo

Umthamo we-Olanzapine uyahluka ngokwemeko ephathwayo kunye neminyaka yesigulana.

Abadala:

Idosi yokuqala eqhelekileyo ye-schizophrenia yi-10 mg kanye yonke imihla, enokuthi ihlengahlengiswe ngokusekelwe kwimpendulo kunye nokunyamezela. Kwi-bipolar disorder, idosi yokuqala ihlala yi-15 mg kanye yonke imihla.

Izigulana zabantwana:

Kubantwana abaneminyaka eyi-13-17 abane-schizophrenia, i-dose yokuqala idla ngo-2.5 ​​ukuya kwi-5 mg imihla ngemihla, kunye nohlengahlengiso olwenziweyo njengoko kuyimfuneko.

I-Olanzapine ifumaneka ngeendlela ezahlukeneyo, kuquka:

• Amacwecwe: Ithathwa ngomlomo, ngokuqhelekileyo kanye yonke imihla.
• Amacwecwe Okwahlula Ngomlomo: Ezi zinyibilika emlonyeni kwabo banengxaki yokuginya.
• Inaliti: Ukulawulwa nge-intramuscularly ukulawula ngokukhawuleza ukuphazamiseka.

Iziphumo ezisecaleni zeOlanzapine

Njengawo onke amayeza, i-Olanzapine inokubangela iziphumo ebezingalindelekanga. Iziphumo ebezingalindelekanga eziqhelekileyo ziquka:

• Ukulala
• Ukutyeba kwakho
• Umlomo omile
• Ukutyunjwa
• Ukwandisa ukutya

Iziphumo ezibi kakhulu zinokubandakanya:

• I-Neuroleptic Malignant Syndrome (NMS)
• I-Tardive Dyskinesia
• Iswekile ephezulu yegazi (hyperglycemia)
• Ukonyuka kwamanqanaba e-cholesterol
• Ukuxhamla

Izigulana kufuneka zixele naziphi na iimpawu ezingaqhelekanga kumboneleli wabo wezempilo ngokukhawuleza.

Ukusebenzisana kweziyobisi

I-Olanzapine inokunxibelelana namayeza amaninzi kunye nezinto, kubandakanya:

• CNS Depressants: Utywala, i-benzodiazepines, kunye ne-opioids inokuphucula ukuthotywa.
• Ukuxhatshazwa: Ii-SSRI ezithile kunye ne-SNRIs zinokunyusa umngcipheko we-serotonin syndrome.
• I-Antihypertensives: Amayeza oxinzelelo lwegazi anokuba neziphumo ezitshintshileyo xa ethathwa kunye ne-Olanzapine.

Hlala uxelela ugqirha wakho malunga nawo onke amayeza kunye nezongezelelo ozithathayo ukuphepha ukusebenzisana okunokwenzeka.

Izibonelelo zeOlanzapine

I-Olanzapine ibonelela ngeengenelo ezininzi zeklinikhi kunye nezisebenzayo:

• Ulawulo lweempawu olusebenzayo: Inciphisa kakhulu iimpawu ze-schizophrenia kunye ne-bipolar disorder.
• Umgangatho woBomi obuphuculweyo: Izigulana ezininzi zifumana ukusebenza ngcono kwentlalo kunye nobomi bemihla ngemihla.
• UKhetho oluguquguqukayo lwedosi: Ifumaneka kwiifom ezininzi, okwenza kube lula kwizigulane ukubambelela kwisicwangciso sabo sonyango.

Contraindications of Olanzapine

Abantu abathile kufuneka baphephe i-Olanzapine, kuquka:

• Abasetyhini abakhulelweyo: Inokubangela imingcipheko kumntwana ongekazalwa.
• Abantu abaneSifo Sesibindi: Ukungasebenzi kakuhle kwesibindi kunokuchaphazela i-metabolism yeziyobisi.
• Imbali yeeNgxaki zokungalungi: Abo baye bafumana ukuchasana kakhulu ne-Olanzapine okanye amayeza afanayo akufanele bawasebenzise.

Izilumkiso kunye nezilumkiso

Ngaphambi kokuqala i-Olanzapine, izigulane kufuneka zihlolwe ngokucokisekileyo, kuquka:

• Imbali yoNyango: Xoxa ngayo nayiphi na imbali yeswekile, ukuxhuzula, okanye iingxaki zentliziyo.
• Uvavanyo lwaseLab: Ukuhlolwa rhoqo kweswekile yegazi kunye namanqanaba e-cholesterol kuyacetyiswa.
• Ukujongwa kobunzima: Ngenxa yomngcipheko wokufumana ubunzima, ukuhlolwa kobunzima rhoqo kuyacetyiswa.

FAQs

• Kufuneka ndenze ntoni ukuba ndiphosa ithamo le-Olanzapine? Ukuba uphose ithamo, yithathe ngokukhawuleza xa ukhumbula. Ukuba kusondele ixesha ledosi yakho elandelayo, tsiba idosi oyiphosileyo kwaye uqalise kwakhona ishedyuli yakho yesiqhelo. Musa ukuphinda kabini.
• Ngaba ndingayeka ukuthatha i-Olanzapine ngokukhawuleza? Hayi, ukuyeka ngokukhawuleza kunokukhokelela kwiimpawu zokurhoxisa. Soloko udibana nogqirha wakho phambi kokuba wenze naluphi na utshintsho kwirejimeni yeyeza.
• Ngaba i-Olanzapine ikhuselekile ekusebenziseni ixesha elide? I-Olanzapine inokukhuseleka ekusebenziseni ixesha elide phantsi kweliso lonyango, kodwa ukubeka iliso rhoqo kwiziphumo ebezingalindelekanga kubalulekile.
• Ngaba ndingasela utywala ngelixa ndithatha i-Olanzapine? Kungcono ukuphepha utywala, njengoko kunokonyusa ukozela kunye nezinye iziphumo ebezingalindelekanga.
• Ngaba i-Olanzapine iya kubangela ubunzima? Ubunzima bobunzima bungumphumo oqhelekileyo wecala. Xoxa ngezicwangciso kunye nogqirha wakho ukulawula lo mngcipheko.
• Ngaba iOlanzapine ingasetyenziswa kubantwana? Ewe, i-Olanzapine inokumiselwa kubantwana abaneminyaka eyi-13 nangaphezulu kwiimeko ezithile, kodwa ukubekwa esweni ngononophelo kuyafuneka.
• Kufuneka ndenze ntoni xa ndifumana iziphumo ebezingalindelekanga? Qhagamshelana nomboneleli wakho wezempilo ngokukhawuleza ukuba ufumana ubunzima obukhulu okanye malunga neziphumo ebezingalindelekanga.
• Ndingawathatha amanye amayeza nge-Olanzapine? Soloko udibana nogqirha wakho phambi kokuba uthathe nawaphi na amayeza amatsha okanye izongezo ukuze ugweme ukusebenzisana.
• Ithatha ixesha elingakanani ukuba iOlanzapine isebenze? Ezinye izigulana zinokubona ukuphucuka ngaphakathi kweentsuku ezimbalwa, kodwa kunokuthatha iiveki ezininzi ukufumana izibonelelo ezipheleleyo.
• Ngaba kukho umngcipheko wokuba nesifo seswekile ngelixa use-Olanzapine? Ewe, kukho umngcipheko ophezulu weswekile yegazi kunye nesifo seswekile. Ukubeka iliso rhoqo kubalulekile.

Amagama eBrand

I-Olanzapine ithengiswa phantsi kwamagama amaninzi, kuquka:

• Zyprexa
• I-Zyprexa Zydis (iipilisi eziqhekezayo ngomlomo)
• Zyprexa Relprevv (ifomu etofwayo)

isiphelo

I-Olanzapine liyeza elibalulekileyo lokulawula i-schizophrenia kunye ne-bipolar disorder, ebonelela ngeenzuzo ezibalulekileyo kulawulo lweempawu kunye nomgangatho wobomi. Ngelixa isebenza ngokubanzi, kubalulekile ukuba uqaphele iziphumo ebezingalindelekanga, ukusebenzisana kweziyobisi, kunye nokuchasana. Ukubeka iliso rhoqo kunye nonxibelelwano oluvulekileyo kunye nababoneleli bezempilo kunokunceda ukuqinisekisa unyango olukhuselekileyo nolusebenzayo.