Nifedipine

Intshayelelo: Yintoni iNifedipine?

I-Nifedipine liyeza elisetyenziselwa ukunyanga uxinzelelo lwegazi oluphezulu (uxinzelelo lwegazi) kunye neentlobo ezithile ze-angina (intlungu yesifuba). Kukwiklasi yeziyobisi ezaziwa ngokuba zii-calcium channel blockers, ezinceda ukuphumla nokwandisa imithambo yegazi, nto leyo eyenza kube lula ukuba intliziyo impompe igazi. I-Nifedipine ifumaneka kwiifom ezahlukeneyo, kubandakanywa ukukhutshwa ngokukhawuleza kunye neepilisi zokukhululwa okwandisiweyo, okuvumela ukuguquguquka kwizicwangciso zonyango.

Ukusetyenziswa kweNifedipine

I-Nifedipine ivunyiwe kusetyenziso oluninzi lwezonyango, kubandakanya:

• Uxinzelelo lwegazi: Inceda ukunciphisa uxinzelelo lwegazi, ukunciphisa umngcipheko wokuhlaselwa yintliziyo kunye ne-stroke.
• Angina Pectoris: I-Nifedipine iyasebenza ekudambiseni iintlungu zesifuba ezibangelwa kukuhla kokuhamba kwegazi entliziyweni.
• Isiganeko sikaRaynaud: Inokukunceda ukunciphisa iimpawu zale meko, ebangela ukunciphisa ukuhamba kwegazi kwiminwe kunye neenzwane.
• Umsebenzi Wangaphambili: Kwezinye iimeko, i-nifedipine isetyenziswa ngaphandle kweleyibhile ukunceda ukukhulula isibeleko kunye nokulibazisa ukusebenza kwangaphambi kwexesha.

Ingaba isebenza kanjani

I-Nifedipine isebenza ngokuthintela i-calcium ukuba ingangeni kwiiseli zentliziyo kunye neendonga zemithambo yegazi. I-calcium ibalulekile kwi-contraction ye-muscle, ngoko ngokuthintela ukungena kwayo, i-nifedipine ibangela ukuba izihlunu zikhululeke. Oku kuphumla kukhokelela ekwandeni kwemithambo yegazi, nto leyo ethoba uxinzelelo lwegazi kwaye icuthe umsebenzi wentliziyo. Ngamagama alula, inceda intliziyo yakho impompe ngokufanelekileyo kwaye inciphise uxinzelelo kwinkqubo yakho yentliziyo.

Isisombululo kunye noLawulo

Umthamo we-nifedipine unokwahluka ngokusekelwe kwimeko ephathwayo kunye nempendulo yesigulane. Nazi iidosi eziqhelekileyo:

Abadala:

• Uxinzelelo lwegazi: Idosi yokuqala ngokuqhelekileyo i-30 mg ye-nifedipine yokukhululwa okwandisiweyo kanye yonke imihla, enokuthi ihlengahlengiswe ngokusekelwe kwimpendulo yoxinzelelo lwegazi.
• Angina: I-dose yokuqala yesiqhelo yi-10 mg ye-nifedipine ekhutshwe ngokukhawuleza kathathu ngosuku, enokulungiswa njengoko kufuneka.

Iintsholongwane:

Umthamo wabantwana umiselwa ngumboneleli wezempilo ngokusekelwe kubunzima kunye neemfuno ezithile zempilo.

I-Nifedipine idla ngokuthathwa ngomlomo, kunye okanye ngaphandle kokutya. Iifom zokukhululwa ezongeziweyo akufuneki zicunyuzwe okanye zihlafuneke.

Iziphumo ezisecaleni zeNifedipine

Iziphumo eziqhelekileyo ziquka:

• intloko ebuhlungu
• Utywala
• Ukuqhuma
• Ukudumba emilenzeni okanye emaqatheni
• I sizathu

Iziphumo ezibi kakhulu zinokubandakanya:

• Ukukhawuleza okanye ukungahambi kakuhle kwentliziyo
• Ukwaliwa kakhulu (irhashalala, ukurhawuzelelwa, ukudumba)
• Iintlungu zesifuba
• Iingxaki zesibindi (ziboniswa yi-jaundice)

Izigulana kufuneka zifune unyango ukuba zifumana naziphi na iziphumo ebezingalindelekanga ezimandundu.

Ukusebenzisana kweziyobisi

I-Nifedipine inokunxibelelana namayeza amaninzi, kuquka:

• Izithinteli zeBeta: Ukudibanisa oku kunokunyusa umngcipheko weengxaki zentliziyo.
• Amayeza e-antifungal: Njenge ketoconazole, enokunyusa amanqanaba e-nifedipine egazini.
• amachiza: Njenge-erythromycin, enokuthi ichaphazele indlela i-nifedipine esebenza ngayo.
• Ijusi yeGrapefruit: Oku kunokunyusa inani le-nifedipine egazini, okukhokelela ekunyuseni kwemiphumo emibi.

Ngalo lonke ixesha wazisa umboneleli wakho wezempilo malunga nawo onke amayeza kunye nezongezo ozithathayo.

Iinzuzo zeNifedipine

I-Nifedipine ibonelela ngeenzuzo ezininzi zeklinikhi:

• Ulawulo olusebenzayo loxinzelelo lwegazi: Iluncedo kakhulu kwizigulane ezingaphenduli kakuhle kwamanye amayeza e-antihypertensive.
• Uncedo olukhawulezileyo lwe-Angina: I-Nifedipine inokukhulula ngokukhawuleza intlungu yesifuba, ukuphucula umgangatho wobomi kulabo abane-angina.
• Ukusetyenziswa kwezinto ezininzi: Ingasetyenziswa kwiimeko ezahlukeneyo, kubandakanya uxinzelelo lwegazi kunye ne-Raynaud's phenomenon.
• Ulwakhiwo-Ukhupho olwandisiweyo: Oku kuvumela idosi kanye ngosuku, ukuphucula ukubambelela kunyango.

Ukuchasana kweNifedipine

Abantu abathile kufuneka bakuphephe ukusebenzisa i-nifedipine, kuquka:

• Abasetyhini abakhulelweyo: Isenokungakhuseleki ngexesha lokukhulelwa.
• Izigulana ezineSifo esiMandundu sesibindi: I-Nifedipine i-metabolized esibindini, kwaye ukungasebenzi kakuhle kunokukhokelela ekunyuseni kwamanqanaba eziyobisi.
• Abo baneemeko ezithile zentliziyo: Njenge-aortic stenosis enzima okanye i-angina engazinzanga.

Soloko udibana nomboneleli wezempilo ukuze abone ukuba i-nifedipine ikulungele na.

Izilumkiso kunye nezilumkiso

Ngaphambi kokuqala i-nifedipine, izigulane kufuneka ziqwalasele oku kulandelayo:

• Ukubeka iliso rhoqo: Uxinzelelo lwegazi kufuneka lubekwe esweni rhoqo ukuqinisekisa ukuba iyeza liyasebenza.
• Iimvavanyo zokuSebenza kwesibindi: Izigulane ezinemiba yesibindi zinokufuna ukubeka iliso rhoqo.
• Kuphephe Ukuyekwa Ngesiquphe: Ukuyeka i-nifedipine ngequbuliso kunokukhokelela kuxinzelelo oluphezulu lwegazi.

Xoxa ngazo naziphi na iimeko zempilo ezikhoyo okanye iinkxalabo kunye nomboneleli wakho wezempilo ngaphambi kokuba uqale unyango.

FAQs

• Kufuneka ndenze ntoni ukuba ndiphosa ithamo le-nifedipine? Ukuba uphose ithamo, yithathe ngokukhawuleza xa ukhumbula. Ukuba kusondele ixesha ledosi yakho elandelayo, tsiba idosi oyiphosileyo kwaye uqhubeke neshedyuli yakho yesiqhelo. Musa ukuphinda kabini.
• Ngaba ndingasela utywala ngelixa ndithatha i-nifedipine? Kungcono ukunciphisa ukusetyenziswa kotywala, njengoko kunokonyusa umngcipheko weziphumo ebezingalindelekanga ezifana nesiyezi kunye noxinzelelo lwegazi olusezantsi.
• Ngaba i-nifedipine ikhuselekile ekusebenziseni ixesha elide? Ewe, xa umiselwe ngumboneleli wezempilo, i-nifedipine inokukhuseleka ekusebenziseni ixesha elide, kodwa ukubeka iliso rhoqo kubalulekile.
• Ngaba i-nifedipine inokubangela ubunzima? Ukuzuza ubunzima akusiyo impembelelo yecala eliqhelekileyo, kodwa ezinye izigulane zinokufumana ukugcinwa kwamanzi, oku kunokukhokelela ekudumbeni.
• Kufuneka ndenze ntoni xa ndifumana iziphumo ebezingalindelekanga? Qhagamshelana nomboneleli wakho wezempilo ukuba ufumana naziphi na iziphumo ebezingalindelekanga, ngakumbi ukuba zibukhali okanye zizingisa.
• Ngaba ndingathatha i-nifedipine kunye namanye amayeza oxinzelelo lwegazi? Ewe, i-nifedipine ingasetyenziswa kunye namanye amayeza e-antihypertensive, kodwa oku kufuneka kwenziwe phantsi kweliso likagqirha.
• Kuthatha ixesha elingakanani ukuba i-nifedipine isebenze? I-Nifedipine inokuqalisa ukunciphisa uxinzelelo lwegazi kwiiyure ezimbalwa, kodwa kungathatha iintsuku ezininzi ukubona umphumo opheleleyo.
• Ngaba kukhuselekile ukusebenzisa i-nifedipine ngexesha lokukhulelwa? I-Nifedipine kufuneka isetyenziswe ngexesha lokukhulelwa kuphela xa ifunwa ngokucacileyo kwaye imiselwe ngumboneleli wezempilo.
• Ngaba ndingayeka ukuthatha i-nifedipine ngokukhawuleza? Hayi, ukuyeka i-nifedipine ngequbuliso kunokubangela i-spike kuxinzelelo lwegazi. Hlala udibana nogqirha wakho ngaphambi kokuba uyeke.
• Ndingenza ntoni xa ndinokwaliwa kakhulu? Funa unyango olukhawulezileyo ukuba ufumana iimpawu zokwaliwa kakhulu, ezinjengobunzima bokuphefumla, ukudumba kobuso okanye umqala, okanye irhashalala.

Amagama eBrand

I-Nifedipine ithengiswa phantsi kwamagama amaninzi, kuquka:

• Adalat
• procardia
• Nifedical
• Afeditab

isiphelo

I-Nifedipine liyeza elixabisekileyo lokulawula uxinzelelo lwegazi kunye ne-angina, enikezela ngeenzuzo ezibalulekileyo ekuphuculeni impilo ye-cardiovascular. Ukuqonda ukusetyenziswa kwayo, iziphumo ebezingalindelekanga, kunye nonxibelelwano kubalulekile kunyango olukhuselekileyo nolusebenzayo. Soloko udibana nomboneleli wezempilo ukuze ufumane iingcebiso zomntu kwaye uqinisekise ukuba i-nifedipine lolona khetho lufanelekileyo kwiimfuno zakho zempilo.