Prochlorperazine

Nhanganyaya: Chii chinonzi Prochlorperazine?

Prochlorperazine mushonga unonyanya kushandiswa kurapa kuda kurutsa kwakanyanya uye kurutsa, pamwe nekurapa zviratidzo zvezvirwere zvepfungwa zvakaita seschizophrenia. Iri muboka remishonga inozivikanwa se phenothiazines, inoshanda nekuchinja kuenzana kwemakemikari muuropi. Prochlorperazine inowanikwa mumhando dzakasiyana-siyana, kusanganisira mapiritsi, suppositories, uye jekiseni, zvichiita kuti ive sarudzo inoshanda kune varwere vane zvinodiwa zvakasiyana.

Mashandisirwo eProchlorperazine

Prochlorperazine inotenderwa kushandiswa kwakasiyana-siyana mukurapa, kusanganisira:

• Nausea uye Kurutsa: Inowanzo shandiswa kuderedza kuda kurutsa kwakanyanya uye kurutsa kunokonzerwa nemamiriro akasiyana-siyana, kusanganisira chemotherapy, kuvhiyiwa, kana mamwe marapirwo.
• Matambudziko epfungwa: Prochlorperazine inoshandiswa kudzora zviratidzo zve schizophrenia nezvimwe zvirwere zvepfungwa, zvichibatsira kuderedza kuona zvinhu zvisipo uye kufungidzira.
• Kuzvidya mwoyo: Kashoma kushandiswa zvisina kunaka pakuzvidya mwoyo kwenguva pfupi asi hazviwanzokurudzirwa nemirairo iripo.
• Vertigo: Inogonawo kushanda pakurapa vertigo nedzimwe matambudziko ekuenzanisa.

Mashandiro anoita Prochlorperazine

Prochlorperazine inoshanda nekuvhara dopamine D2 receptors muuropi. Dopamine ineurotransmitter ine basa guru mumanzwiro, maitiro, uye kunzwa kuda kurutsa. Nekudzivisa dopamine kushanda pamareceptor aya eD2, Prochlorperazine inobatsira kuderedza kunzwa kuda kurutsa uye inogona kudzikamisa manzwiro evarwere vane matambudziko epfungwa. Nemashoko akareruka, inodzikamisa zviratidzo zveuropi zvinokonzera kuda kurutsa uye inobatsira kudzora zviratidzo zvehutano hwepfungwa.

Chipimo chemushonga uye Administration

Chipimo cheProchlorperazine chinosiyana zvichienderana nechirwere chiri kurapwa uye zera remurwere. Heano nhungamiro dzakajairika:

Vakuru:

• Kune kuda kurutsa nekurutsa: Mushonga wekutanga unowanzo shandiswa 5 kusvika 10 mg unotorwa nemuromo katatu kusvika kana kana pazuva.
• Kune zvirwere zvepfungwa: Muyero wekutanga unogona kunge wakakwira, ungangoita 10 mg, izvo zvinogona kugadziriswa zvichienderana nemhinduro.

Pediatrics:

Kune vana vane makore maviri zvichikwira, chiyero chinowanzo enderana nehuremu hwemuviri, kazhinji chinotangira pa 0.1 kusvika 0.5 mg/kg pazuva, chakakamurwa kuita madosi akawanda.

Prochlorperazine haiwanzokurudzirwa kuvana vari pasi pemakore maviri nekuda kwekuwedzera kwenjodzi dzemigumisiro yakaipa. Gara uchitevera mirairo chaiyo yachiremba wako zvichienderana nemirairo iripo.

Prochlorperazine inogona kunwiwa nemuromo muchimiro chepiritsi, semushonga wekuwedzera, kana nejekiseni, zvichienderana nekuoma kwezviratidzo uye kugona kwemurwere kutora mushonga.

Migumisiro yeProchlorperazine

Kufanana nemishonga yese, Prochlorperazine inogona kukonzera migumisiro yakaipa.

Zvakajairika mhedzisiro zvinosanganisira:

• Kukurova
• Chizutu
• Dry mouth
• Chiratidzo chakasvibiswa
• Constipation
• Sedation
• Kuderera kweropa (hypotension)

Serious side effects inogona kusanganisira:

• Zviratidzo zvekunze kwepiramidhi (zvakadai sekufamba kwetsandanyama kusingadzoreki kana kudedera kana kuomarara)
• Tardive dyskinesia (kufamba kusingatarisirwi)
• Zvakanyanya allergic reactions (mapundu, itching, kuzvimba)
• Neuroleptic malignant syndrome (chirwere chisingawanzoitiki asi chinotyisidzira hupenyu)

Varwere vanofanirwa kubata mutarisiri wavo wehutano kana vakasangana nemhedzisiro yakaoma kana inorambira.

Kubatana Kwemishonga

Prochlorperazine inogona kushanda pamwe chete nemishonga yakasiyana-siyana, izvo zvinogona kuwedzera njodzi yemigumisiro kana kuderedza kushanda kwayo. Kushanda pamwe chete kukuru kunosanganisira:

• Mamwe ma CNS Depressants: Doro, benzodiazepines, uye opioid zvinogona kuwedzera hope uye kunyaradza.
• Antidepressants: Mimwe mishonga inorwisa kuora mwoyo inogona kuwedzera njodzi yekubatwa ne serotonin syndrome kana ikatorwa neProchlorperazine.
• Antihistamines: Kusanganisa nemamwe maantihistamine kunogona kukonzera kunyaradzwa kwakanyanya uye kuoma kwemuromo.
• Mishonga Inowedzera Nguva yeQT: Kusanganisa nemishonga inokanganisa rhythm yemoyo (senge mimwe mishonga inorwisa mabhakitiriya kana mishonga inoderedza kusagadzikana kwemoyo) kunogona kuwedzera njodzi yekuwedzera QT uye matambudziko akakomba emwoyo.

Gara uchizivisa chiremba wako nezvemishonga yese nezvimwe zvinovaka muviri zvauri kutora kuti usasanganise mishonga yacho.

Mabhenefiti eProchlorperazine

Prochlorperazine ine mabhenefiti akawanda ekurapa uye anoshanda:

• Kubatsira Kunoshanda: Inoshanda zvikuru mukurapa kuda kurutsa kwakanyanya uye kurutsa, kunyanya kune varwere vari kurapwa nechemotherapy kana kuvhiyiwa.
• Multile Administration: Inowanikwa mumhando dzakasiyana-siyana; inogona kugadziriswa zvichienderana nezvinodiwa nemurwere mumwe nemumwe, kungave kuchida kupiwa nemuromo, jekiseni, kana kupihwa netsvina.
• Kurumidza kutanga: Mushonga uyu unowanzo batsira kubva kuzviratidzo nekukurumidza, zvichiita kuti uve sarudzo inokosha munzvimbo dzakakomba.

Zvinopesana neProchlorperazine

Vamwe vanhu vanofanira kudzivisa kushandisa Prochlorperazine, kusanganisira:

• Vakadzi Vakazvitakura: Zvinogona kukonzera njodzi kumwana ari mudumbu, kunyanya mumwedzi mitatu yekutanga yekuzvitakura.
• Varwere vane Chirwere cheChiropa: Avo vane chirwere chechiropa chakakomba vanogona kusakwanisa kushandisa mushonga uyu zvinobudirira, zvichiita kuti pave nemigumisiro yakawedzera.
• Vanhu Vane Mamwe Matambudziko Ehutano: Varwere vane nhoroondo yeallergies kune phenothiazines kana avo vane mamwe marudzi e glaucoma vanofanira kudzivisa mushonga uyu.
• Varwere vane Pheochromocytoma: Dambudziko iri rinosanganisira bundu rinogona kuipa kana ukashandisa phenothiazines seProchlorperazine.
• Vanhu vane Kudzvinyirirwa kweBone Morrow: Avo vane masero mashoma eropa vanofanira kudzivisa izvi nekuda kwenjodzi dzakakura.

Chenjedzo uye Nyevero

Varwere vasati vatanga Prochlorperazine, vanofanira kukurukura nhoroondo yavo yezvekurapa nevanopa rubatsiro rwehutano. Zvinokosha zvekudzivirira zvinosanganisira:

• Nguva Dzose Kuongorora: Varwere vari kurapwa kwenguva refu vangada kugara vachiongororwa kuti vaone migumisiro yemishonga iyi, kunyanya zviratidzo zvekunze kwepiramidhi.
• Lab Tests: Kuongororwa kweropa kunogona kudiwa kuti utarise mashandiro echiropa uye hutano hwese panguva yekurapwa.
• Kudzivisa Doro: Varwere vanofanira kurega doro pavanenge vachitora Prochlorperazine nekuda kwekuwedzera kwenjodzi yekuraradza.

FAQs

• Chii chinoshandiswa neProchlorperazine? Prochlorperazine inoshandiswa kurapa kuda kurutsa kwakanyanya uye kurutsa, kugadzirisa matambudziko epfungwa, uye dzimwe nguva kuzvidya mwoyo.
• Ndinofanira kutora sei Prochlorperazine? Inogona kutorwa nemuromo, semushonga wekuwedzera simba, kana kubaiwa jekiseni, zvichienderana nemamiriro ako ezvinhu uye zano rachiremba.
• Ndezvipi zvinowanzoitika? Zvinowanzoitika zvinosanganisira kurara, dzungu, muromo wakaoma, uye kusaona zvakanaka.
• Ndinganwa doro here ndichitora Prochlorperazine? Kwete, doro rinofanira kudziviswa nekuti rinogona kuwedzera kunyaradza uye zvimwe zvinokanganisa.
• Prochlorperazine yakachengeteka here panguva yekuzvitakura? Prochlorperazine haiwanzokurudzirwa panguva yekuzvitakura.
• Chii chandinofanira kuita kana ndikapotsa dose? Inwa mushonga wawakanga warasikirwa nawo nekukurumidza paunenge uchiyeuka asi usautore kana yava nguva yekuti utore mushonga unotevera. Usawedzera kaviri.
• Prochlorperazine inogona kukonzera zviratidzo zvekurega kushandisa mushonga here? Ehe, kurega kamwe kamwe mushure mekushandisa kwenguva refu hakuwanzo kukonzera zviratidzo zvekurega kushandisa zvakaita sekuda kurutsa kana kusagadzikana. Gara uchibvunza chiremba wako kuti uwane hurongwa hwakachengeteka hwekudzikisa.
• Zvinotora nguva yakareba sei kuti Prochlorperazine ishande? Kazhinji inotanga kushanda mukati memaminitsi makumi matatu kusvika makumi matanhatu kana ikatorwa nemuromo.
• Vana vanogona kutora Prochlorperazine here? Ehe, asi muyero wemushonga unofanira kugadziriswa nokungwarira zvichienderana nehuremu hwemwana nemamiriro ake ezvinhu.
• Chii chandinofanira kuita kana ndikasangana nemigumisiro yakakomba? Bata chiremba wako nekukasika kana ukasangana nematambudziko akakomba akadai sekubvunda kana kuti allergic reactions.

Mazita eBrand

Prochlorperazine inotengeswa pasi pemazita akasiyana-siyana, anosanganisira:

• Compazine
• Stemetil
• Procomp
• Compro (yefomu re suppository)

mhedziso

Prochlorperazine mushonga unobatsira pakurapa kuda kurutsa kwakanyanya uye kurutsa, pamwe nekurapa matambudziko epfungwa. Kushanda kwayo zvakanaka, kushandiswa kwakasiyana-siyana, uye kutanga kwayo nekukurumidza kunoita kuti ive sarudzo inosarudzwa munzvimbo dzakasiyana dzekurapa. Zvisinei, zvakakosha kushandisa mushonga uyu uchitungamirirwa nemupi wehutano, uchifunga nezvemigumisiro inogona kuitika uye kupindirana kwayo. Gara uchibvunza chiremba wako usati watanga kana kurega chero mushonga.