Mhinduro yakananga
Kuongororwa kweSGPT (serum glutamic pyruvic transaminase, iyo inowanzonzi ALT kana alanine aminotransferase) kunoyera enzyme inoburitswa kubva mumasero echiropa ichipinda muropa kana masero iwayo akuvara. Kukwira kweSGPT kunoratidza kutsamwa kwemasero echiropa, kwete chirwere chaicho. Kuongororwa kweSGPT kwakajairika hakubvisi chirwere chechiropa, kusanganisira cirrhosis.
Key tora kutora
- SGPT neALT bvunzo imwe chete: SGPT ndiro zita rekare remurabhoritari wekuIndia re alanine aminotransferase.
- SGPT inoratidza kukuvara kwemasero echiropa, kwete chikonzero chacho: chiropa chine mafuta, hepatitis inotapukira, doro, mishonga nezvimwe zvinovaka muviri zvinogona kukonzera izvi.
- Kuongororwa kweSGPT kwakajairika kunonyaradza asi hakuna mhinduro.: fibrosis yakakura uye cirrhosis zvinowanzo famba nema enzymes akajairwa kana kuti anenge akajairika.
- Nhamba yacho yoga hairevi zvakawanda: SGPT inodudzirwa pamwe chete neSGOT (AST), ALP, GGT, bilirubin, albumin, platelet count uye imaging.
- Mareferensi akasiyana pakati pemarabhoritari: gara uchiverenga kukosha kwako uchienzanisa nehuwandu hwakadhindwa pamushumo wako wega.
Pakuona
| chinhu | umboo |
|---|---|
| Test name | SGPT / ALT (alanine aminotransferase) |
| chiratidza zvizhinji | Ropa, rinowanzobva mutsinga yeruoko |
| Zvazvinoratidza | Kukuvara kana kubuda kwemasero echiropa (hepatocytes) |
| Kazhinji inorayirwa se | Chikamu chepanel yekuongororwa kwechiropa (LFT), chisingawanzoitiki chega |
| Kutsanya | Hazvidikanwi paSGPT pachayo; kutsanya kunogona kudiwa kune mimwe miedzo yakaunganidzwa mudhirowa imwe chete, tevera mirairo yerabhoritari yako |
| Nguva yekudhonza ropa | Maminetsi angangoita mashanu kusvika gumi, kusanganisira kunyoresa uye kumanikidzwa pamusoro penzvimbo yakaboorwa |
| Reporting | Marabhoritari mazhinji anotaura zuva rimwe chete kana zuva rinotevera; nguva inoenderana neyuniti |
| Reference range | Zvakasiyana nerabhoritari uye nzira dzacho; zvakadhindwa pamushumo wako |
Uyewo anozivikanwa se
- Kuongororwa kweALT, alanine aminotransferase
- Kuongororwa kweropa reSGPT, mazinga eSGPT
- Chikamu che "LFT", "kuyedzwa kwechiropa", "profile yechiropa"
- MuIndia, inowanzo bvunzwa se "bvunzo ye enzyme yechiropa" kana "bvunzo ye jaundice", SGPT chimwe chezvinhu zviri mumapaneru aya, kwete paneru rese.
Chii chinonzi bvunzo yeSGPT
Alanine aminotransferase ienzyme inowanikwa mukati memasero echiropa, ine huwandu hushoma mutsandanyama dzeitsvo, dzemwoyo nedzemapfupa. Iyi enzyme inobatsira kutamisa mapoka emaamino panguva yekushandiswa kwemaamino acid. Kana masero echiropa azvimba, achishushikana kana kufa, alanine aminotransferase inobuda uye huwandu hweropa hunokwira.
Nekuti enzyme iyi inoenderana nechiropa, SGPT ndeimwe yezviratidzo zvinobatsira zvekukuvara kwehepatocellular. Zvisinei, SGPT inoyera kukuvara kwete mashandiro . Basa rekugadzira chiropa rinoratidzwa zviri nani nealbumin, prothrombin time/INR uye bilirubin.
Ndiani anofanira kuongororwa uku?
- Vanhu vane zviratidzo zvinoratidza chirwere chechiropa: jaundice, weti yakasviba, tsvina yakachenuruka, kuda kurutsa kunogara kuripo, kusagadzikana kwemudumbu kurudyi, kuneta kusingatsananguriki kana kuvaviwa.
- Vanhu vari kushandisa mishonga inozivikanwa kuti inokanganisa chiropa: mushonga wekurwisa TB, methotrexate, mimwe mishonga yekurwisa pfari, mishonga yekurwisa mavhairasi, mimwe mishonga yekuuraya fungus nemishonga inorwisa mabhakitiriya. Nguva dzekutarisa dzinogadzwa neanopa mushonga wacho.
- Vanhu vanotora mishonga yeAYUSH, mishonga yemiti kana mishonga yekurovedza muviri/yekuvaka muviri: izvi ndizvo zvinozivikanwa kuti zvinokonzera kukuvara kwechiropa kunokonzerwa nemishonga muIndia.
- Vanhu vane zvinhu zvinokonzera njodzi ye metabolic: chirwere cheshuga cherudzi rwechipiri, BP yakakwira, dyslipidemia, mafuta akawandisa mumuviri. Vanhu vekuSouth Asia vanotambura nechirwere chechiropa chinoshanduka mumuviri pahuwandu hwemuviri hwakaderera kupfuura vamwe vanhu vakawanda.
- Vanhu vanozivikanwa kana kuti vanofungidzirwa kuti vane hepatitis B kana C, sechikamu chekutarisa kunosarudzwa nachiremba wehepatologist kana chiremba.
- Vanhu vanoshandisa doro nguva dzose kana kuti vanonwa doro rakawanda.
- Vanhu vane chiropa chine mafuta akawandisa panguva yekuongorora ultrasound.
Kuongororwa kweSGPT nguva dzose mumunhu akagwinya asina zvinhu zvinokonzera njodzi hakukurudzirwi nevanhu vose; kunowanzo verengerwa mumapakeji ekuongorora hutano hweIndia, uye chimwe chinhu chisina kujairika munzvimbo iyoyo chinoda tsananguro ine musoro pane kutya.
Nei bvunzo yeSGPT yaitwa
- Kuona kukuvara kwemasero echiropa kana paine zviratidzo kana zvinhu zvinoisa njodzi.
- Kubatsira kuona dambudziko rechiropa: maitiro eSGPT achipesana neALP neGGT anobatsira kupatsanura kukuvara kwehepatocellular nematambudziko echolestatic (bile flow).
- Kutarisa nekufamba kwenguva: maitiro ekudzokorora bvunzo anobatsira zvikuru pane kuverenga kamwe chete.
- Kutarisa kuchengetedzeka kwemishonga panguva yekurapwa izvo zvinogona kukanganisa chiropa.
- Kutevera mhinduro mune zvirwere zvakaita sehepatitis isingaperi kana hepatitis ye autoimmune, pamwe chete nedzimwe bvunzo.
Izvo zvisingakwanise kuonekwa kana kusaonekwa neSGPT test
Ichi ndicho chikamu chisingabatanidzwi nemishumo yakawanda, uye chinonyanya kukosha kupfuura nhamba yacho pachayo.
- SGPT haigone kukuudza chikonzero. Kurwara nehepatitis, chirwere chechiropa chinotapukira mumuviri, doro, mishonga, zvekudya zvinovaka muviri, chirwere che autoimmune hepatitis, chirwere checoeliac, chirwere chethyroid uye kukuvara kwetsandanyama zvese zvinogona kuwedzera SGPT.
- SGPT haigone kubvisa cirrhosis kana fibrosis yakakura. Ma enzymes anowanzo derera kusvika paakajairika sezvo mavanga ari kukura uye kushanda kwemasero echiropa kunorasika. Kuongororwa kweSGPT kwakajairika hakusi chiratidzo chekuti chiropa chine hutano.
- SGPT haigone kupa mhando yemafuta kana fibrosis. Haritauri chinhu nezvekuti steatosis, kuzvimba kana mavanga akawanda sei aripo. Izvi zvinoda mifananidzo, elastography, mamakisi asingakuvadzi kana dzimwe nguva biopsy.
- SGPT haigone kuona kenza yechiropa kana huwandu hwechiropa. Kansa yeropa inogona kuitika kana paine ma enzymes akajairwa. Kutora mifananidzo kunodiwa.
- SGPT haikwanise kuyera mashandiro echiropa. Chiropa chikatadza kugadzira mapuroteni kana kubvisa bilirubin chinogona kuratidza kuwedzera kwema enzymes zvishoma.
- SGPT haigone kubvisa kuvharika kwemugero we bile kana chirwere chegallstone. ALP, GGT, bilirubin uye ultrasound zvinopindura mubvunzo iwoyo.
- SGPT haisi yekurapa chiropa chete. Kukuvara kwetsandanyama dzemapfupa, kurovedza muviri kwakaoma uye mamwe matambudziko etsandanyama zvinogona kukonzera izvi pasina chirwere chechiropa.
Mhedzisiro yakataurwa seyakajairika zvinoreva kuti enzyme haina kukwidziridzwa musampuli iyoyo panguva iyoyo. Hazvirevi kuti chirwere chechiropa hachina kubuda. Kana zviratidzo zvako zvikaramba zvichienderera mberi pasinei neSGPT yakajairika, dzokera kuna chiremba wako pane kufunga kuti chiropa chako chabviswa.
Miedzo yakafanana asi yakasiyana
| bvunzo | Bvunza inopindura | Kusiyana kwazvinoita neSGPT |
|---|---|---|
| SGOT / AST | Pane kukuvara kwehepatocellular here, uye pane here maitiro ane chekuita netsandanyama kana doro? | Chiropa hachina kunyanya kuenderana neSGPT; chinowanikwawo mutsandanyama dzemwoyo nedzemapfupa. Chiyero cheAST:ALT chiri pamusoro pe2 chinoita kuti pave nekufungidzirwa kuti pane kukuvara kwechiropa kunokonzerwa nedoro; chiyero chinokwira chinogonawo kuperekedza kukura kwefibrosis. |
| Alkaline phosphatase (ALP) | Pane dambudziko rekuyerera kwenyongo kana mapfupa here? | Chiratidzo cheCholestatic pane cheHepatocellular. Chiratidzo chakakwira mumuviri wevana vari kukura uye vari nepamuviri. |
| GGT kuwedzera | ALP yakakwira inobva muchiropa here kana muti wenyongo? | Inonetsa asi haina kunyanya kutaurwa; inosanganiswa nedoro nemishonga yakasiyana-siyana. |
| Bilirubin | Sei murwere aine jaundice? | Inoyera kubata kwemavara, kwete kukuvara kwemasero. Inogona kukwira muGilbert syndrome uye muropa neSGPT yakajairika. |
| Albumin, INR/prothrombin nguva | Chiropa chinoshanda zvakanaka sei? | Zviratidzo zvebasa zvechokwadi; SGPT haisi. |
| Panera reLFT | Mufananidzo wechiropa chose | SGPT mutsetse mumwe chete mukati mepaneru iyi. SGPT imwe chete iri yoga haikwani. |
| Dumbu reUSG (sonography) | Pane mafuta here, bundu, kuzara kwemugero kana kuti matombo emunduru? | Kuongororwa kwechiropa nemafuta (ultrasound) kunoenderana nechimiro chemuviri, kwete nemakemikari. |
| Elastography (inopfupika kana kuti yakachekwa-wave) | Pane kuoma kwechiropa here kunoratidza kuti une fibrosis? | Inoongorora kuomarara, uko SGPT isingakwanise. Transient uye shear-wave elastography nzira dzakasiyana dzine miganho yakasiyana uye hadzichinjiki. |
| Kuongororwa kweHepatitis B neC | Pane hutachiona hwakati hwacho here? | Kuongororwa kwezvirwere. SGPT haigone kuona hutachiona. |
Hapana bvunzo imwe chete "yekutanga" pasi rose. Kana dambudziko riripo riri jaundice, bilirubin uye biliary ultrasound zvinowanzotungamira. Kana dambudziko riri chiropa chine mafuta ane njodzi ye metabolism, ma enzymes pamwe ne fibrosis zvinotungamira. Kana dambudziko riri kurudyi, kurwadziwa kunoratidza matombo emunduru, ultrasound zvinotungamira.
Maitiro ekugadzirira
Mirayiridzo yekugadzirira inoshanda uye yakasiyana pakati pemarabhoritari nezvipatara. Mirayiridzo yakanyorwa yerabhoritari yako ndiyo inonyanya kukosha pane chero chinhu chiri papeji rino.
- Kutsanya: SGPT haidi kutsanya kazhinji. Kutsanya kunogona kudiwa kana huwandu hwemafuta kana shuga yekutsanya yatorwa panguva imwe chete.
- Mishonga uye zvinowedzera: Uyai nerunyorwa rwakakwana, kusanganisira kushandiswa kweparacetamol, mushonga wekudzivirira TB, statins, mishonga inorwisa mabhakitiriya, mishonga inoderedza marwadzo, mishonga yeAYUSH neyemishonga, mapuroteni eupfu uye mishonga yekuwedzera yekurovedza muviri. Usamira chero mushonga wakanyorerwa kuti "uvandudze" mhedzisiro, tanga wataura neanokupa mushonga.
- Doro: Udza chiremba wako nezvekunwa kwawakaita nguva pfupi yadarika pane kuviga; kunwa kwawakaita nguva pfupi yadarika kunokanganisa kududzirwa kwemushonga.
- Kusimbisa muviri: Kudzidzira muviri zvakanyanya kana kumhanya kwenguva refu muzuva rimwe kana maviri apfuura kunogona kuwedzera SGPT neSGOT. Taura nezvazvo, uye funga nezvekudzivisa kurovedza muviri zvakanyanya usati watanga.
Kana uine chirwere cheshuga uri pakurapwa kuderedza shuga yeropa
Kana kutsanya kwakakumbirwa kuti uedze dzimwe bvunzo panguva imwe chete, bvunza chiremba anokupa mushonga kuti ungatora nguva yekutora insulin kana sulfonylureas sei, uye kuti ungatakura sei shuga inobva muropa. Kutsanya kwenguva refu usingatarisirwi pamishonga iyi kunogona kukonzera hypoglycemia.
Kana iwe uri nepamuviri
Hapana kutsanya kunodiwa paSGPT. Udza rabhoritari kuti une pamuviri, sezvo mhedzisiro yakati wandei iri muchikamu ichi ichitsanangurwa zvakasiyana panguva yekuzvitakura.
Kana uine CKD, mwoyo wako hauchakwanisi kushanda zvakanaka kana kuti une mvura shoma mumuviri wako
Usawedzera mvura inonwiwa kupfuura mwero wawakarairwa semazano akajairika ekuti "mvura inonwiwa". Tevedzera muganho wakatarwa nechikwata chako chekurapa.
Children
Kutorwa kweropa revana kunoshandisa huwandu hudiki uye huwandu hwezviratidzo zvevana. Kutsanya kwenguva refu hakuna kukodzera vana vadiki kunze kwekunge zvataurwa zvakananga nachiremba wevana.
Chii chinoitika panguva yebvunzo uye kuti zvinotora nguva yakareba sei
Chiremba wephlebotomist anochenesa ganda, oisa tourniquet uye otora ropa diki, kazhinji kubva mutsinga iri paruoko. Kudhonza pachako kunotora nguva isingasviki miniti. Kusanganisira kunyoresa, kushanya kunowanzova maminetsi mashanu kusvika gumi nemashanu. Kumanikidzwa kunobatwa panzvimbo yacho uye jira diki rinoiswa.
Mazhinji emarabhoritari anoburitsa SGPT anobuda pazuva rimwe chete kana rinotevera rekushanda, sezvo bvunzo yacho ichiitwa otomatiki. Kuchinja kwacho kwakanyatsoenderana neyuniti, nguva dzekupedzisira dzekuunganidza uye kana sampuro yacho yakatorwa panzvimbo yekuunganidza kana murabhoritari mukuru.
Kunzwisisa mushumo wako weSGPT
SGPT inoonekwa muzvikamu parita (U/L) kana zvikamu zvepasi rose parita (IU/L). Mareferensi akasiyana zvichienderana nenzira yekuyedza, rabhoritari, murume kana mukadzi uye zera, uye mamwe marabhoritari anoshandisa miganhu yepamusoro yakaderera pane mamwe. Shandisa huwandu hwakadhindwa pamushumo wako wega. Usaenzanisa kukosha kwako nehukuru kubva kune imwe rabhoritari kana webhusaiti.
Pfungwa huru dzinoshandiswa nachiremba wako:
- Kukwirira kudiki: chirwere chechiropa chinowanzo konzerwa nemafuta, doro, mishonga kana zvimwe zvinovaka muviri. Kazhinji zvinorapwa nekuongororwa kwechikonzero, kuongororwazve uye kuongororwa kwengozi ye fibrosis.
- Kukwirira kwakaratidza: zvinosimudzira mukana wekuti pave nechirwere chehepatitis chinokonzerwa nehutachiona (kusanganisira hepatitis A nehepatitis E, zvose zviri kuitika muIndia), kukuvara kwechiropa kunokonzerwa nemishonga, kukuvara kwe ischemic kana hepatitis ye autoimmune. Izvi zvinoda kuongororwa nekukurumidza kwekiriniki.
- Patani inokosha kupfuura mufananidzo mumwe chete: SGPT dominant inoratidza kukuvara kwehepatocellular; ALP neGGT dominant zvinoratidza maitiro echolestatic.
- Mafambiro acho akakosha: Kudonha kweSGPT mumurwere ari kurwara zvakanyanya hakusi mashoko akanaka.
- Low SGPT kazhinji hazvinetseki nezvehutano chete.
Nhamba dzakaita se75, 90, 110 kana 200 U/L hadzigone kuverengerwa se "dzisina kusimba" kana "dzakakomba" kana dziri dzoga. Kukosha kumwe chete uku kune zvakunoreva zvakasiyana zvikuru kumunhu ane chirwere chefivha nejaundice kwemazuva maviri, kumunhu ari kurapwa nechirwere cheTB, uye kumunhu asina zviratidzo ane chiropa chine mafuta ari pa sonography. Chiremba akakumbira bvunzo chete, ane nhoroondo yako, kuongororwa kwako nevamwe vari muboka, ndivo vanogona kuitsanangura. Mhedzisiro inosiyana zvichienderana nemamiriro ekurapa emunhu wega wega.
Chinyorwa chemazita: chainzi NAFLD chave kunzi MASLD (metabolic dysfunction-associated steatotic liver disease), NASH yava kunzi MASH , izwi rekuti steatotic liver disease , uye MetALD inotsanangura migumisiro ye metabolic nedoro panguva imwe chete (multi-society Delphi consensus, 2023). Mishumo yekare inogona kunge ichiri kushandisa mazwi apfuura.
Kana mhedzisiro yeSGPT inogona kutsausa
Zvikonzero zveSGPT yakakwidzwa zvisiri pamutemo kana zvisiri pamutemo
- Kurovedza muviri kwakaoma kana kukuvara kwetsandanyama: tsandanyama dzemapfupa dzine alanine aminotransferase; kurovedza muviri zvakanyanya, kudonha kana kubaiwa jekiseni remutsinga zvinogona kuisimudza pasina chirwere chechiropa.
- Kubviswa kweropa kwemuenzaniso panguva yekutora kana kutakurwa zvinogona kukanganisa vaongorori vakawanda.
- Kunwa doro munguva pfupi yapfuura kana chimwe chinhu chitsva chinowedzerwa zvinogona kukonzera kuwedzera kwechinguvana kunoguma kwapera kana bvunzo dzadzokororwa.
- Chirwere cheCoeliac, matambudziko ethyroid uye chirwere chetsandanyama zvinogona kukonzera kukwira kudiki kunogara kwenguva refu kusingafungidzirwe sechirwere chechiropa chikuru.
Zvinokonzera kuderera kweSGPT kwenhema kana kwenhema
- Cirrhosis yakasimbiswa: ma enzyme anowanzoita seakajairika sezvo huwandu hwehepatocyte huchidzikira, saka SGPT yakajairika inogona kugara pamwe chete nechirwere chakanyanya kukura.
- Chiropa chehepatitis B kana C chisingaperi chiri muchikamu chisina simba: ma enzymes akajairika pasinei nehutachiona huripo uye fibrosis inogona kuitika.
- Chirwere chinochinja-chinja: ma enzymes muhepatitis isingaperi neMASLD anokwira nekudzika, saka kukosha kumwe chete kwakajairika kunogona kudonha muhwindo rakanyarara.
- Kushaikwa kweVitamin B6 (pyridoxine) uye dialysis yenguva refu zvinogona kuderedza mashandiro emuviri.
- Miganho yepamusoro yekuyedza kwakasiyana: mamwe marabhoritari anoshandisa miganho yakakwira, saka kukosha kwakaratidzwa kwakajairika mune rimwe rabhoritari kunogona kuonekwa kwakakwira mune rimwe.
Njodzi nekuchengetedzeka
Kuongororwa kweropa remutsinga
Kuboorwa kweropa nguva dzose kune njodzi shoma asi chaidzo: kurwadziwa kwenguva pfupi, mavanga, kuchembera kana kufenda, uye kashoma kubuda ropa diki kana hutachiona hwemunharaunda. Vanhu vanonwa mishonga inorwisa ropa kana vane matambudziko ekubuda ropa vanogona kukuvadzwa zvakanyanya uye vanofanira kuudza chiremba wephlebotomist.
Kuongororwa kwe capillary kana kuti kutorwa kwevana
Kuongororwa kwechitsitsinho kana minwe muvacheche nevana vadiki kunokonzera kusagadzikana kwenguva pfupi uye mavanga madiki; huwandu hwesampuro hushoma, uye dzimwe nguva kudzokororwa kunodiwa kana sampuro isina kukwana kana kuti isina ropa rakabuda.
Hapana musiyano, mwaranzi kana kunyaradza kunobatanidzwa mukuongororwa kweSGPT.
Mireza tsvuku
Tsvaga rubatsiro rwekukurumidzira izvozvi
- Kuvhiringidzika, kuvhiringidzika, hope, kutaura zvisina kunaka kana maitiro asina kujairika kune munhu ane chirwere chechiropa chinozivikanwa kana chinofungidzirwa
- Kurutsa ropa, kana tsvina nhema
- Jaundice inokurumidza kudzika pamwe nekurutsa uye kutadza kuchengetedza mvura shoma
- Kunwa zvakanyanya paracetamol kana kufungidzirwa kuti ane chepfu, kunyangwe munhu wacho achinzwa zvakanaka
- Marwadzo emudumbu akanyanya pamwe nefivha uye jaundice
Ronga ongororo yezuva rimwe chete
- Jaundice itsva, weti yakasviba kana tsvina yakachenuruka
- SGPT yakakwidziridzwa zvakanyanya pamushumo, kunyanya nekuda kwekuda kurutsa, kurutsa kana kurwadziwa kwemudumbu repamusoro
- Kuzvimba kutsva mudumbu kana makumbo anoramba achikura nekukurumidza
- Ma enzymes echiropa akawedzera paunenge uri kutora mishonga yekurwisa TB, methotrexate kana mushonga uchangotanga kana chimwe chinhu chekuwedzera, taura nechiremba wako zuva rimwe chete.
- Jaundice, kuvaviwa, kurwadziwa mudumbu kana kurutsa nguva dzose panguva yekuzvitakura
Bhuka musangano wenguva dzose
- Kurerwa zvishoma kweSGPT mumunhu anonzwa zvakanaka
- Chiropa chine mafuta chakataurwa pakuongorora ultrasound uchishandisa ma enzymes akajairwa kana kuti akakwidzwa zvishoma
- Mhedzisiro yenguva refu yemuganhu inoda kuongororwazve uye kuongororwa kwengozi ye fibrosis
- Zviratidzo zvinoramba zviripo pasinei neSGPT yakajairika
Mamiriro ezvinhu anokosha
Kuberekwa
Kuchinja kudiki kunogona kuitika panguva yekuzvitakura, asi ma transaminases akakwidziridzwa haafanirwe kuonekwa sekuchinja kwakajairika kwekuzvitakura. Kuora kwemimba mudumbu, pre-eclampsia ine chiropa, HELLP syndrome, hyperemesis gravidarum uye acute viral hepatitis (kusanganisira hepatitis E, iyo inogona kuva yakanyanya panguva yekuzvitakura muIndia) zvese zvinoda kuongororwa kwekuzvitakura.
Children
Kuwanda kwevana kunosiyana nekukura kwevana vakuru. Kuwanda kwevana kunoramba kuripo kunoita kuti vafunge nezvezvirwere zve metabolic, majini, autoimmune uye tsandanyama pamwe nechirwere chechiropa chinonzi steatotic liver disease, uye zvinofanira kuongororwa nachiremba wevana kana chiremba wezvekudya zvevana.
Vakuru vakuru
Polypharmacy inoita kuti kukuvara kwechiropa kunokonzerwa nemishonga kuve nyore. Kukwira kwema enzyme kunogona kunge kushoma kunyangwe kana paine chirwere chakakomba, saka mifananidzo nezviratidzo zvebasa zvine mutoro wakawedzerwa.
Vanhu vane chirwere cheshuga
Chirwere chechiropa chinonzi Steatotic chinowanzoitika pamwe chete nechirwere cheshuga cherudzi rwechipiri, uye njodzi ye fibrosis yakanyanya. Ma enzymes haawirirane zvakanyanya ne fibrosis, saka kuongororwa kwe fibrosis kunotungamirirwa nachiremba ari kurapa kwete neSGPT chete.
Vanhu vane CKD kana vari pa dialysis
Mazinga eTransaminase anowanzova akaderera muhuwandu hwe dialysis, saka SGPT "yakajairika" haina kunyaradza zvakanyanya, uye mwero wakaderera wekuongorora kumwe unowanzo shandiswa.
Vanhu vane chirwere chemwoyo
Kuzara kwechiropa uye kubuda kweropa shoma zvinogona kuwedzera SGPT neSGOT pasina chirwere chechiropa chikuru. Mamiriro emwoyo anofanira kutariswa mukutsanangurwa.
Bvunzo reSGPT muIndia
- Terminology: Marabhoritari eIndia anotaura zvakawanda nezve SGPT uye SGOT pane ALT neAST. Miedzo yacho yakafanana; nzira yekupa mazita chete ndiyo inosiyana. Ose anowanzoonekwa paLFT printout imwe chete.
- Hepatitis A uye hepatitis E Zvichiri kukonzera chirwere chehepatitis chinokonzerwa nekuwedzera kwe transaminases muIndia, kunyanya muvanhu vechidiki, uye hepatitis E ine njodzi huru panguva yekuzvitakura.
- Kurapa kwechirwere cheTB ndiyo inowanzo kukonzera kukuvara kwechiropa kunokonzerwa nemishonga tichifunga nezvechirwere cherurindi. Kuongororwa uye chero sarudzo yemushonga ndeyachiremba ari kurapa, usamborega ATT uri wega.
- AYUSH, mishonga yemishonga uye yekurovedza muviri Zvinokonzerwa nekukuvara kwechiropa zvinozivikanwa uye hazvitaurwi zvakanyanya muIndia. Taura zvese zvaunotora, kusanganisira zvigadzirwa zvinotengeswa se "zvechisikigo" kana "kubvisa chepfu muchiropa". Kutaura kuti chigadzirwa chinorapa kana kudzora chirwere chechiropa kunotyorwawo neDrugs and Magic Remedies (Objectionable Advertisements) Act, 1954.
- Chirwere chechiropa chemuviri chiri paBMI yakaderera: Vanhu vekuSouth Asia vanowana chirwere che "steatotic liver disease" uye chirwere che "steatotic liver disease" pahuwandu hwemuviri hwakaderera uye muchiuno kupfuura vanhu vachena vekuEurope, saka chimiro "chakajairika" hachibatanidzi MASLD.
- Kushaya ropa uye anemia yekushomeka kwesimbi Zvakajairika muIndia. Izvi hazvikanganisi SGPT zvakananga asi zvinokanganisa mimwe miedzo inowanzo rairwa panguva imwe chete, yakadai seHbA1c, iyo kuvimbika kwayo kunoderera mu thalassemia trait nedzimwe hemoglobin variants.
- Dziviriro yedata: Kana ukabhuka kana kugamuchira mishumo kuburikidza newebhusaiti kana app yepamhepo, ruzivo rwako rwehutano idata rako pachako pasi peMutemo weDhijitari weDziviriro yeData reMunhu, 2023.
Mutengo neinishuwarenzi muIndia
Kuongororwa kweropa kwega kwega kweSGPT/ALT ndeimwe yeongororo dzeropa dzisingadhuri zvakanyanya dziripo muIndia, uye kazhinji kunodhura kana ukarairwa mukati meLFT pane seongororo imwe chete. Mitengo inosiyana zvakanyanya pakati pemaguta, pakati pemarabhoritari ezvipatara nenzvimbo dzekutora ropa dzega, uye pakati pemutengo wemunhu wega nepakeji. Chero nhamba yakataurwa online inoratidza chete, simbisa muripo wemari iripo zvakananga nerabhoritari usati wabhuka.
Zvinhu zvinokanganisa mutengo:
- Kana SGPT yakarairwa yoga kana mukati meLFT kana package yekuongorora hutano
- Rabhoritari iri muchipatara ichienzaniswa neketani yekuongorora yakazvimirira ichienzaniswa nenzvimbo yekuunganidzira
- Guta nenzvimbo
- Mari yekutora dzimba
- Kugadziriswa nekukurumidza kana mushure memaawa ekushanda
- Mamiriro ekubvumidzwa kwerabhoritari
- Kana bvunzo iri chikamu chehurongwa hwehurumende kana hwevashandirwi
Inishuwarenzi: bvunzo dzekuongorora varwere vasiri muchipatara kazhinji hadzifukidzwe neinishuwarenzi yehutano inotsiva kunze kwekunge yakabatana nekupinda muchipatara kana kuti inofukidzwa neOPD kana mutyairi wekuongorora hutano. Kana bvunzo yacho yaitwa panguva yekubvumidzwa muchipatara, inowanzo verengerwa muchikamu chekuferefeta. Tarisa mitemo yepolicy yako uye zvinodiwa zvekutanga zvekubvumidzwa.
Ngano nezvokwadi
| Nhema | chokwadi |
|---|---|
| Kuongororwa kweSGPT kwakajairika kunoreva kuti chiropa chine hutano. | Kurwara nechirwere chemwoyo, hepatitis B isingashande uye fibrosis inogona kuitika neSGPT yakajairika. |
| SGPT yakakwira zvinoreva kuti kukuvara kwechiropa kunogara kwenguva refu. | Zvikonzero zvakawanda, zvinosanganisira kusawirirana nemishonga, chirwere chehepatitis chinokonzerwa nehutachiona uye chirwere chechiropa chinonzi steatotic liver disease, zvinogadziriswa kana kuvandudzika kana chikonzero chacho chagadziriswa. Migumisiro inosiyana zvichienderana nemamiriro ezvinhu emunhu. |
| SGPT inokwira chete nedoro. | Doro chimwe chezvinhu zvinokonzera chirwere ichi. Chirwere chechiropa, mavhairasi, mishonga, zvekudya zvinovaka muviri, chirwere che autoimmune uye kunyange kukuvara kwetsandanyama zvinogona kukonzera izvi. |
| Chinwiwa kana muto we "kubvisa tsvina muchiropa" zvinoderedza SGPT. | Hapana mushonga wekubvisa tsvina wakaratidzwa kuti unorapa chirwere chechiropa, uye mimwe mishonga yemishonga yemishonga neyakawedzerwa mishonga yacho pachayo inokonzera kukuvara kwechiropa. Kurapa kunogadzirisa chikonzero chacho. |
| SGPT ye200 inogara ichireva chirwere chakakomba. | Kukosha kwacho kunoenderana nemufananidzo wekiriniki, mafambiro acho pamwe chete nezvimwe zvese zviri muboka. Zvinoda kuongororwa nachiremba nekukurumidza, kwete kuzvitsanangurira wega. |
| SGPT neSGOT zvakafanana. | Ma enzyme akasiyana. SGPT inoenderana nechiropa; SGOT inoratidzawo mwoyo netsandanyama. |
| Unofanira kutsanya kwemaawa gumi nemaviri kuti uongororwe chirwere cheSGPT. | SGPT pachayo haidi kutsanya. Mirayiridzo yekutsanya inowanzo enderana nedzimwe bvunzo dziri mudhirowa imwe chete uye inosiyana zvichienderana nerabhoritari. |
Mibvunzo inowanzobvunzwa
SGPT yakafanana neALT here?
Ehe. SGPT (serum glutamic pyruvic transaminase) ndiro zita rekare re alanine aminotransferase. Marabhoritari ekuIndia anowanzo dhinda SGPT, nepo mishumo yepasi rose inoshandisa ALT. Enzyme, bvunzo uye zvinoreva kliniki zvakafanana, saka hapana chikonzero chekudzokorora bvunzo kana mushumo wako ukashandisa label yakasiyana.
Zvinorevei kuti SGPT yakakwira?
SGPT yakakwira zvinoreva kuti masero echiropa ari kubuda enzyme, zvichiratidza kushatirwa kana kukuvara. Hazvitauri chikonzero chacho. Chirwere chechiropa chinonzi Steatotic, doro, mishonga, zvinovaka muviri, hepatitis yehutachiona, hepatitis ye autoimmune uye kukuvara kwetsandanyama zvese zvinogona kuitika. Chiremba wako anosanganisa kukosha kwechirwere ichi nenhoroondo yako, kuongororwa, kumwe kuongororwa kwechiropa uye dzimwe nguva mifananidzo.
Ndinofanira kutsanya ndisati ndaitwa bvunzo yeSGPT here?
Kazhinji SGPT haidi kutsanya. Kutsanya kunowanzo kumbirwa nekuti lipid profile kana shuga yekutsanya inounganidzwa panguva imwe chete. Tevedzera mirairo yakanyorwa kubva murabhoritari yako. Kana uine chirwere cheshuga pamishonga inoderedza shuga, bvunza chiremba wako kuti ungaverenga nguva yemushonga usati watsanya.
Ndichawana mhinduro yangu yeSGPT kwenguva yakareba sei?
SGPT inzira yekuongorora inoshanda yoga, uye marabhoritari mazhinji anotaura kuti yakaitwa pazuva rimwe chete kana rinotevera rekushanda. Nguva chaiyo inoenderana nechikamu chenyu chekuunganidza, kungave sampuro yacho yagadziriswa panzvimbo yacho kana kuti yaendeswa kurabhoritari huru, uye kana kugadziriswa kwekukurumidzira kwakakumbirwa.
Ko SGPT inogona here kukonzerwa nekudya uye kurovedza muviri chete?
Zvinoenderana zvachose nechikonzero chacho. Muchirwere chechiropa chine mafuta akawanda, kuchinja kwemaitiro ekudya uye kurovedza muviri kunowanzo deredza ma enzymes nekufamba kwemwedzi. Muchirwere chehepatitis chinotapukira, chirwere chehepatitis chinozviuraya kana kukuvara kunokonzerwa nemishonga, kuchinja mararamiro chete hakuna kukwana. Chero shanduko yemushonga inofanira kusarudzwa nachiremba wako.
SGPT inogona kunge yakakwira pasina zviratidzo here?
Ehe, uye izvi zvinowanzoitika. SGPT yakakwidzwa zvishoma inowanzoonekwa netsaona pachirongwa chekuongorora hutano kune munhu anonzwa zvakanaka chose. Kusavapo kwezviratidzo hakuiti kuti mhedzisiro yacho isakosha; zvinowanzoreva kuti bvunzo dzinodzokororwa, kutsvaga chikonzero uye kuongororwa kwengozi ye fibrosis zvakakodzera.
Ndeipi bvunzo inondiudza kana ndine mavanga muchiropa?
SGPT haigone kuongorora fibrosis. Kuyerwa kwekuoma kwechiropa ne elastography, non-invasive fibrosis scores uchishandisa blood parameters, uye dzimwe nguva biopsy yechiropa inoshandiswa. Transient uye shear-wave elastography inzira dzakasiyana dzine miganhu yakasiyana, uye sarudzo inoitwa nachiremba wako ari kurapa.
Sei SGPT yangu yakakwira mushure mekurovedza muviri?
Tsandanyama dzemapfupa dzine alanine aminotransferase, saka kurovedza muviri kwakasimba, kutsungirira kwenguva refu kana kukuvara kwetsandanyama zvinogona kuwedzera SGPT neSGOT pasina chirwere chechiropa. Upfu hwemapuroteni nezvimwe zvinowedzerwa usati wadzidzira zvinogonawo kubatsira. Udza chiremba wako nezvekudzidziswa kwako nezvimwe zvinowedzerwa usati waronga kumwe kuongororwa kwechiropa.
Ko SGPT inofanira kuongororwa panguva yekuzvitakura here?
SGPT inoongororwa panguva yekuzvitakura kana paine jaundice, kuvaviwa, kurwadziwa mudumbu, kurutsa nguva dzose, BP yakakwira kana pre-eclampsia inofungidzirwa. Kuwedzera kwe transaminases panguva yekuzvitakura hakurevi shanduko yakajairika mumuviri uye kunoda kuongororwa kwepamuviri, sezvo mamiriro akadai se cholestasis yekuzvitakura uye HELLP syndrome achida kurapwa nenguva.
Sources
- Rinella ME nevamwe. Chirevo cheDelphi chemasangano akawanda pamusoro pemazita matsva echirwere chechiropa chine mafuta (kusuma SLD, MASLD, MASH naMetALD), 2023.
- Nhungamiro yekiriniki yeAmerican College of Gastroenterology: kuongororwa kwemakemikari echiropa asina kujairika.
- Nhungamiro dzekiriniki dzeEuropean Association for the Study of the Liver pakukuvara kwechiropa kunokonzerwa nemishonga uye pabvunzo dzisingapindi mishonga yekuongorora kuoma kwechirwere chechiropa.
- Mapepa echokwadi eWorld Health Organisation pamusoro pehepatitis A, B, C naE.
- Zvirevo zveIndian National Association for Study of the Liver (INASL) pamusoro pekukuvara kwechiropa kunokonzerwa nemishonga uye pamusoro pechirwere chechiropa chinotapukira mumuviri/chinotapukira muvarwere vemuIndia.
- Chikamu cheCentral TB, Ministry of Health and Family Welfare, gwara rekutarisa chepfu yeropa panguva yekurapwa neTB.
- Mutemo weMishonga neMashiripiti (Zviziviso Zvinopikisa) wegore ra1954; Mutemo weDhijitari weDziviriro yeData reMunhu, wegore ra2023.
