Bicalutamide - Ngā Whakamahinga, Te Inenga, Ngā Pānga Taha me Ētahi Atu

He rongoā antiandrogen te Bicalutamide e whakamahia whānuitia ana hei rongoā i te mate pukupuku repeure mā te aukati i ngā pānga o ngā homoni tāne e whakatairanga ana i te tipu o te mate pukupuku. Kei roto i tēnei aratohu he tirohanga whānui mō ōna whakamahinga, te inenga, ngā pānga taha, ngā taunekeneke, me ngā painga.

He aha te Bicalutamide?

Ko te Bicalutamide he antiandrogen kore-steroidal e aukati ana i te mahi a ngā androgens (ngā homoni tāne) pērā i te testosterone. Mā te herea ki ngā kaiwhakawhiwhi androgen i roto i ngā pūtau matepukupuku, ka ārai i ngā androgens ki te whakaoho i te tipu o te matepukupuku prostate. He maha ngā wā ka whakamahia ngātahitia me ētahi atu maimoatanga pērā i te pokanga castration, te luteinizing hormone-releasing hormone (LHRH) analogs rānei.

Ngā Whakamahinga o te Bicalutamide

• Te Maimoatanga o te Matepukupuku Repeure: Whakamahia hei rongoā i te mate pukupuku repeure kua horapa haere, i te nuinga o te wā ka honoa ki ētahi atu rongoā homoni.
• Hauora taapiri: Ka whakamahia me ngā rongoā LHRH pēnei i te leuprolide hei aukati katoa i te androgen.
• Whakamahinga Tapanga-waho: I ētahi wā ka tohua mō ngā āhuatanga pēnei i te hirsutism (te tipu nui o te makawe) me te rongoā homoni e whakaū ana i te ira tangata i roto i ngā wāhine whakawhiti ira tangata.

Te Inenga o te Bicalutamide

Mo te mate pukupuku Prostate:

• Ngā Pakeke (Horopeta Paerewa): 50 mg ā-waha kotahi i te rā, ka tangohia i te wā kotahi i ia rā.

Mō ngā Whakamahinga i Waho i te Tapanga:

• Ka rerekē pea ngā horopeta i runga i te āhua me ngā hiahia o te tūroro. Me whai tonu i ngā taunakitanga a te kaiwhakarato hauora.

Nga Tohutohu Whakahaere:

• Ka taea te tango me te kai, me te kore rānei.
• Horomia te papa katoa ki te wai.

nui: Kaua e whakamutua te maimoatanga me te kore kōrero ki tō kaiwhakarato hauora, nā te mea ka kino ake te whanaketanga o te mate pukupuku.

Ngā Pānga Taha o te Bicalutamide

He pai te manawanui ki te Bicalutamide i te nuinga o te wā, engari ka pā pea ngā pānga taha ki ētahi tūroro.

Painga taha noa:

• He whakangungu wera
• Te uaua
• Te ngawari o te ū, te pupuhi rānei (gynecomastia)
• whakapairuaki
• Tuhinga o mua

Nga Painga Taha Tino:

• Paitanga ate: Tērā pea ka nui ake ngā whākōkī ate, ka kino rānei te ate. Ko ngā tohu ko te kōwhai o te kiri, o ngā kanohi rānei, me te mimi pouri.
• Tauhohenga mate mate: He ponana, he mākūkū, he pupuhi rānei.
• Nga take manawa: Te poto o te manawa, te mate pūkahukahu interstitial rānei (he onge).

Whakatupato:

• E taunakihia ana kia whakahaerehia he whakamātautau mahi ate i ia wā i te wā e rongoatia ana.
• Kia tūpato te whakamahi i ngā rongoā mō ngā tūroro kua pāngia e te mate ate, te mate pūkahukahu rānei.

Te taunekeneke me etahi atu rongoa

Ka taunekeneke pea a Bicalutamide me ētahi rongoā, ka pā kino pea ki te whai huatanga, ka piki ake rānei ngā pānga taha.

• Anticoagulants (hei tauira, Warfarin): Tērā pea ka whakanui ake i te pānga o te aukati toto, ka piki ake te mōrearea o te toto.
• Ngā Papanga Whākōkī CYP450: Ka ārai pea te Bicalutamide i ētahi whākōkī ate, ka pā ki te pākia o te pākia o ngā rongoā pēnei i te midazolam, i ngā statin rānei.
• Ngā Analog LHRH: He maha ngā wā e whakamahia ngātahitia ana hei aukati katoa i te androgen engari ka piki ake pea ngā pānga taha pēnei i te werawera me te ngenge.
• Ngā Rongoā Ārai-Hopu: Ka taea e ngā rongoā pēnei i te phenytoin, te carbamazepine rānei te whakaiti i ngā taumata o te Bicalutamide, ā, me whakarerekē te horopeta.
• Tāpiritanga otaota: Tērā pea ka pāngia tōna whai huatanga e ngā tāpiringa pērā i te St. John's Wort.

Ngā Hua o te Bicalutamide

• Te Ārai Homoni Whai Hua: Ka pehi katoa i te androgen ina honoa ki ngā momo LHRH.
• Kōwhiringa Kōpaki-kore: He huarahi iti ake te whakaekenga i te tango i te kākano i te pokanga mā te horomitanga ā-waha.
• Te Kounga o te Ora: Āwhina ki te whakahaere i ngā tohu o te matepukupuku repeure kua horapa haere, pērā i te mamae o te wheua me ngā raruraru mimi.
• Taupānga Whānui: He whai hua hei rongoā tahi, hei rongoā takitahi rānei, kei te āhua o te tūroro.
• Te Whakararuraru Iti ki te Oranga o Ia Rā: Nā te horomanga kotahi i te rā, me te ngāwari hoki ki te whakamahi i ngā pānga taha, he pai mō te whakamahi mō te wā roa.

Ngā Pātai Auau mō te Bicalutamide

• He aha te whakamahinga o te Bicalutamide? Ko te Bicalutamide te whakamahinga matua hei rongoā i te mate pukupuku repeure kua pāngia e te mate pukupuku repeure mā te aukati i ngā pānga o te testosterone.
• He pēhea te mahi a te Bicalutamide? Ka herea ki ngā kaiwhakawhiwhi androgen, ka ārai i ngā homoni tāne ki te whakaoho i te tipu o te mate pukupuku.
• Ka taea te whakamahi ko Bicalutamide anake? He maha ngā wā ka honoa ngātahitia me ngā rongoā LHRH, engari i ētahi wā, ka whakamahia anake mō ngā hiahia motuhake o te tūroro.
• He aha ngā pānga taha noa o te Bicalutamide? Ko ngā pānga taha noa ko te werawera, te ngenge, te mamae o te ū, me te whakapairuaki.
• He haumaru te whakamahi i te Bicalutamide mō te wā roa? Ae, engari he mea nui te aroturukitanga auau, inā koa te mahi a te ate.
• Ka pāngia te whānautanga e te Bicalutamide? Ae, tera pea ka whakaiti i te momonatanga mā te pehi i ngā taumata testosterone.
• Me pēhea te tango i te Bicalutamide? Tangohia te 50 mg o te horopeta kotahi i te rā, me te kai, me te kore kai rānei, i te wā kotahi o te rā.
• Me aha ahau ki te ngaro ahau i te horopeta? Tangohia te horopeta i ngaro i te wā tonu e mahara ana koe, ki te kore e tata ki te horopeta e whai ake nei. Kaua e tāruatia.
• Ka taea e ngā wāhine te tango i te Bicalutamide? Kāore i whakaaetia e te FDA mō te whakamahi i roto i ngā wāhine engari ka taea te tohu i waho o te tapanga mō ētahi āhuatanga.
• Ka taunekeneke a Bicalutamide me ētahi atu rongoā? Āe, ka taunekeneke pea me ngā rongoā ārai-ohorere, ngā rongoā ārai-ohorere, me ētahi tāpiringa. Me whakamōhio atu ki tō tākuta mō ngā rongoā katoa e tangohia ana e koe.

Ngā Ingoa Waitohu o Bicalutamide

• Casodex?

Opaniraa

He rongoā nui te Bicalutamide mō te rongoā i te mate pukupuku repeure kua pāngia e te mate pukupuku repeure, e whakarato ana i te aukati whai hua o te androgen me te whakapai ake i te kounga o te oranga. Ko tōna whakakotahitanga me ētahi atu rongoā he maha ngā wā ka pai ake ngā putanga maimoatanga. Mā te aroturukitanga auau me te piri ki ngā tikanga kua whakaritea ka whakarite i te haumaru me te whai huatanga.