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HomeCentres of ExcellenceDepartment of Continuous Renal Replacement Therapy (CRRT)

Department of Continuous Renal Replacement Therapy (CRRT)


CRRT (Continuous Renal Replacement Therapy) is the advanced level of external blood purification therapy (removal of waste & excess of plasma water) in patients with extensively damaged or weakened renal function over a long duration and applied for or aimed at being applied for 24 hours/day.

CRRT (Continuous Renal Replacement Therapy) is the most appropriate way of treating acute kidney injury patients who are hemodynamically very unstable & who won’t be able to understand normal dialysis.

It’s one of the most advanced technology ideal for dialysis of critically ill patients in ICU, Rhabdomyolysis (Crush injuries), ARF in the context of MSOF, Hyperkalemia, Severe Academia (pH<7.1) due to metabolic acidosis, Sepsis, SIRS, ARDS and others.

Clinical indications for CRRT are –

Renal Indications –
  • ARF with anuria
  • Azotemia
  • Fluid overload
  • Tumor lysis syndrome
  • Sepsis
  • Cerebral edema
Non-renal Indications –
  • Drug overdose
  • Metabolic disorders
  • Crush injuries
  • Sepsis
  • ARDS
  • Fluid overload
  • CHF
  • Autoimmune disorders (mTPE)

CRRT Helpline: +91-7705002277

Advantages of CRRT –

  • Hemodynamic stability – better renal recovery
  • Stable and predictable volume control
  • Stable and predictable control of chemistry
  • Stale intracranial pressure
  • Disease modification by cytokine removal

Dialysis Helpline: +91-8429029818

Role of CRRT in Acute Kidney Injury –

  • Removal of toxins (urea & creatinine)
  • Regulate electrolyte and water balance
  • Regulate acid-base balance
  • Prevent further damage to kidney tissues
  • Promote healing and renal recovery

Role of CRRT in Sepsis –

  • Removal of middle to large molecule septic mediators by convection and adsorption.
  • Removal of excess fluid and water products
  • Maintenance of acid-base balance
  • Improve cardiovascular hemodynamic – removal of cardio depressant
  • Thermoregulation

Role of CRRT in Diuretic Resistant CHF –

  • Maintain 24/7 fluid balance
    • Reduce ascites and peripheral edema
    • Relieve pulmonary edema
  • Normalize cardiac filling pressures
  • Maintain 24/7 Electrolyte and acid/base balance (CVVHD, CVVHDF)
    • Dialytic control of electrolytes
    • Delivery of bicarbonate or lactate buffer
  • Possibly prevent further renal damage or prolong renal Insufficiency
  • Possibly reduce length of stay

Role of CRRT in Acute Respiratory Distress Syndrome –

  • Maintain acid-base balance
  • Fluid control
  • Regulate electrolyte balance
  • Removal of toxins


Apollomedics Institute of Nephrology is dedicated to providing the best of healthcare services to every patient which motivated us to provide another advance level equipment CRRT (Continuous Renal Replacement Therapy) for the critically ill patients and for extensively damaged renal function patients in ICU.

We have the most advanced CRRT machine with state of the art dialysis unit and highly experienced team of doctors and technicians to take care of every situation. We have the best nephrologist in lucknow.

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