Solriamfetol: Uses, Dosage, Side Effects and More

Solriamfetol is a prescription medication primarily used to treat excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea. It is classified as a wakefulness-promoting agent and is designed to help individuals who struggle to stay awake during the day due to these conditions. Solriamfetol works by enhancing the release of certain neurotransmitters in the brain, which play a crucial role in regulating wakefulness and alertness.

Uses of Solriamfetol

Solriamfetol is approved for the following medical uses:

1. Narcolepsy: A chronic sleep disorder characterized by overwhelming daytime drowsiness and sudden attacks of sleep.
2. Obstructive Sleep Apnea (OSA): A condition where breathing repeatedly stops and starts during sleep, leading to excessive daytime sleepiness.

By addressing these conditions, Solriamfetol helps improve overall quality of life for those affected.

How It Works

In simple terms, Solriamfetol works by increasing the levels of certain chemicals in the brain that help promote wakefulness. It primarily affects the neurotransmitters dopamine and norepinephrine. By enhancing the activity of these neurotransmitters, Solriamfetol helps to improve alertness and reduce the tendency to fall asleep during the day.

Dosage and Administration

The standard dosage of Solriamfetol for adults is typically 150 mg taken once daily in the morning. Depending on individual response and tolerability, the dose may be adjusted, with a maximum recommended dose of 300 mg per day. Solriamfetol is available in tablet form and should be taken orally, with or without food. Pediatric dosing has not been established, so it is essential to consult a healthcare provider for children.

Side Effects of Solriamfetol

Common side effects of Solriamfetol may include:

• Headache
• Nausea
• Decreased appetite
• Insomnia
• Anxiety

Serious side effects, although less common, can include:

• Increased heart rate
• High blood pressure
• Mood changes, including depression or anxiety
• Allergic reactions, such as rash or swelling

Patients should report any severe or persistent side effects to their healthcare provider.

Drug Interactions

Solriamfetol may interact with several medications, including:

• Monoamine oxidase inhibitors (MAOIs)
• Other stimulants or wakefulness-promoting agents
• Certain antidepressants
• Blood pressure medications

It is crucial to inform your healthcare provider about all medications, supplements, and herbal products you are taking to avoid potential interactions.

Benefits of Solriamfetol

The clinical advantages of using Solriamfetol include:

• Improved wakefulness and alertness in individuals with narcolepsy and OSA.
• A lower risk of dependency compared to traditional stimulants.
• Flexibility in dosing, allowing for adjustments based on individual needs.
• A relatively favorable side effect profile compared to other wakefulness-promoting agents.

Contraindications of Solriamfetol

Certain individuals should avoid using Solriamfetol, including:

• Those with a known hypersensitivity to the drug or its components.
• Individuals with a history of cardiovascular issues, such as severe hypertension or arrhythmias.
• Pregnant or breastfeeding women, unless specifically advised by a healthcare provider.

Precautions and Warnings

Before starting Solriamfetol, patients should undergo a thorough evaluation, especially if they have:

• A history of heart problems or high blood pressure.
• Mental health issues, such as anxiety or depression.
• A history of substance abuse.

Regular monitoring of blood pressure and heart rate may be recommended during treatment.

FAQs

1. What is Solriamfetol used for?
   Solriamfetol is used to treat excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea.
2. How should I take Solriamfetol?
   Take Solriamfetol once daily in the morning, with or without food, as prescribed by your doctor.
3. What are the common side effects?
   Common side effects include headache, nausea, decreased appetite, insomnia, and anxiety.
4. Can I take Solriamfetol with other medications?
   Inform your doctor about all medications you are taking, as Solriamfetol can interact with certain drugs.
5. Is Solriamfetol safe during pregnancy?
   It is not recommended for use during pregnancy unless advised by a healthcare provider.
6. What should I do if I miss a dose?
   If you miss a dose, take it as soon as you remember. If it's close to the next dose, skip the missed dose and continue with your regular schedule.
7. Can I stop taking Solriamfetol suddenly?
   Consult your doctor before stopping Solriamfetol, as they may recommend a gradual reduction in dosage.
8. How long does it take for Solriamfetol to work?
   Many patients may notice improvements in wakefulness within a few days of starting treatment.
9. Are there any long-term effects of taking Solriamfetol?
   Long-term effects are still being studied, but regular monitoring by your healthcare provider is essential.
10. What should I do if I experience severe side effects?
    Contact your healthcare provider immediately if you experience severe side effects or allergic reactions.

Brand Names

Solriamfetol is marketed under the brand name Sunosi.

Conclusion

In summary, Solriamfetol is an effective medication for managing excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea. By promoting wakefulness through its action on neurotransmitters, it offers significant benefits for individuals struggling with these conditions. However, it is essential to use Solriamfetol under the guidance of a healthcare provider, considering potential side effects, drug interactions, and individual health conditions.