Memantine - Uses, Dosage, Side Effects and More

Okwu Mmalite: Gịnị bụ Memantine?

Memantine bụ ọgwụ ndenye ọgwụ nke a na-ejikarị agwọ ọrịa Alzheimer na-agafeghị oke ruo nke siri ike. Ọ bụ nke otu ọgwụ a maara dị ka NMDA antagonists nnabata. Site n'ịgbanwe ọrụ nke glutamate, neurotransmitter na-etinye aka na mmụta na ebe nchekwa, Memantine na-enyere aka melite ọrụ ọgụgụ isi ma belata ọganihu nke mgbaàmà na ndị nwere Alzheimer.

Ojiji nke Memantine

A kwadoro Memantine n'ụzọ bụ isi maka ọgwụgwọ ọrịa Alzheimer na-agafeghị oke ruo nke siri ike. Enwere ike iji ya mee ihe maka ọnọdụ ndị ọzọ, dị ka nkwarụ vaskụla na nkwarụ ọrịa Parkinson. Ọgwụ ahụ na-achọ ịkwalite ọrụ ọgụgụ isi, melite ọrụ ndụ kwa ụbọchị, na inye ndụ ndụ ka mma maka ndị ọrịa.

Olee otú Ọ na-arụ ọrụ

Memantine na-arụ ọrụ site na igbochi NMDA nnabata na ụbụrụ, nke glutamate na-arụ ọrụ. Na ọrịa Alzheimer, oke glutamate nwere ike ibute mmebi neuronal na mbelata ọgụgụ isi. Site n'ịhazi ọrụ glutamate, Memantine na-enyere aka ichebe mkpụrụ ndụ ụbụrụ site na mmebi, si otú ahụ na-eme ka ebe nchekwa na ọrụ ọgụgụ isi na ndị ọrịa dịkwuo mma.

Usoro onunu ogwu na ochichi

Ụdị usoro onunu ogwu Memantine nke okenye na-amalitekarị na 5 mg otu ugboro kwa ụbọchị. Enwere ike ịbawanye nke a ruo 10 mg kwa ụbọchị mgbe otu izu gasịrị, enwere ike ime mgbanwe ndị ọzọ dabere na nzaghachi onye ọrịa na ndidi. Oke kachasị akwadoro bụ 20 mg kwa ụbọchị, na-ekekarị ya ụzọ abụọ. Memantine dị n'ụdị mbadamba nkume yana dịka ngwọta ọnụ, na-eme ka ọ dị mfe iji nye ya.

Mmetụta Memantine

Mmetụta mmetụta Memantine na-emekarị gụnyere:

• dizziness
• isi ọwụwa
• Mgbaghoju anya
• ntachi
• ike ọgwụgwụ

Mmetụta dị egwu nwere ike ịgụnye:

• Mmeghachi omume nfụkasị ahụ (ihe ọkụ ọkụ, itching, ọzịza)
• Nnukwu dizziness ma ọ bụ nkụda mmụọ
• Iku ume ọkụ ọkụ
• ọdịdọ

Ndị ọrịa kwesịrị ịkọrọ ndị na-ahụ maka ahụike ha mmetụta ọ bụla pụrụ iche ma ọ bụ dị njọ ozugbo.

Mmekọrịta ọgwụ ọjọọ

Memantine nwere ike iji ọtụtụ ọgwụ emekọrịta ihe, gụnyere:

• Ndị ọzọ na-emegide NMDA (dịka ọmụmaatụ, ketamine)
• Ụfọdụ ọgwụ anticholinergic
• Ọgwụ ndị na-emetụta ọrụ gbasara akụrụ

Ndị ọrịa kwesịrị ịgwa onye na-ahụ maka ahụike ha gbasara ọgwụ niile ha na-aṅụ iji zere mmekọrịta ndị nwere ike.

Uru nke Memantine

Uru mbụ nke Memantine gụnyere:

• Na-ebelata ọganihu nke mgbaàmà Alzheimer
• Ịkwalite ọrụ ọgụgụ isi na ọrụ ndụ kwa ụbọchị
• Ịkwalite ogo ndụ maka ndị ọrịa na ndị nlekọta
• N'ịbụ ndị ọtụtụ ndị ọrịa na-anabata nke ọma, nwere profaịlụ mmetụta mmetụta nwere ike ijikwa

Contraindications nke Memantine

Ekwesịrị izere Memantine n'ime ndị nwere:

• Mmetụta uche a maara na Memantine ma ọ bụ ihe ọ bụla dị na ya
• Nsogbu akụrụ siri ike (mmepụta creatinine na-erughị 30 mL/min)
• Afọ ime na inye nwa ara, ọ gwụla ma uru ya karịrị ihe egwu dị na ya

Anya na ịdọ aka na ntị

Tupu ịmalite Memantine, ndị ọrịa kwesịrị ịga nyocha nke ọma, ọkachasị ma ọ bụrụ na ha nwere:

• Akụkọ gbasara ọdịdọ
• Ọrịa afọ ime
• Njide Urinary

Nleba anya mgbe niile nwere ike ịdị mkpa iji chọpụta ọrụ akụrụ na ahụike zuru oke n'oge ọgwụgwọ.

Ajụjụ

1. Kedu ihe Memantine na-eji? A na-ejikarị Memantine agwọ ọrịa Alzheimer dị oke ma dị njọ, na-enyere aka melite ọrụ ọgụgụ isi na ọrụ ndụ kwa ụbọchị.
2. Kedu ka m ga-esi were Memantine? A na-ewere Memantine ọnụ, ma ọ bụ mbadamba nkume ma ọ bụ mmiri mmiri. Soro ntuziaka dọkịta gị gbasara usoro onunu ogwu na ugboro ole.
3. Kedu ihe na-akpatakarị? Mmetụta ndị a na-ahụkarị gụnyere dizziness, isi ọwụwa, mgbagwoju anya, afọ ntachi, na ike ọgwụgwụ.
4. Enwere m ike iji ọgwụ ndị ọzọ were Memantine? Ee, ma gwa dọkịta gị gbasara ọgwụ niile ị na-aṅụ iji zere mmekọrịta ndị nwere ike ime.
5. Memantine ọ dị mma n'oge ime? A naghị atụ aro Memantine n'oge ime ime ma ọ bụrụ na uru ya karịrị ihe ize ndụ. Kpọtụrụ dọkịta gị.
6. Ogologo oge ole ka ọ na-ewe maka Memantine ịrụ ọrụ? Ụfọdụ ndị ọrịa nwere ike ịhụ mmelite n'ime izu ole na ole, mana ọ nwere ike iwe ogologo oge maka uru zuru oke iji nweta ya.
7. Enwere ike iji Memantine mee ihe maka ụdị mgbaka ndị ọzọ? Ọ bụ ezie na a na-ejikarị eme ihe maka Alzheimer, Memantine nwere ike ịdepụta aha maka ụdị dementia ndị ọzọ, dị ka nkwarụ vaskụla.
8. Kedu ihe m ga-eme ma ọ bụrụ na m na-atụ uche dose? Ọ bụrụ na ị tụfuru dose, were ya ozugbo ị chetara. Ọ bụrụ na ọ dị nso na ọgwụ na-esote, wụpụ ọgwụ agbagharala wee gaa n'ihu na nhazi oge gị.
9. Enwere mgbochi nri mgbe ị na-ewere Memantine? Enweghị ihe mgbochi nri a kapịrị ọnụ, mana idobe nri kwesịrị ekwesị ka akwadoro maka ahụike zuru oke.
10. Enwere m ike ịkwụsị ịṅụ Memantine na mberede? Akwụsịla ịṅụ Memantine na-agwaghị dọkịta gị okwu, n'ihi na nke a nwere ike ime ka mgbaàmà ka njọ.

Aha Akara

A na-ere Memantine n'okpuru ọtụtụ aha aha, gụnyere:

• M lụrụ
• Aha XR
• Ebe

mmechi

Memantine na-arụ ọrụ dị oke mkpa na njikwa ọrịa Alzheimer na-agafeghị oke na nke siri ike, na-enye ndị ọrịa na ezinụlọ ha olile anya maka ọrụ ọgụgụ isi na ịdị mma nke ndụ. Ịghọta ihe eji eme ya, uru ya na mmetụta ndị nwere ike ime nwere ike inye ndị ọrịa aka ime mkpebi ziri ezi gbasara ọgwụgwọ ha. Gakwuru onye na-ahụ maka ahụike mgbe niile maka ndụmọdụ na ntụzịaka ahaziri iche.