Bicalutamide - Uses, Dosage, Side Effects and More

Bicalutamide bụ ọgwụ antiandrogen nke a na-ejikarị agwọ ọrịa kansa prostate site na igbochi mmetụta nke homonụ nwoke nke na-akwalite uto ọrịa kansa. Nduzi a na-enye nkọwa zuru ezu banyere ojiji ya, dose ya, mmetụta ya, mmekọrịta ya na uru ya.

Kedu ihe bụ Bicalutamide?

Bicalutamide bụ ọgwụ na-anaghị egbochi steroidal nke na-egbochi ọrụ nke androgens (hormones ụmụ nwoke) dị ka testosterone. Site na ijikọ na androgen receptors na mkpụrụ ndụ kansa, ọ na-egbochi androgens ịkwalite uto nke kansa prostate. A na-ejikarị ya eme ihe na ọgwụgwọ ndị ọzọ dị ka ịwa ahụ castration ma ọ bụ luteinizing hormone-releasing hormone (LHRH).

Ojiji nke Bicalutamide

• Ọgwụgwọ Ọrịa Cancer Prostate: A na-eji ya agwọ ọrịa kansa prostate dị elu, nke na-ejikọta ya na usoro ọgwụgwọ hormone ndị ọzọ.
• Usoro ọgwụgwọ mgbakwunye: Ejiri ya na analogs LHRH dị ka leuprolide iji nweta mgbochi androgen zuru oke.
• Akwụsịghị Label na-eji: Edere oge ụfọdụ maka ọnọdụ dị ka hirsutism (oke ntutu isi) ma ọ bụ ọgwụgwọ homonụ na-akwado nwoke na nwanyị na ụmụ nwanyị transgender.

Usoro onunu ogwu nke Bicalutamide

Maka ọrịa cancer prostate:

• Ndị Okenye (Ọnọdụ nkịtị): 50 mg ọnụ otu ugboro kwa ụbọchị, a na-aṅụ ya n'otu oge kwa ụbọchị.

Maka Ejighị Label:

• Usoro onunu ogwu nwere ike ịdị iche dabere na ọnọdụ yana mkpa onye ọrịa. Soro ndụmọdụ ndị nlekọta ahụike mgbe niile.

Ntuziaka nchịkwa:

• Enwere ike iji ya ma ọ bụ na-enweghị nri.
• Jiri mmiri loda mbadamba nkume ahụ dum.

mkpa: Akwụsịla ọgwụgwọ ahụ n'amaghị onye na-ahụ maka ahụike gị, n'ihi na ọ nwere ike ime ka ọrịa kansa ka njọ.

Mmetụta nke Bicalutamide

A na-anabatakarị Bicalutamide nke ọma, mana ọ nwere ike ịkpata mmetụta dị n'akụkụ ụfọdụ ndị ọrịa.

Mmetụta emetụtakarị:

• Ogbugba ọkụ
• ike ọgwụgwụ
• Adị nro ma ọ bụ ọzịza (gynecomastia)
• ọgbụgbọ
• afọ ọsịsa

Mmetụta dị egwu:

• Nsi imeju: Nwere ike ibute mmụba nke enzymes imeju ma ọ bụ mmebi imeju. Ihe mgbaàmà ya gụnyere jaundice (ịcha akpụkpọ ahụ ma ọ bụ anya na-acha odo odo) na mmamịrị gbara ọchịchịrị.
• Mmeghachi omume nfụkasị ahụ: Ihe ọkụ ọkụ, itching, ma ọ bụ ọzịza.
• Nsogbu iku ume: Mkpụmkpụ iku ume ma ọ bụ ọrịa akpa ume n'etiti (ọ dị ụkọ).

Atụmatụ:

• A na-atụ aro nyocha ọrụ imeju oge niile n'oge ọgwụgwọ.
• Jiri nlezianya mee ihe na ndị ọrịa nwere akụkọ ihe mere eme nke imeju ma ọ bụ ọrịa ngụgụ.

Mmekọrịta na ọgwụ ndị ọzọ

Bicalutamide nwere ike iji ọgwụ ụfọdụ na-emekọrịta ihe, nwere ike imetụta arụmọrụ ha ma ọ bụ na-abawanye mmetụta.

• Ọgwụ mgbochi ọbara (dịka ọmụmaatụ, Warfarin): Nwere ike ịkwalite mmetụta anticoagulant, na-abawanye ohere ọbara ọgbụgba.
• Ihe ndị mejupụtara enzyme CYP450: Bicalutamide nwere ike igbochi ụfọdụ enzymes imeju, na-emetụta metabolism nke ọgwụ dị ka midazolam ma ọ bụ statins.
• Analọg LHRH: A na-ejikarị ọnụ maka mgbochi androgen zuru oke mana enwere ike ịbawanye mmetụta dị ka ọkụ ọkụ ma ọ bụ ike ọgwụgwụ.
• Ọgwụ ndị a na-ejide onwe ha: Ọgwụ dị ka phenytoin ma ọ bụ carbamazepine nwere ike ibelata ọkwa Bicalutamide, na-achọ mmezi dose.
• Mmeju ahịhịa: Ihe mgbakwunye dịka St. John’s Wort nwere ike igbochi arụmọrụ ya.

Uru nke Bicalutamide

• Mgbochi Hormone dị irè: Na-enye mbelata androgen zuru oke mgbe ejikọtara ya na analogs LHRH.
• Nhọrọ na-adịghị emerụ ahụ: Nlekọta ọnụ na-enye ihe ọzọ na-akpa ike karịa nkedo ịwa ahụ.
• Ogo ndụ emelitere: Na-enyere aka ịchịkwa mgbaàmà nke ọrịa kansa prostate dị elu, dị ka mgbu ọkpụkpụ na nsogbu urinary.
• Ngwa sara mbara: Ọ bara uru ma ọ bụ dị ka ọgwụgwọ otu ugboro dabere na ọnọdụ onye ọrịa.
• Ntinye aka pere mpe na ndụ kwa ụbọchị: Dosing otu ugboro kwa ụbọchị na mmetụta ndị nwere ike ime ka ọ dị mma maka iji ogologo oge.

Ajụjụ gbasara Bicalutamide

• Kedu ihe a na-eji Bicalutamide eme? A na-ejikarị Bicalutamide agwọ ọrịa kansa prostate dị elu site na igbochi mmetụta nke testosterone.
• Kedu ka Bicalutamide si arụ ọrụ? Ọ na-ejikọta na androgen receptors, na-egbochi homonụ nwoke na-akpali uto cancer.
• Enwere ike iji Bicalutamide naanị ya? A na-ejikọta ya na analogs LHRH, mana n'ọnọdụ ụfọdụ, enwere ike iji ya naanị maka mkpa onye ọrịa.
• Kedu ihe na-akpatakarị mmetụta ọjọọ nke Bicalutamide? Mmetụta ndị a na-ahụkarị gụnyere ọkụ ọkụ, ike ọgwụgwụ, nro ara, na ọgbụgbọ.
• Bicalutamide ọ dị mma maka ojiji ogologo oge? Ee, mana nleba anya mgbe niile, ọkachasị ọrụ imeju, dị mkpa.
• Bicalutamide ọ nwere ike imetụta ọmụmụ nwa? Ee, ọ nwere ike ibelata ọmụmụ site na ibelata ọkwa testosterone.
• Kedu ka m ga-esi were Bicalutamide? Were 50 mg ọnụ otu ugboro kwa ụbọchị, na nri ma ọ bụ na-enweghị nri, n'otu oge kwa ụbọchị.
• Kedu ihe m ga-eme ma ọ bụrụ na m na-atụ uche dose? Were ọgwụ ahụ a tụfuru ozugbo ị chetara ma ọ bụrụ na ọ fọrọ obere ka ọ bụrụ ọgwụ ọzọ a tụrụ aro. Ejila ya ugboro abụọ.
• Ụmụ nwanyị hà nwere ike iji Bicalutamide? Ọ bụghị FDA-akwadoro maka ojiji na ụmụ nwanyị mana enwere ike ịnye ya aha maka ọnọdụ ụfọdụ.
• Bicalutamide ọ na-emekọ ihe na ọgwụ ndị ọzọ? Ee, ọ nwere ike na-emekọrịta ihe na ọgwụ mgbochi ọbara, ọgwụ mgbochi, na ụfọdụ mgbakwunye. Gwa dọkịta gị gbasara ọgwụ niile ị na-aṅụ.

Aha ika nke Bicalutamide

• Kasodex?

mmechi

Bicalutamide bụ ọgwụ dị mkpa n'ịgwọ ọrịa kansa prostate dị elu, na-enye mbelata androgen dị irè ma na-eme ka ndụ dịkwuo mma. Ngwakọta ya na usoro ọgwụgwọ ndị ọzọ na-emekarị ka nsonaazụ ọgwụgwọ dịkwuo mma. Nleba anya mgbe niile na nrube isi na usoro iwu kwadoro na-ahụ maka nchekwa na ịdị irè.