Ukwelashwa Kwamaseli Emoto

Ukwelashwa Kwamaseli Emoto

Isingeniso

Amaseli e-T ayisici sesimiso somzimba sokuzivikela esisetshenziswa ngumzimba ukulwa nomdlavuza nezinye izifo. Amaseli e-T ashintshwe ngofuzo aziwa ngokuthi amaseli e-chimeric antigen receptor T (CAR T). Ngokusebenzisa ikhono lamaseli e-T ashintshiwe ukuthola nokuqeda amaseli omdlavuza, ukwelashwa kwamaseli e-CAR T kuthuthukisa izithiyo zemvelo zomzimba ngokumelene nalesi sifo.

Inqubo

Njengomnikelo wegazi, igazi liqoqwa ezigulini ukuze lihlukanise ama-T cell. Lawa maseli e-T abe eseshintshwa elabhorethri ngaphansi kokuqondisa kochwepheshe ukuze aveze Isamukeli Se-Chimeric Antigen. Ngaphambi kokuphathwa kwe-Car T cell, iziguli zidinga ukwelashwa ngamakhemikhali ukuze zilungiselele imizimba yazo yokwelashwa kwe-Car T cell. Uma esegxiliwe, amaseli e-Car T kulindeleke ukuthi abone futhi anciphise amangqamuzana omdlavuza amelana ngokuvula amasosha omzimba.

Izinkomba

Kusukela ngo-2017, i-FDA igunyaze izindlela zokwelapha ze-Car T cell eziyisithupha zokwelapha umdlavuza wegazi njenge-Lymphomas, izinhlobo ezithile ze-Leukemia futhi muva nje, i-myeloma eminingi. Iziguli ezifanelekela ukwelashwa kwe-Car T cell kufanele zihlangabezane nemibandela ye-FDA futhi zibe nempilo enhle iyonke ukuze zikwazi ukubhekana nesikhathi sokulinda kanye nemiphumela engemihle engaba khona.

Izinzuzo

• Isikhathi sokwelashwa esifushane
• Iziguli ngokuvamile zingalulama kahle ngokunakekelwa okufanele nokubhekwa emavikini angu-2-3
• Isikhathi sokungenelela esisheshayo kanye nokufakwa okukodwa kwamaseli e-Car T