Leukemia

ʻO ka maʻi leukemia kahi ʻano maʻi koko hoʻoweliweli e pono ai ka ʻike mua a me ka mālama ʻana. Aia ma lalo kahi ʻikepili pōkole no ka hoʻomaopopo maikaʻi ʻana i ka maʻi.

Ua lawe ʻia mai kekahi kaikamahine he ʻumikūmāiwa makahiki i ko mākou hale maʻi ma ka Halemai ʻo Apollo, Navi Mumbai, i ka hoʻomaka ʻana o Dekemaba 2020 e kona mau mākua me nā hoʻopiʻi e pili ana i ka ʻeha nui o ke kaikamahine a me ke kuni kiʻekiʻe mau no nā pule ʻelua i hala. Ua loaʻa iā ia nā manawa he nui o ka luaʻi ʻana no nā lā 3-4 i hala. Eia kekahi, ua lōʻihi ka menstruation o ke kaikamahine i nā lā ʻewalu i hala. I ka nānā ʻana, ua ʻike ʻia ua keʻokeʻo ʻo ia a ua luhi. Loaʻa iā ia nā pehu i ʻike ʻia ma ka ʻāʻī a me kekahi mau kiko petechial ʻulaʻula ma kona mau lālā haʻahaʻa. Ua hōʻike kāna mau hoʻāʻo koko maʻamau i ka haʻahaʻa o ka hemoglobin (anemia koʻikoʻi), ka helu platelet haʻahaʻa (thrombocytopenia) a me ka helu keʻokeʻo kiʻekiʻe loa (leukocytosis). ʻO ka nānā wikiwiki ʻana i ka smear peripheral ma ka microscopy i loko o ka hale hana i hāpai i ka kānalua o ka leukemia ma lalo (ka maʻi ʻaʻai koko). ʻO nā leukemia he mau maʻi ʻaʻai koko ma muli o nā mutations i loko o nā genes a alakaʻi i ka ulu nui a me ka maʻamau ʻole o nā keʻokeʻo koko keʻokeʻo; ke pale nei kēia i ka ulu a me ka ulu ʻana o nā keʻokeʻo koko maʻamau i loko o ka iwi iwi. ʻAʻole ʻae kēia mau cell leukemic i nā cell koko ʻē aʻe (nā cell koko ʻulaʻula a me nā platelets) e ulu a hana, e alakaʻi ana i ka anemia a me ka thrombocytopenia i kēlā mau maʻi. Eia kekahi, ʻo ka wikiwiki maʻamau o ko lākou ulu ʻana ke kumu o ka hoʻonui ʻana o nā lua iwi a no laila e hōʻeha ai i ka ʻoluʻolu ʻole o ka iwi a me ka ʻeha e hōʻike nei kēia mau maʻi. ʻOiai ʻo nā WBC nā cell pale maʻi o ke kino, hoʻopilikia ko lākou mau ʻano ʻino i ka ʻōnaehana pale o ka mea maʻi, e alakaʻi ana i ka hiki ke pale aku i nā maʻi. No laila, pinepine, ʻo ke kuni kiʻekiʻe i kēlā mau maʻi ma muli o nā kūlana a lākou e ulu ai ma muli o ko lākou ʻōnaehana pale i hoʻopilikia ʻia.

Ua loiloi hou mākou i kēia mea maʻi me kahi hoʻokolokolo biopsy iwi iwi me kekahi mau hoʻokolohua molekala a ua hōʻoia i ka maʻi o ka Lymphoblastic Leukaemia acute (ALL). Ua hoʻokomo ʻia ka mea maʻi i kahi keʻena hoʻokaʻawale ma ka Halemai Apollo, a ua hoʻomaka ʻia ka lāʻau. Ua hana ʻo ia i ka chemotherapy induction 8-pule, a ukali ʻia e ʻelua mahina o ka chemotherapy consolidation. Ua hōʻoia kāna hana genetic i kahi ALL pilikia kiʻekiʻe, a no laila ua hoʻomau ʻo ia me kahi hoʻoili cell stem donor hoahānau i kūlike ma nā haukapila Apollo, Navi Mumbai. He 1 makahiki ʻo ia ma hope o ke kāpili ʻana a ua hoʻomaha piha ʻia, ke hana maikaʻi nei a ma ka nānā mau ʻana. Ua komo ʻo ia i kāna kulanui a ke alualu nei i nā haʻawina hou aʻe e hoʻopau i kāna hoʻonaʻauao.

ʻOiai he mea kakaikahi i waena o nā maʻi kanesa āpau, hiki ke hoʻokaʻawale ʻia nā Leukemia i nā leukemia ʻoi a me nā leukemia mau.

ʻO nā maʻi leukemia mau loa e komo pū me

· Ka maʻi leukemia Myeloid mau loa

· Leukemia Lymphocytic mau loa

ʻO nā maʻi leukemia koʻikoʻi e komo pū me

· Ka maʻi leukemia myeloid koʻikoʻi,

· Ka maʻi leukemia Promyelocytic koʻikoʻi

· Ka maʻi leukemia lymphoblastic koʻikoʻi (kelepona T, kelepona B)

· Kekahi mau maʻi leukemia i hui pū ʻia

He mau hōʻailona e kānalua ai i kahi maʻi hematological: ʻOi aku ka nui o kēia mau hōʻailona i ka wā e hōʻike ʻia ai i ka hui pū ʻana no ka mea ʻo nā kumu maʻamau e komo pū me ka viral fever, ka maʻi tuberculosis, nā maʻi autoimmune, a pēlā aku.

– Piʻi ke kuni mau me ka pohō kaumaha

– Ke piʻi wikiwiki nei ka helu o nā hunaola koko keʻokeʻo

– Ka pehu hou ʻana ma ka ʻāʻī a i ʻole ka ʻūhā

– ʻO ka splenomegaly nui e hoʻoulu ai i ka makemake ʻole a me ka pohō kaumaha

– ʻO ka maʻalahi o ka palapū ma muli o nā platelets haʻahaʻa a i ʻole nā ​​​​protein coagulation i hoʻopilikia ʻia.

– He moʻolelo ʻohana ikaika o ka maʻi leukemia

Pono nā maʻi leukemia i kahi hōʻoia kūpono no nā hopena maikaʻi loa. ʻOiai ʻo ka lōʻihi o ka mālama ʻana hiki ke hoʻoluhi kālā a me ka naʻau no nā ʻohana, loaʻa i kekahi mau ʻohana e like me ia ke kākoʻo kālā mai nā NGO a me kekahi mau hui ʻē aʻe. Eia kekahi, pono nā mea maʻi a me ko lākou mau ʻohana i ke kākoʻo kaiāulu a me ka noʻonoʻo e hiki ai ke hoʻomanawanui i kēia mau manawa paʻakikī. No laila, pono kahi ʻāpana Haematology/Oncology piha i kahi hui loea me nā Hematologists a i ʻole Oncologists, kahi hui maʻi maʻi, nā kahu maʻi oncology, kahi waihona koko hana piha, kahi kākoʻo ʻāpana mālama koʻikoʻi maikaʻi, nā limahana kaiāulu i hoʻolaʻa ʻia, nā psychologists lapaʻau a me ka mea nui loa, kahi hui i hoʻonohonoho pono ʻia i ka mālama ʻana i ka maʻi kanesa.

Nā mea i hoʻokomo ʻia e Kauka Punit Jain, Kūkākūkā, Kauka Hoʻololi Hemato-Oncology & Bone Marrow, Apollo Cancer Centers, Navi Mumbai