ʻO nā Theranostics

He mea hoʻi kēia i kapa ʻia ka lāʻau lapaʻau radionuclide i kuhikuhi ʻia ʻoiai ke kuhikuhi ʻia nei i ka pahuhopu molekala kikoʻī o nā hunaola kanesa e hana nei. No laila, hiki ke kuhikuhi ʻia kahi mahele kiʻekiʻe o ka radiation i ka puʻupuʻu me ka ʻole o ka hoʻopilikia ʻana i nā hunaola olakino maʻamau.

Pehea ka ʻokoʻa o ka theranostics mai ka radiotherapy kuʻuna?

Hiki i ka radiation therapy ke lilo i mea kūpono loa i ka mālama ʻana i ke kanesa, a i ʻole ka hōʻoluʻolu ʻana i nā hōʻailona i nā poʻe maʻi me nā maʻi kanesa pae holomua hiki ʻole ke mālama ʻia. Ma kahi o ka hapalua o nā poʻe maʻi kanesa āpau e loaʻa i ka radiation therapy i kekahi manawa o kā lākou mālama ʻana, kahi e hoʻohana ai i nā x-ray i hāʻawi ʻia i waho a i loko paha, nā protons a i ʻole nā ​​​​​​mea ikehu kiʻekiʻe ʻē aʻe e kuhikuhi a luku i nā cell kanesa. ʻOiai ua hōʻemi nā ʻano hana ʻenehana i hoʻomaikaʻi ʻia i ka hōʻino ʻana o nā ʻiʻo olakino, hoʻoulu mau ka radiotherapy kuʻuna i nā hopena ʻaoʻao i hiki ke paʻakikī i kekahi mau poʻe maʻi ke ʻae. Eia kekahi, ʻaʻole hiki i ka radiotherapy kuʻuna ke kuhikuhi i kahi o ka maʻi, e kaupalena ana i kona pono no nā poʻe maʻi me ka maʻi kanesa metastatic. Eia nō naʻe, ʻo ka radiotherapy kuʻuna kekahi o nā mea hana lapaʻau ikaika loa o ka oncology.

ʻO kēia ʻano hana hou i ka mālama ʻana i ka maʻi puʻupuʻu - ka lāʻau radionuclide i kuhikuhi ʻia - ke hana hou nei i ka hoʻohana ʻana i nā lāʻau lapaʻau radiation i ka oncology pololei a me ka hāʻawi ʻana i kahi papa hou o nā lāʻau lapaʻau kanesa. ʻO ka pahuhopu o ka hoʻomohala ʻana i ka lāʻau radionuclide i kuhikuhi ʻia, ʻo ia ka hoʻohui ʻana i nā isotopes alpha-, beta- a i ʻole gamma-particle e hoʻopuka ana - a i ʻole radionuclides - me nā peptides, antibodies, a i ʻole nā ​​​​mole liʻiliʻi, e hoʻomohala i nā lāʻau lapaʻau me ke kikoʻī kiʻekiʻe no kekahi mau ʻano tumors. Hāʻawi ʻia i ka mea maʻi ma o ka intravenous, ua hoʻolālā ʻia nā lāʻau lapaʻau radionuclide i kuhikuhi ʻia e hele pololei i ka tumor e hāʻawi i ka radiation therapeutic me ka pololei kiʻekiʻe. Manaʻo ʻia kēia pololei e kālele i ka hāʻawi ʻana o ka radiation i ka ʻiʻo tumor me ka hoʻemi ʻana i ka ʻike ʻana o ka radiation i nā ʻiʻo maʻamau.

He aha ke ʻano o ke kanesa e hiki ke mālama ʻia me nā theranostics?

Hiki i nā Theranostics ke lilo i mea pono i ka mālama ʻana i nā puʻupuʻu metastatic, inoperable i ke kahua holomua o ka maʻi e like me nā maʻi kanesa prostate, nā puʻupuʻu neuroendocrine o nā ʻano kino like ʻole e like me ka ʻōpū, pancreas, nā ʻōpū liʻiliʻi a me nā ʻōpū nui a me ka māmā. ʻO ka mea hope loa akā ʻaʻole ka mea liʻiliʻi loa, ʻo ka ablation post-operative o ke koena thyroid a me ka mālama ʻana i ka maʻi kanesa thyroid metastatic aia pū kekahi i loko o ka gamut o theranostics.

Loaʻa i nā maʻi kanesa i luna aʻe nā hōʻike lawa i loaʻa i kēia manawa e loaʻa ana kahi pōmaikaʻi maopopo i ka hoʻohana ʻana i ka lāʻau radionuclide. Eia nō naʻe, hiki i nā maʻi kanesa ʻē aʻe ke loaʻa kahi pōmaikaʻi ke hōʻike lākou i kekahi mau ʻano o nā mea loaʻa i manaʻo ʻia e like me ka fibroblast activation protein (FAP) a me nā mea loaʻa chemokine (CXCR4), hiki ke hoʻopaʻa ʻia me nā theranostics.