Hoʻopilikia nā microorganism i nā ʻano he nui o ko kākou olakino, me ka hoʻonui ʻana i ka pilikia o kekahi mau maʻi kanesa. Hiki i nā microorganism ke pāʻani i kahi kuleana i ka hoʻomaka ʻana a me ka holomua o ke kanesa ma o ka hana ʻana i nā mea ʻawahia e hōʻino ana i ka DNA a me nā metabolites carcinogenic. ʻOi aku ka paʻakikī o kēia mau huahana i nā puʻupuʻu i nā lāʻau chemotherapy a kāohi i ka pane pale o ke kino i ke kanesa.

Hoʻoponopono ʻia nā hāpana lapaʻau e like me ka pus, ka ʻiʻo, CSF, nā wai kino, ka sputum, ka broncho-alveolar lavage, ka mimi, ka ʻōpala a pēlā aku e nā ʻano hana moʻomeheu maʻamau a kālailai ʻia ma ke ʻano microscopic. Hoʻokaʻawale ʻia nā bacteria a me ka hū mai nā hāpana lapaʻau ma o nā ʻano hana moʻomeheu a hoʻāʻo ʻia no ko lākou maʻalahi i nā antibiotics a me nā antifungal. Ke alakaʻi nei kēia mau ʻano hana diagnostic i ke kauka me ka ʻike kūpono o nā maʻi bacteria, fungal a me mycobacteria, e kōkua ana i ka hoʻomaka koke ʻana o ka lāʻau antibiotic, antifungal a i ʻole anti tubercular.

Hāʻawi ʻia ka hōʻoia serological no nā maʻi HIV, Hepatitis B a me Hepatitis C ma o ka nānā ʻana i nā hāpana serum ma kahi mea loiloi Immuno automated. Hana ʻia ka ʻike ʻana i ka antibody e kūʻē iā Cytomegalovirus, Herpes simplex virus ma o ke ʻano hana ELISA. ʻO kahi hoʻāʻo diagnostic serological kūikawā a kū hoʻokahi i hāʻawi ʻia ma kā mākou keʻena ʻo ia ka Aspergillus galactomannan antigen ELISA based assay.