Pilikino Lapaʻau

Hāʻawi ka 'Oihana i nā lawelawe kūlana kiʻekiʻe loa a me ka hōʻoiaʻiʻo maikaʻi e hoʻokō i ka pahuhopu multi-disciplinary o ka hoʻokō ʻana i ka hōʻoia pololei a me ka mālama palekana, pololei a me ka maikaʻi o ka mea maʻi e hoʻohana ana i ka radiation.

Ua hoʻonohonoho ʻia ka ʻoihana e hāʻawi i ka lawelawe kūikawā, i hana ʻia no ka pono o kēlā me kēia mea maʻi, ma o ke ʻano ʻepekema i hoʻokumu ʻia i nā hōʻike, nā protocols i hoʻokumu ʻia, ka hoʻonaʻauao a me ka noiʻi hou. Mālama ka ʻoihana i ka mālama ʻana i nā lula no ka hoʻohana ʻana i ka radiation ionizing ma nā ʻoihana like ʻole o ka haukapila.

ʻO ka hāʻawi ʻana i ka lāʻau lapaʻau e komo pū ana me: chemotherapy, hormone therapy, targeted therapy, biological therapy a me immunotherapy. Hoʻohana nui ʻia ia ma nā kūlana aʻe:

• Hoa hui pū me ka radiotherapy e hoʻonui i ka pono o ka radiation.
• Ka lāʻau lapaʻau Neoadjuvant: Hāʻawi ʻia ma mua o ka lāʻau lapaʻau hope loa hiki ke lilo i chemo-radiotherapy a i ʻole ke ʻoki kino. Hāʻawi ʻia kēia e hana i nā maʻi kanesa hiki ʻole ke hana ʻia
  hiki ke hana ʻia ma ka hōʻemi ʻana i ka nui i kekahi mau maʻi.
• Lapaʻau Adjuvant: Hana ʻia kēia ma hope o ke ʻoki ʻana e hōʻemi i ka pilikia o ka hoʻi hou ʻana.
• Ka Lapaʻau Palekana: No ka kaohi ʻana i nā maʻi kanesa holomua (ke kanesa i pālahalaha ma waho o kahi i hānau ʻia ai) a i ʻole ke kanesa kūloko i holomua ʻole i hiki ke ʻoki ʻia a i ʻole ka radiotherapy.

ʻO ke kū hoʻokahi o ka ʻoihana

ʻO ka hui mua ma Hema Hikina-ʻĀsia e kauoha lapaʻau i kahi hale hana proton scanning beam penikala kiʻekiʻe loa. Ua hoʻokō pono ka hui i nā ʻano hana proton therapy hou loa no nā wahi lapaʻau like ʻole me nā hihia paʻakikī loa.

ʻO ka ikaika o ka keʻena aia i ka lawelawe hui pū ʻana i hāʻawi ʻia e kahi hui o nā kānaka lapaʻau physicists i loea i nā wahi kikoʻī me ka pahuhopu hope loa o ka hāʻawi ʻana i ka mālama maikaʻi loa i ka mea maʻi.

ʻIkepili o ke Kauka Lapaʻau

He poʻe loea olakino nā physicists lapaʻau me ka hoʻonaʻauao a me ke aʻo kūikawā i nā manaʻo a me nā ʻano hana o ka hoʻopili ʻana i ka physics i ka lāʻau lapaʻau. Loaʻa i nā physicists lapaʻau āpau i ka hui ka ʻike nui i ka radiation therapy kiʻekiʻe a me nā ʻano hana kiʻi multi-modality, ka wehewehe ʻana, ka calibration a me ka hōʻoia maikaʻi o ka radiotherapy hou loa a me nā lako diagnostic me ka hoʻohana ʻana i nā mea ʻike radiation holomua, nā phantoms a me nā mea kani.

Ua loaʻa i nā lālā o ka hui ke aʻo kūikawā i ka proton beam therapy mai nā ʻoihana kaulana a puni ka honua.

• Dr. Dayananda Sharma Shamurailatpam, PhD, DipRP, MCMPI – (Poʻo, Keʻena o ke Kino Lapaʻau)
• Kauka MP Noufal, PhD, DipRP, MCMPI, MS – (Luna Hoʻonaʻauao Lapaʻau Kiʻekiʻe)
• ʻO Mr. Kartikeswar Patro, M.Sc., DipRP – (Loea Lapaʻau Kiʻekiʻe)
• Kauka K. Ganapathy, PhD – (Luna Hoʻonaʻauao Lapaʻau Kiʻekiʻe)
• Kauka A. Manikandan, PhD, DipRP – (Luna Hoʻonaʻauao Lapaʻau Kiʻekiʻe)
• Kauka T. Rajesh, PhD, MCMPI – (Luna Hoʻonaʻauao Lapaʻau Kiʻekiʻe)
• ʻO Mr. Mayur Sawant, M.Sc., DipRP – (Loea Lapaʻau)
• ʻO Mr. Suryakant Kaushik, M.Sc., DipRP – (Kauka Lapaʻau Lapaʻau ʻŌpio)

ʻO ka ʻenehana mālama proton ma APCC

ʻO ka ʻenehana mālama photon ma APCC

Nā lawelawe lapaʻau

Hāʻawi ke keʻena i nā lawelawe physics lapaʻau i hōʻoia ʻia i ka maikaʻi mai ke kauoha mua ʻana a hiki i nā lawelawe lapaʻau i kēlā me kēia lā a me ka nānā koʻikoʻi i nā ʻano loea like ʻole i loko o ka haukapila ma ke ʻano nui ma Radiation Oncology, Diagnostic radiology a me Nuclear Medicine.

Hoʻomaka: ʻO nā ʻano hana o kekahi lako hana hoʻopuka radiation hou, nā polokalamu pili a me nā mea kōkua e ana ʻia a loiloi pono ʻia ma hope o nā kūlana a me nā protocols aupuni a me ka honua. ʻO ka hoʻonohonoho pono ʻana e hōʻoia i ka ʻae ʻia mai ke kino hoʻoponopono aupuni a me ka hoʻohana palekana ʻana i nā lako no ka mālama ʻana i ka mea maʻi. Ma APCC, ua kauoha ʻia ʻo PROTEUS-PLUS a me ka ʻōnaehana RadiXact-X9 HT me RayStation pili (RaySearch Lab, Sweden) a me Precision (Accuray, USA) TPS e mālama i nā mea maʻi me ka hoʻohana ʻana i ka radiotherapy kiʻekiʻe e hoʻohana ana i ka photon a me ka proton. Hoʻomohala mau kā mākou hui i nā ʻano hana lapaʻau hou a hoʻokō ʻia ma hope o ka hōʻoia nui ʻana. Eia kekahi, ua kauoha pū ka hui i nā lako hana kiʻi hoʻopuka radiation like ʻole me Aquilion-LB Wide bore CT (Toshiba, Iapana) a me Biograph Vision Digital PET-CT (Siemens, Kelemānia).

Kalibrasi: Hoʻohālikelike a hoʻoponopono nā Kauka Lapaʻau Lapaʻau i ka lawe ʻana o ka nui o ka radiation e nā lako hana hoʻopuka radiation like ʻole ma hope o ke kūlana formalism honua a hōʻoia i hiki ke hahai ʻia a hiki i ke kūlana mua.

Ka hōʻoia maikaʻi: I mea e hōʻoia ai i ka hāʻawi palekana a pololei o ka nui o ka radiation i kuhikuhi ʻia i ka mea maʻi, hana ka ʻoihana i nā hōʻoia hōʻoia maikaʻi he nui o nā mīkini hāʻawi lāʻau lapaʻau (PROTEUS-PLUS a me RadiXact-X9 HT) a me nā ʻāpana pili i kēlā me kēia lā, pule, mahina a me makahiki. Hoʻomaopopo pū ka ʻoihana i ka hana pono o nā lako kiʻi i hoʻokomo ʻia i loko o ka mīkini proton/photon therapy (no ka hōʻoia mua ʻana o ke kūlana o ka mea maʻi) a me nā mīkini diagnostic ʻē aʻe.

Hoʻolālā lapaʻau: Pono nā maʻi i kākau inoa ʻia no kekahi ʻano o ka radiation therapy e hoʻomākaukau mua i kēlā me kēia ʻanuʻu ma hope o ka SOP o ka ʻoihana. Hoʻomaka ia me ka hoʻomākaukau ʻana o nā mea hana immobilization i hoʻopilikino ʻia a ukali ʻia e ka wehewehe ʻana o ka tumor a me nā ʻōpū koʻikoʻi me ka hoʻohana ʻana i nā kiʻi volumetric multi-modality (CT, MRI, PET). Hoʻohālikelike ʻia ka lāʻau i manaʻo ʻia ma ka TPS me ka hoʻohana ʻana i ke kumu hoʻohālike o ka mea maʻi a me ka mīkini. Hoʻopaʻa ʻia ka mahele lāʻau i loko o ka mea maʻi me ka hoʻohana ʻana i nā algorithms Monte-Carlo/convolution superposition akamai a pololei loa. Loiloi ʻia ka hoʻolālā lapaʻau i hana ʻia e kahi hui o ka Radiation oncologist a me Medical Physicist e hōʻoia i ka hoʻokō ʻana i ka pahuhopu lapaʻau i wehewehe mua ʻia.

Hoʻolālā ʻana i ka mālama ʻana o Proton: ʻO ka holomua ʻenehana o PROTEUS-PLUS e hiki ai iā mākou ke hoʻolālā a mālama i kā mākou mea maʻi me ke ʻano hana akamai loa o ka Intensity Modulated Proton Therapy (IMPT). Hoʻokō ʻia ka hoʻolālā lapaʻau no IMPT ma RayStation TPS. Pili ia i ka hoʻonui ʻana i ka iterative paʻakikī o ka hoʻopaʻa ʻana i ka ikehu proton he nui me nā tausani mau kiko proton, ko lākou mau kūlana, ka mamao a me nā kaumaha e hoʻokō ai i kahi mahele kūlike loa i ka puʻupuʻu a me ka mālama ʻana i nā ʻiʻo maʻamau e pili ana. Hoʻohana mākou i ka SFO, MFO, Hybrid a me Robust optimization ma muli o ka paʻakikī a me ke koi no ka hihia lapaʻau. Hoʻohana ʻia ka 4D robust optimization, Layer a me ka volumetric re-painting IMPT no ka puʻupuʻu dynamic. Hana mau ʻia ka Adaptive IMPT no nā wahi lapaʻau hōʻike.

Hoʻolālā ʻana i ka mālama ʻana i ka Photon/High Energy X-ray: Hana ʻia nā hoʻolālā lapaʻau radiation photon ma Precision TPS me ka hoʻohana ʻana i ka helical intensity modulated radiotherapy (IMRT) o nā wahi lapaʻau āpau. Hoʻomaʻamaʻa mau ʻia ʻo SBRT, frameless SRS, SRT a me ka adaptive radiotherapy no nā hihia i hōʻike ʻia. Ma waho aʻe o ka mālama ʻana i nā wahi lapaʻau paʻakikī he nui, ua hoʻomaka pū mākou i ka Total marrow irradiation (TMI)/Total marrow and lymphoid irradiation (TMLI) no ka manawa mua ma India.

Research

Ke komo ikaika nei ka ʻOihana Lapaʻau Lapaʻau ma APCC me nā hana noiʻi hou e pili ana i ka multi-modality imaging a me ka radiotherapy pololei kiʻekiʻe me ka hoʻohana ʻana i ka proton a me ke kukuna photon.

ʻO kā mākou mau makemake noiʻi i kēia manawa, ʻo ia ka hoʻomohala polokalamu kūloko, ka noiʻi ʻana i nā ʻano hana lapaʻau hou, ka naʻauao hana a me ke aʻo ʻana i ka mīkini, ke aʻo ʻana i nā laina cell in-vivo a me in-vitro, ka hoʻoponopono ʻana i nā nīnau i pane ʻole ʻia, ka ʻikepili nui mai ka faila log mīkini, a pēlā aku.

He nui nā papahana intramural e hana nei a me ka papahana hana pū me nā ʻoihana kaulana ma India a ma waho. Ke komo ikaika nei ka ʻoihana i nā hoʻokolohua lapaʻau a me nā papahana noiʻi e ʻimi ana i ka lawe ʻana i ka radiation ionizing a me non-ionizing i nā maʻi no nā kumu diagnostic a me therapeutic.

Loaʻa ka hopena o kā mākou noiʻi hoʻomau hou ma ka ʻĀpana Hoʻopuka Hou