Daaweynta Car T Cell

Daaweynta Car T Cell

Hordhac

Unugyada T waa qayb ka mid ah habdhiska difaaca jirka ee uu jidhku u isticmaalo la dagaallanka kansarka iyo cudurrada kale. Unugyada T ee hidde-sidaha lagu beddelay waxaa loo yaqaan unugyada T-ga ee soo-dhoweeyaha antigen-ka ee chimeric (CAR T). Iyada oo la adeegsanayo awoodda unugyada T ee la beddelay si loo helo loona tirtiro unugyada kansarka, daaweynta unugyada CAR T waxay hagaajisaa caqabadaha dabiiciga ah ee jirka ee ka dhanka ah cudurka.

Nidaamka

Sida ku-deeqidda dhiigga, dhiigga ayaa laga soo ururiyaa bukaannada si loo kala saaro unugyada T. Unugyadan T ayaa markaa lagu beddelaa shaybaarka iyadoo ay kormeerayaan khabiiro si ay u muujiyaan Chimeric Antigen Reseptor. Kahor maamulka unugyada Car T, bukaanku waxay u baahan yihiin in lagu sameeyo kiimoterabi si jidhkooda loogu diyaariyo daawaynta unugga Car T. Marka la geliyo, unugyada Car T ayaa la filayaa inay aqoonsadaan oo ay ka takhalusaan unugyada kansarka u adkaysta iyagoo hawlgeliya habka difaaca jidhka.

Tilmaamayaasha

Laga soo bilaabo 2017, FDA waxay ansixisay lix daawaynta unugyada Car T ee lagu daweynayo kansarka dhiigga sida Lymphomas, noocyo gaar ah oo Leukemia ah iyo dhawaanahan, myeloma badan. Bukaannada u qalma daawaynta unugga Car T waa inay buuxiyaan shuruudaha FDA oo ay guud ahaan caafimaad qabaan si ay u xakameeyaan muddada sugitaanka iyo waxyeellooyinka ka iman kara.

Faa'iidada

• Waqtiga daawaynta oo gaaban
• Bukaan-socodka ayaa caadi ahaan si fiican uga soo kabsan kara daryeel habboon iyo fiirsashada 2-3 toddobaad
• Waqtiga faragelinta degdega ah iyo faleebo hal unug ah oo Car T ah